Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication

Itô, Shinya; Blajchman, Aviva; Stephenson, Megan; Eliopoulos, Chrisoula; Koren, Gideon

doi:10.1016/s0002-9378(11)90771-6

Cited by 212 publications

(113 citation statements)

References 11 publications

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“…111,112 In a prospective study of 15 breastfeeding mothers taking aspirin therapy, no negative effects were noted (Tables S4, S5). 113 Recommendations 4.0.1. For lactating women using warfarin, acenocoumarol, or UFH who wish to breast-feed, we recommend continuing the use of warfarin, acenocoumarol, or UFH (Grade 1A) .…”

Section: Use Of Aspirin In Breast-feeding Womenmentioning

confidence: 99%

VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy

Bates

Greer

Middeldorp

et al. 2012

Chest

1,287

591

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Summary of RecommendationsNote on Shaded Text: Throughout this guideline, shading is used within the summary of recommendations sections to indicate recommendations that are newly added or have been changed since the publication of Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Recommendations that remain unchanged are not shaded. Abbreviations: APLA 5 antiphospholipid antibody; aPPT 5 activated partial thromboplastin time; HIT 5 heparin-induced thrombocytopenia; INR 5 international normalized ratio; LMWH 5 low-molecular-weight heparin; NNT 5 number needed to treat; PE 5 pulmonary embolism; RR 5 risk ratio; UFH 5 unfractionated heparin

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Section: Use Of Aspirin In Breast-feeding Womenmentioning

confidence: 99%

VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy

Bates

Greer

Middeldorp

et al. 2012

Chest

1,287

591

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“…Flimsy evidence suggests diazepam and chlordiazepoxide may be preferable to other benzodiazepines (Ito et al, 1993).…”

Section: Breastfeedingmentioning

confidence: 99%

British Association for Psychopharmacology consensus guidance on the use of psychotropic medication preconception, in pregnancy and postpartum 2017

et al. 2017

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Decisions about the use of psychotropic medication in pregnancy are an ongoing challenge for clinicians and women with mental health problems, due to the uncertainties around risks of the illness itself to mother and fetus/infant, effectiveness of medications in pregnancy and risks to the fetus/infant from in utero exposure or via breast milk. These consensus guidelines aim to provide pragmatic advice regarding these issues. They are divided into sections on risks of untreated illness in pregnancy; general principles of using drugs in the perinatal period; benefits and harms associated with individual drugs; and recommendations for the management of specific disorders.

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“…cas e psicoafetivas [1][2][3][4][5][6][7][8][9] . Porém, apesar de todas essas vantagens, alguns estudos revelam reduzidas taxas de amamentação materna em nosso meio e em outros países 4,7 .…”

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Does drug therapy in the postpartum period interfere with breastfeeding recommendations?

Lamounier¹,

Cabral²,

Oliveira³

et al. 2002

J Pediatr (Rio J)

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Artigo submetido em 03.05.01, aceito em 05.09.01. ResumoObjetivo: estudar a freqüência do uso de medicamentos no pós-parto imediato e verificar possíveis interferências nas recomendações quanto à amamentação.Métodos: foi realizado um estudo transversal em quatro maternidades de Belo Horizonte, no período de julho de 1998 a julho de 1999, incluindo 2.173 parturientes. A amostra foi calculada com base em dados da Secretaria Municipal de Saúde sobre o número de partos ocorridos nessas instituições, no ano de 1995, ou seja, em torno de 5% do total em um ano. A distribuição da amostra foi aleatória, utilizando o calendário de semanas epidemiológicas. Através de entrevistas junto às mães, usando um questionário próprio, e da coleta de dados obtidos de prontuários médicos da mãe e do recém-nascido, foi avaliada a freqüência do uso de medicamentos no pós-parto imediato. Os medicamentos foram agrupados em categorias quanto à compatibilidade com amamentação, à incompatibilidade, ao uso criterioso em monitorar e observar o recém-nascido para possíveis efeitos indesejáveis.Resultados: de um total de 2.173 mulheres, em 2.090 (96,2%) foram prescritos medicamentos no pós-parto imediato. Dos medicamentos utilizados, 2.054 (98,3%) foram de drogas sem contraindicação à amamentação natural; 338 (16,2%) foram de drogas sem informações seguras, e 3 (0,14%) de drogas contra-indicadas à amamentação.Conclusões: observou-se um amplo uso de medicamentos pelas mães nas maternidades de Belo Horizonte, no pós-parto imediato. A maioria das drogas é compatível com a amamentação, o que parece não influenciar negativamente a prática do aleitamento materno. AbstractObjective: to study the frequency of medication use in the immediate postpartum period and to evaluate possible effects on breastfeeding.Methods: a cross-sectional study was carried out with 2,173 women that gave birth in four hospitals in Belo Horizonte, a city in the southeast of Brazil, between July 1998 and July 1999. The sample was calculated by means of the data obtained from the City's Health Department according to the number of labors made in these four hospitals in 1995, which amounts to approximately 5% of the total number that usually occurs within a year. Women were randomized according to the calendar of epidemiological weeks. The interviews consisted of a questionnaire through which information about breastfeeding and sociodemographic data were obtained. In addition, the data were collected from mothers' and newborns' medical records. The drugs were classified according to their compatibility and incompatibility with breastfeeding, and were monitored as to the possible adverse effects on newborn infants.Results: 2,090 (96.2%) of 2,173 women received drug therapy in the immediate postpartum period. Among the drugs used, 2,054 (98.3%) were not contraindicated for breastfeeding; 338 (16.2%) did not contain safe information, and 3 (0.14%) were contraindicated.Conclusions: although drug therapy was widespread among the mothers followed up at these four hospitals, there seem...

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Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication

Cited by 212 publications

References 11 publications

VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy

VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy

British Association for Psychopharmacology consensus guidance on the use of psychotropic medication preconception, in pregnancy and postpartum 2017

Does drug therapy in the postpartum period interfere with breastfeeding recommendations?

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