Prospective Study of the Association between Fluoride Intake and Dental Fluorosis in Permanent Teeth

Martins, Carolina Castro; Paiva, Saul Martins; Lima-Arsati, Ynara Bosco de Oliveira; Ramos-Jorge, M.L.; Cury, Jaime Aparecido

doi:10.1159/000119520

Cited by 34 publications

(42 citation statements)

References 79 publications

(58 reference statements)

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“…26 Furthermore, a study estimating F intake either from diet, or dentifrice or a combination of both for children with and without DF, found a similar F intake for both groups of children. 27 An association between a higher frequency of tooth brushing and fluorosis was detected in this study, in agreement with other studies. 20,28 Although the frequency of tooth brushing was not precise, it was used as a proxy measurement for the amount of F toothpaste being ingested, 26 insofar as higher frequencies of tooth brushing are expected to increase the risk of F intake.…”

Section: Discussionsupporting

confidence: 93%

Factors associated with dental fluorosis in school children in southern Brazil: a cross-sectional study

et al. 2014

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Factors associated with dental fluorosis in school children in southern Brazil: a cross-sectional study Abstract: This cross-sectional study assessed risk factors for dental fluorosis (DF) among 8-to 12-year-old children in southern Brazil. Children attending 20 schools were randomly selected (n = 1,196). They were interviewed and their parents answered a questionnaire that was sent home. Prevalence of DF was 8.53% (modified Dean's criteria), and the prevalence of severe DF was 0.17%. The results of multiple logistic regression analyses indicated that DF was associated with a higher frequency of tooth brushing and with initial use of fluoride toothpaste at the emergence of the first tooth. DF does not constitute a public health problem in southern Brazil.

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Section: Discussionsupporting

confidence: 93%

Factors associated with dental fluorosis in school children in southern Brazil: a cross-sectional study

et al. 2014

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“…As a result of the development of various fl uoride products for individual and collective use, there has been an increase in the prevalence of dental fl uorosis 6 . Among these products, fl uoride toothpastes are used by children during tooth development.…”

Section: Introductionmentioning

confidence: 99%

Impact of dental fluorosis on the quality of life of children and adolescents

Lima

Neta

Moura

et al. 2014

Rev. odontol. UNESP

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ResumoIntrodução: A fluorose dentária é um distúrbio de alta prevalência decorrente da ingestão de íons fluoretos. Medidas preventivas para evitá-la ainda são controversas. Assim, conhecer o impacto que a fluorose pode causar na qualidade de vida de indivíduos é importante para o planejamento de políticas públicas de saúde. Objetivo: Avaliar o impacto da fluorose dentária sobre a qualidade de vida relacionada à saúde bucal (QVRSB) de crianças e adolescentes. Material e método: Foram avaliados 300 indivíduos na faixa etária de 8 a12 anos. O diagnóstico de fluorose foi realizado segundo o índice Thylstrup e Fejerskov e a qualidade de vida foi avaliada utilizando os questionários de Percepção da Criança 8-10 e 11-14. Foram incluídos pacientes com oito incisivos permanentes com coroas totalmente irrompidase excluídos os que apresentavam restaurações extensas, dentes fraturados, outros defeitos do esmalte dentário e os que usavam aparelho ortodôntico fixo. Os dados foram analisados no programa SPSS  (versão 18; Chicago, IL) e realizaram-se os teste Qui-quadrado, Fisher e Mann-Whitney. Foram considerados significantes valores de p<0,05. Resultado: A prevalência de fluorose foi 64,7%, sendo os graus leve e muito leve responsáveis por 80,3% dos casos. Crianças e adolescentes não tiveram impacto na QVRSB no escore geral e domínios sintomas orais, bem-estar emocional e social (p>0,05). Entretanto, apresentaram impacto no domínio limitação funcional (p = 0,039 e 0,013) para crianças e adolescentes respectivamente). Conclusão: Foi observada associação entre fluorose e qualidade de vida apenas no domínio funcional.Descritores: Fluorose dentária; qualidade de vida; percepção. AbstractIntroduction: Dental fluorosis is a disturbance of high prevalence caused by the ingestion of fluoride ions present mainly in toothpaste. Preventive measures to avoid it are still controversial. Thus, knowing the impact that fluorosis can cause on the population's quality of life it is important for planning public health policies. Objective: To evaluate the impact of dental fluorosis on the quality of life of children and adolescents. Material and method: We studied 300 subjects aged 8 to 12 years divided into 4 groups: children (8-10 years) and adolescents (10 to 12 years) with and without fluorosis. The diagnosis of fluorosis was performed according to the index Thylstrup and Fejerskov and quality of life was evaluated using Child Perceptions Questionnaire 8-10 and 11-14. The socio-demographic characteristics of the patients were also evaluated. For inclusion in the sample, selected patients should present eight permanent incisors with crowns fully erupted. Patients who had extensive restorations, fractured teeth, other dental enamel defects and who wore braces were excluded. Result: Fluorosis was present in 64.7% of the patients analyzed and in most cases (80.3%) was mild or very mild. In children, the average overall score of the questionnaire was 15.9 for the group without fluorosis and 18.3 for the group with fluorosis (p = 0.255). The te...

