Protection against free radicals (UVB irradiation) of a water-soluble enzymatic extract from rice bran. Study using human keratinocyte monolayer and reconstructed human epidermis

Santa-María, Consuelo; Revilla, Elisa; Miramontes, E.; Bautista, Juan; García-Martínez, A.M.; Romero, E.; Parrado, Juan

doi:10.1016/j.fct.2009.09.019

Cited by 24 publications

(9 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…O. sativa has been studied in anti aging treatment. Watersoluble enzymatic extract from O. sativa served as a protective screen against UV-B radiation on cultivated keratinocytes and in vitro reconstructed skin 60 . In the other study, the extract of O. sativa plants callus improve the human-skin barrier function 61 .…”

Section: Discussionmentioning

confidence: 99%

Antioxidant and Anti Aging Assays of <I>Oryza sativa</I> Extracts, Vanillin and Coumaric Acid

Widowati

Fauziah

Herdiman

et al. 2016

JNR

152

View full text Add to dashboard Cite

Ipomoea reniformis Chaos is claimed in Indian traditional medical practice to be useful in the treatment of epilepsy and neurological disorders. In the present study, pretreatment effect of methanolic extract of Ipomoea reniformis on epilepsy and psychosis was evaluated in rodents using standard procedures. Besides evaluating epileptic and behavioral parameters, neurotransmitters such as Gamma-Amino Butyric Acid (GABA) in epilepsy and in psychosis dopamine, noradrenaline and serotonin contents in the rodent brain were estimated. The extract pretreatment reduced maximal electro shock; Isoniazid (INH) and Pentylenetetrazole (PTZ) induced seizures and also significantly inhibited the attenuation of brain GABA levels by INH and PTZ in mice. These results suggested that the observed beneficial effect in epilepsy may be by enhancing the GABAergic system. The test drug also inhibited the apomorphine induced climbing and stereotyped behavior and showed significantly reduced levels of brain dopamine, noradrenaline and serotonin which may be due to blocking of central dopaminergic, noradrenergic and serotonergic pathways or by enhancing the GABAergic system. The results obtained in present study suggest that the title plant possesses antiepileptic and antipsychotic activities in rodents.

show abstract

Section: Discussionmentioning

confidence: 99%

Antioxidant and Anti Aging Assays of <I>Oryza sativa</I> Extracts, Vanillin and Coumaric Acid

Widowati

Fauziah

Herdiman

et al. 2016

JNR

152

View full text Add to dashboard Cite

show abstract

“…Assim como no presente estudo, Guimarães et al (21) Com o tempo, a pele passa por diferentes atividades diárias, assim como, ela está constantemente exposta ao estresse oxidativo induzido por espécies reativas de oxigênio (ROS) que irão causar danos futuros. As ROS são geradas tanto a partir de fontes endógenas, tais como subprodutos de oxidação aeróbica ou em resposta celular a inflamação, e à estímulos externos pró-oxidantes, tais como a radiação ultravioleta (2). De acordo com Tang e Bhushan (22) os cremes cosméticos podem prevenir ou aliviar esses danos.…”

Section: Discussionunclassified

“…With time the skin goes through various daily activities and it is constantly exposed to oxidative stress induced by reactive oxygen species (ROS) that will cause further damage. ROS are generated both from endogenous sources, such as byproducts of aerobic oxidation or cellular response to inflammation, and external pro-oxidant stimuli, such as ultraviolet radiation (2). According to Tang and Bhushan (22) skin cream can prevent or relieve these damages.…”

Section: Discussionmentioning

confidence: 99%

“…Este dano oxidativo na pele conduz à superprodução melanocítica de melanossomas e ao enfraquecimento da elastina e do colagénio enfraquecida (1), induz a expressão de citoquinas pró-inflamatórias (IL-1, IL-6 e TNF-b), e inibe a apoptose (2). A aplicação tópica de antioxidantes, tem provado ser eficaz em proteger a pele contra danos oxidativos (3), e fornece a maneira mais simples para reforçar o sistema de protecção endógena (1).…”

