Properties of naproxen ion-selective electrodes

Abstract

Naproxen membrane electrodes based on different plasticizers and the quaternary ammonium salts (QASs) dimethyldidecylammonium bromide, methyltrioctylammonium chloride, or tetraoctylammonium chloride, were prepared. The following basic parameters were investigated for the optimal electrode: measurement range (10), slope of the linear range of the calibration curve (-58.3 mV decade ), lifetime (2.5 months), dependence of the electrode potential on pH (5.5 -9.0), reproducibility of potential (1.2 mV) and selectivity coefficients in relation to selected organic and inorganic anions. The electrode was utilized for determination of naproxen in tablets by the calibration curve method and the standard addition method. © Versita Warsaw and Springer-Verlag Berlin Heidelberg.

Use of Plasticizers for Electrochemical Sensors

“…Comparing the results, the best electrodes, containing methyltrioctylammonium chloride (MTOA-Cl) in the membrane, are appropriately plasticized with DBP, NPOE and TEHP (Lenik et al, 2008). For electrodes containing tetraoctylammonium chloride (TOA-Cl) in the membrane, similar potentiometric responses were obtained.…”

Preparation and study of a naproxen ion-selective electrode

“…On the basis of the literature, there are limited scientific works on the use of ion-selective electrodes for naproxen determination [15][16][17][18]. These electrodes have different constructions: the electrode [15] with liquid membrane type, based on the use of tetraheptylammonium naproxenate, the electrode with polymeric membrane type with methyltrioctylammonium naproxenate [16], the electrode with graphite membrane based on mercury(I) naproxenate [17], and electrodes based on other quaternary ammonium salt in chloride and bromide forms with inner solution of naproxenate in NaCl solution [18].…”

Properties of ibuprofen ion-selective electrodes based on the ion pair complex of tetraoctylammonium cation

“…The description of the electrode construction was presented in earlier papers [39][40][41]. The membrane phase of the electrode consists of two layers placed in a teflon holder.…”

“…These were liquid contact electrodes too [50]. Analytical usefulness of the electrodes was tested by performing determinations of 2-(4-isobutylophenyl) propiate acid (ibuprofen) using these ibuprofen electrodes in synthetic samples of Ibuprofen (Sigma), and in pharmaceutical preparations Ibuprofen (Polfa, Pabianice, Poland) and Nurofen Forte Express (Reckitt Benckiser Healthcare International Ltd., Great Britain).…”