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“…(tABle 1). even if in literature few articles link the relationship between fluoride intake and dental fluorosis, 34 the evidence suggests that 0.05-0.07 mg fluoride/kg body weight/day should be considered the safety threshold beyond that the risk of fluorosis increased. 9,10 this value should be taken into account not only after weaning, but also in the preparation of infant formula when breast milk is not available.…”

Section: Discussionmentioning

confidence: 99%

Dental enamel, fluorosis and amoxicillin

et al. 2012

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Introduzione: l'amoxicillina è uno degli antibiotici più utilizzati in età pediatrica per il trattamento delle infezioni dell'alto tratto respiratorio ed in modo particolare per il trattamento dell'otite media, patologia frequente nella prima e seconda infanzia. da alcuni studi emerge che l'utilizzo di amoxicillina durante i primi anni di vita potrebbe essere associato ad una particolare forma di fluorosi dentale le cui lesioni si localizzano principalmente a livello dei primi molari permanenti e, seppure meno frequentemente a livello degli incisivi. gli effetti dell'amoxicillina sembrano essere indipendenti da altri fattori di rischio come assunzione di fluoro, prematurità alla nascita, ipossia, ipocalcemia, esposizione alla diossina, varicella, otite media, febbre alta e potrebbero avere un impatto significativo sulla salute orale per l'ampio uso di questo farmaco in questo periodo della vita. Obiettivo: lo scopo del nostro studio era quello di revisionare l'attuale letteratura riguardo l'associazione tra amoxicillina e fluorosi. Metodi e Risultati: e' stata effettuata una revisione della letteratura nei database PubMed e Cochrane usando le seguenti parole chiave: amoxicillin*, dental fluorosis*, dental enamel* e Mih*. dopo aver selezionato gli studi sono stati inclusi nella revisione solo tre articoli rilevanti, pubblicati tra il 1966 e il 2011. Conclusione: la presenza di numerosi problemi metodologici non ci permette di trarre conclusioni basate su evidenza scientifica. Sono necessari ulteriori studi per stabilire un'eventuale relazione tra amoxicillina e fluorosi. Sulla base dei dati attuali potrebbe essere comunque considerato un atteggiamento prudente quello di limitare la prescrizione di questo farmaco per infezioni ricorrenti delle alte vie respiratorie, specialmente per l'otite media, durante i primi due anni di vita, somministrando quando è possibile trattamenti antibiotici alternativi. AbstractIntroduction: Amoxicillin is one of the most used antibiotics among pediatric patients for the treatment of upper respiratory tract infections and specially for acute otitis media (AOM), a common diseases of infants and childhood. It has been speculated that the use of amoxicillin during early childhood could be associated with dental enamel fluorosis, also described in literature with the term Molar Incisor Hypomineralization (MIH), because they are generally situated in one or more 1 st permanent molars and less frequently in the incisors. The effect of Amoxicillin seems to be independent of other risk factors such as fluoride intake, prematurity, hypoxia, hypocalcaemia, exposure to dioxins, chikenpox, otitis media, high fever and could have a significant impact on oral health for the wide use of this drug in that period of life. Objective: The aim of this work was to review the current literature about the association between amoxicillin and fluorosis. Methods and Results: A literature survey was done by applying the Medline database (Entrez PubMed); the Cochrane Library database of the Cochrane Collaboration

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Prospective Study of the Association between Fluoride Intake and Dental Fluorosis in Permanent Teeth

Cited by 34 publications

References 79 publications

Factors associated with dental fluorosis in school children in southern Brazil: a cross-sectional study

Factors associated with dental fluorosis in school children in southern Brazil: a cross-sectional study

Impact of dental fluorosis on the quality of life of children and adolescents

Dental enamel, fluorosis and amoxicillin

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