Prophylactic and persistent efficacy of doramectin against Cochliomyia hominivorax in cattle

Efficacy of macrocyclic lactones for the control of larvae of the Old World Screw‐worm Fly (Chrysomya bezziana)

“…Both drugs have been reported to provide protection for periods of 12 or more days [21][22][23] but when compared under similar conditions, doramectin has been found to be the more persistent and efficacious. 13,24,25 Ivermectin has also been shown to be effective against C bezziana but, until now, there have been no published data dealing with the larvicidal activity of doramectin, eprinomectin or moxidectin. Of the three pour-on preparations tested in the current study, doramectin was the most efficacious, preventing the induction of myiases due to C bezziana for 7 to 14 days after treatment.…”

“…Because cattle treated with an injectable preparation of ivermectin can be expected to remain myiasis-free for 16 to 20 days, 5 it is clear that none of the topical formulations examined in this study can be suggested as potential alternatives. On the other hand, extrapolating from the data for Co hominivorax, 13,24,25 injectable doramectin seems likely to compare favourably with the injectable formulation of ivermectin for the prevention of C bezziana infestations. Further assays are needed to confirm this.…”

“…[10][11][12] Doramectin also exhibits broad-spectrum activity and, when used as an injectable preparation, has been shown to be superior to ivermectin for the control of NWS, Cochliomyia hominivorax. [13][14][15] In the current study, we compare the duration of protection afforded by a SR bolus of ivermectin with that afforded by pour-on formulations of eprinomectin, doramectin and moxidectin. Pour-on formulations are quick and easy to use and, if effective, they would probably be the delivery system best suited for an emergency control situation.…”

Field efficacy of injectable doramectin against Chorioptes bovis in naturally infected cattle

“…The high efficacy of injectable doramectin against C bovis may be related to the prolonged persistence of the activity of the drug which was reported against both nematodes (Wicks and others 1993) and parasitic arthropods (Gonzales and others 1993, Moya‐Borja and others 1993b, Clymer 1994).…”

Metodologia de produção de moscas estéreis de Cochliomyia hominivorax (Coquerel, 1858) (Diptera: Calliphoridae) no Brasil

“…Para os estudos de flutuação sazonal dos adultos e monitoramento populacional, podem-se empregar animais sentinelas (para obtenção de massa de ovos e larvas) (BAUMHOVER et al, 1955), iscas com fígado deteriorado ou armadilhas com atrativos artificiais (Swormlures) (para captura de adultos) (GRAHAM, 1985;DRUMMOND et al, 1988;MOYA-BORJA et al, 1993;HALL;WALL, 1995). Broce et al (1977) desenvolveram uma armadilha mais eficiente do que a armadilha padrão para blowflies (standard blowfly trap -STT) e melhor adaptada para o uso do Swormlure-2, a chamada Wind Oriented Trap (WOT).…”