“…Normally, throughout the process of wound healing, the levels of MMPs increase in an acute wound and decrease as wound healing occurs. MMP-2 (gelatinase A, 72-kDa gelatinase) can degrade several matrix components including collagen types I, IV, V, VII, XI, and laminin (36). MMP-3 has the ability to hydrolyse collagen types II, III, IV, IX and laminin, while MMP9 (gelatinase B, 72 kDa) is able to degrade collagen types III, IV, V, XIV and elastin (37,38).…”