Prophylactic use of indomethacin for prevention of postsurgical complications after removal of impacted third molars

Amin, Mohamed M.; Laskin, Daniel M.

doi:10.1016/0030-4220(83)90227-x

Cited by 109 publications

(60 citation statements)

References 10 publications

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“…We also assessed the percentage of facial swelling in both study and control groups according to the formula given by Mohammad Amin et al [24]. The percentage of facial swelling was numerically greater on the control side as compared to the study side at 2nd and 3rd post operative day.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Platelet Rich Plasma and Hydroxyapatite Crystals in Bone Regeneration After Surgical Removal of Mandibular Third Molars

Kaur¹,

Maria

2012

J. Maxillofac. Oral Surg.

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Purpose This study evaluates the efficacy of platelet rich plasma (PRP) & porous hydroxyapatite crystals in bone regeneration after surgical removal of mandibular third molar with the help of radiographs and its comparison with control side. Materials and Methods A total of 40 patients; both male and female aged between 18 and 35 years, who had impacted mandibular third molars were randomly selected for this study. Twenty patients were taken for control group and 20 patients for study group. The extraction socket of the study group was packed with PRP and hydroxyapatite granules and that of control group was sutured without PRP and hydroxyapatite. The bone density of both extraction sockets were evaluated radiographically using gray level histogram and compared periodically on immediate postoperative day, 1st and 3rd month postoperatively and postoperative sequelae of both the control group and study group in terms of oedema & pain or any other adverse reactions were also assessed. Results Data suggested evidence of early bone formation and maturation radiographically in study group as compared to control group. The percentage of facial swelling was numerically greater on the control side as compared to the study side, Pain was also assessed with VAS and it was found that the severity of pain was equal in both study and control groups and the results were not significant. Conclusion This study clearly indicated a definitive improvement in the wound healing, increase in bone density, which signifies and highlights the use of PRP and hydroxyapatite granules, certainly as a valid method in inducing and accelerating bone regeneration.

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Section: Discussionmentioning

confidence: 99%

Efficacy of Platelet Rich Plasma and Hydroxyapatite Crystals in Bone Regeneration After Surgical Removal of Mandibular Third Molars

Kaur¹,

Maria

2012

J. Maxillofac. Oral Surg.

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“…The obtained results, however, showed non-significant differences in the studied cytokine levels between the two types of treatment and the three days of sampling (p > 0.05), although high IL-6 production was observed in both treatment groups (Table 3). [21]. a p < 0.05 between day 0 and 3 in the ibuprofen group.…”

Section: Resultsmentioning

confidence: 99%

“…The measurement of facial swelling was done by the method described by Amin and Laskin [21]. The distance between the lower attachment of the ear lobe to the corner of the mouth, the distance between the lower attachment of the ear lobe to the mandibular symphysis and the vertical distance between the angle of the mandible to the outer canthus of the eye were measured by means of a silk suture.…”

Section: Measurement Of Swellingmentioning

confidence: 99%

Clinical trial evaluating the effectiveness of biocompound IMMUNEPOTENT CRP in the third-molar extraction

Franco‐Molina

Mendoza‐Gamboa

Coronado‐Cerda

et al. 2016

Biotechnology & Biotechnological Equipment

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A controlled, parallel, randomized and comparative trial was carried out to evaluate the antiinflammatory efficacy of IMMUNEPOTENT CRP versus ibuprofen in patients after third-molar surgery over seven days. The anti-inflammatory efficacy of IMMUNEPOTENT CRP was evaluated using the method of Amin and Laskin, and the analysis of cytokine production (IL-2, IL-4, IL-6, IL-10, TNF-a, INF-g) in saliva was done by flow cytometry. The swelling process after surgery was significant (p < 0.05) and the treatments with IMMUNEPOTENT CRP or ibuprofen controlled this process properly; no difference between the groups was found (p < 0.05). Both treatments were shown to modulate the cytokine production. These results demonstrate the anti-inflammatory activity of the natural compound IMMUNEPOTENT CRP and suggest it could be used in clinical dental practice.

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“…[1,2] Impacted third molar surgery, the most common type of oral surgery procedure, can also cause severe inflammation and pain postoperatively. [3,4] In order to secure a more comfortable operative procedure, instead of local anesthesia, the patient may be provided with conscious sedation by one of several methods, including 'inhalation conscious sedation', 'intramuscular conscious sedation' and 'intravenous conscious sedation'. The standard technique used in dentistry and oral surgery is intravenous conscious sedation with midazolam, a benzodiazepine with a short half-life of 2-3 hours.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of NSAID (Lornoxicam) After Impacted Third-Molar Surgery With/Without Conscious Sedation: A Double-Blind Randomized Clinical Study

Özgül¹,

Or²

2018

IJDSR

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Aim: Pain and swelling following surgery for impacted third molars can be controlled by various methods. This study compared the analgesic and anti-inflammatory efficacy and tolerability of lornoxicam, aspirin and a placebo with and without conscious sedation in impacted mandibular third-molar surgery. Materials and Methods: 60 patients undergoing third-molar surgery were divided into 2 groups of conscious sedation and routine local anesthesia (n=30). Both groups were divided into three subgroups (n=10) that received either Lornoxicam, aspirin, or a placebo postoperatively. Results: In both the conscious sedation and local anesthesia groups, swelling reduction was significantly greater with Lornoxicam compared to aspirin and placebo (p< .05). Pain values were significantly lower for Lornoxicam group compared to both aspirin and placebo groups at 6, 12 and 24 hours postoperatively (p< .05). Conclusion: Conscious sedation resulted less pain and swelling. Moreover, Lornoxicam was found to be an effective analgesic and anti-inflammatory agent for use in conjunction with oral surgery.

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Prophylactic use of indomethacin for prevention of postsurgical complications after removal of impacted third molars

Cited by 109 publications

References 10 publications

Efficacy of Platelet Rich Plasma and Hydroxyapatite Crystals in Bone Regeneration After Surgical Removal of Mandibular Third Molars

Efficacy of Platelet Rich Plasma and Hydroxyapatite Crystals in Bone Regeneration After Surgical Removal of Mandibular Third Molars

Clinical trial evaluating the effectiveness of biocompound IMMUNEPOTENT CRP in the third-molar extraction

Efficacy of NSAID (Lornoxicam) After Impacted Third-Molar Surgery With/Without Conscious Sedation: A Double-Blind Randomized Clinical Study

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