Section: Introductionunclassified

“…This oxidative damage in skin leads to melanocytic overproduction of melanosomes and to weakened elastin and collagen (1), induces expression of proinflammatory cytokines (IL-1, IL-6, and TNF-b) and inhibits apoptosis (2). Topical administration of antioxidants has proven to be effective in protecting the skin against oxidative damage (3), and it provides the most straightforward way to strengthen the endogenous protection system (1).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Antioxidant activity of Matricaria chamomilla L. extract and clinical efficacy of cosmetic formulations containing this extract and its isolated compounds

Nóbrega

Wagemaker

Campos

2013

BBR

View full text Add to dashboard Cite

249 Biomedical and Biopharmaceutical Research J o r n a l d e I n v e s t i g a ç ã o B i o m é d i c a e B i o f a r m a c ê u t i c a Antioxidant activity of Matricaria chamomilla L. extract and clinical efficacy of cosmetic formulations containing this extract and its isolated compounds AbstractTopical application of antioxidants has proven to be effective in protecting the skin against oxidative damage. Matricaria chamomilla L. extract has been used in cosmetic formulations. The aim of this study was to evaluate the antioxidant potential of chamomile extract as well as the clinical efficacy on skin hydration and mechanical properties of skin. The antioxidant activity of chamomile extract was evaluated by chemiluminescence (IC50 = 0.14 μg/mL). Stable formulations were supplemented with 0,5 cg/g α-bisabolol or cg/gwith 5,0 of Matricaria chamomile glycolic extract or with 0,01 cg/g of apigenin and applied on the volar forearm and face of 25 female subjects. Skin physiology was assessed before and after 2 hours (single application) and after a 2-and 4-week period of daily application. After a single application, all formulations increased the stratum corneum water content but only α-bisabolol and chamomile extract formulations reduced TEWL. The formulation with chamomile extract has shown the most pronounced result in the reduction of TEWL (27%). However, after 2-and 4-week application, only the extract formulation increased stratum corneum water content compared with the vehicle. Chamomile extract was effective in neutralizing free radicals and therefore presents an interesting potential in cosmetic formulations for this purpose. Keywords:Chamomile, Clinical Efficacy, Antioxidant Activity, Apigenin, Alpha-Bisabolol, ResumoA aplicação tópica de antioxidantes provou ser eficaz em proteger a pele contra danos oxidativos. O extracto de Matricaria chamomilla L. tem sido amplamente utilizado em formulações cosméticas. Assim, o objectivo deste estudo foi avaliar o potencial antioxidante do extracto de camomila, bem como a eficácia clínica na hidratação e nas propriedades mecânicas da pele. A actividade antioxidante do extracto de camomila foi avaliada por quimioluminescência (IC50 = 0,14 ug / mL). As formulações foram suplementadas com a α -bisabolol de fração mássica 0,5 cg/g ou com extracto glicólico de Matricaria chamomilla L. de fração mássica 5,0 cg/g ou com 0,01 cg/g de apigenina e aplicados na parte interna do antebraço e na cara de 25 mulheres. A fisiologia da pele foi avaliada antes e após 2 horas (aplicação única) e 2 e 4 semanas de aplicação diária. Depois de uma única aplicação, todas as formulações aumentaram a água do estrato córneo, mas apenas as formulações com α -bisabolol e extracto de camomila reduziram a PTEA . A formulação com o extracto de camomila mostrou o resultado mais marcante na redução PTEA (27%). No entanto, após 2 -e 4-semanas de aplicação, apenas a formulação contendo o extracto aumentou o a água no estrato córneo. O extracto de camomila, foi eficaz na neutralização de radicais livres e...

show abstract

Applications of Marine‐derived Peptides and Proteins in the Food Industry

Rasika¹,

Ranadheera²,

Vidanarachchi³

2013

Marine Proteins and Peptides

View full text Add to dashboard Cite

Protection against free radicals (UVB irradiation) of a water-soluble enzymatic extract from rice bran. Study using human keratinocyte monolayer and reconstructed human epidermis

Cited by 24 publications

References 36 publications

Antioxidant and Anti Aging Assays of <I>Oryza sativa</I> Extracts, Vanillin and Coumaric Acid

Antioxidant and Anti Aging Assays of <I>Oryza sativa</I> Extracts, Vanillin and Coumaric Acid

Antioxidant activity of Matricaria chamomilla L. extract and clinical efficacy of cosmetic formulations containing this extract and its isolated compounds

Applications of Marine‐derived Peptides and Proteins in the Food Industry

Contact Info

Product

Resources

About