Protean manifestations of intravenous drug use

Warner, Richard C.; Srinivasan, Jothsana

doi:10.1016/s1479-666x(04)80073-8

Cited by 13 publications

(7 citation statements)

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“…Previous studies also revealed that if general practitioners are not aware of the clinical findings of infected pseudoaneurysm, then this diagnosis can be missed. [ 2 7 ] The pathogenesis of these pseudoaneurysms in IV drug abusers consists of introduction of infected material by nonsterile techniques combined with inadvertent or intentional arterial trauma when venous access is impossible because of thrombosis. [ 16 ] If left untreated, they can lead to hemorrhage, sepsis, limb loss, and even death.…”

Section: Discussionmentioning

confidence: 99%

“…[ 1 ] Repeated punctures under septic conditions along with needle sharing habits among IV drug abusers result in various vascular complications. [ 2 ] In addition, patients who present with these complications frequently have viral infections, which are hazardous to healthcare workers. [ 3 ] Recently, there is an increase in incidence of these complications.…”

Section: Introductionmentioning

confidence: 99%

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Infected pseudoaneurysms in intravenous drug abusers: Ligation or reconstruction?

Saini

Luther

Mahajan

et al. 2014

Int J App Basic Med Res

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Background:Infected pseudoaneurysm in intravenous (IV) drug abusers is a serious clinical problem, with difficult and controversial management. With existing controversies regarding their optimal management, we present the results of simple ligation and local debridement for treatment of infected pseudoaneurysms.Patients and Methods:Records of 72 consecutive patients with pseudoaneurysms in IV drug abusers over the last 20 years were reviewed retrospectively.Results:Ligation and excision of pseudoaneurysm was done in all patients with delayed revascularization in only two patients. Four patients had amputations because they had gangrenous limbs on presentation. All other patients had healthy limbs at the time of discharge. There were three deaths, two due to sepsis with multiorgan dysfunction and one with hemorrhagic shock.Conclusion:Infected pseudoaneurysm should be managed by simple ligation of involved artery with delayed revascularization, if required.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Infected pseudoaneurysms in intravenous drug abusers: Ligation or reconstruction?

Saini

Luther

Mahajan

et al. 2014

Int J App Basic Med Res

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“…Furthermore, the drug users’ nutritional status (Kumar, 2007; Virmani et al, 2006) and lifestyle may also account for some of the medical problems observed (e.g. a heightened risk of infectious diseases due to needle sharing or promiscuity [Neaigus et al, 2007; Urbina & Jones, 2004; Warner & Srinivasan, 2004]).…”

Section: Neuropathology Associated With Chronic Amphetamine and Opiatmentioning

confidence: 99%

The Neuropsychology of Amphetamine and Opiate Dependence: Implications for Treatment

2007

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Chronic use of amphetamines and/or opiates has been associated with a wide range of cognitive deficits, involving domains of attention, inhibitory control, planning, decision-making, learning and memory. Although both amphetamine and opiate users show marked impairment in various aspects of cognitive function, the impairment profile is distinctly different according to the substance of abuse. In light of evidence showing that cognitive impairment in drug users has a negative impact on treatment engagement and efficacy, we review substance-specific deficits on executive and memory function, and discuss possibilities to address these during treatment intervention.

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“…Apart from transmission of pathogens the morbidity may be from the effects of the drug itself or from localised injury to blood vessels, nerves and tendons. 3,4 The other feared complication is formation of thrombus which may dislodge and obstruct a distant site paving way for ischaemic necrosis. [5][6][7] It may also give rise to organ failure and end stage renal disease.…”

Section: Discussionmentioning

confidence: 99%

Patient autonomy and doctor’s concern – a case of intravenous drug abuser

2017

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Intravenous substance abuse is often associated with physical and psychological harm, and often requires urgent medical attention. We report a case of a young male who presented with life-threatening complications of intravenous drug abuse, but refused to give details or agree to the proposed treatment, raising concerns for the team of doctors. A compos mentis patient has a right to decide what should be done to his body. Medical management or surgical interventions cannot be initiated without the patient's consent even if these are lifesaving procedures, or a procedure meant to benefit the patient. Medical practitioner can be liable for assault (criminal law), medical negligence (law of tort), damages (civil action) and even human rights issues may be raised if a patient's autonomy is not respected.

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Protean manifestations of intravenous drug use

Cited by 13 publications

References 1 publication

Infected pseudoaneurysms in intravenous drug abusers: Ligation or reconstruction?

Infected pseudoaneurysms in intravenous drug abusers: Ligation or reconstruction?

The Neuropsychology of Amphetamine and Opiate Dependence: Implications for Treatment

Patient autonomy and doctor’s concern – a case of intravenous drug abuser

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