Projected numbers of people with movement disorders in the years 2030 and 2050

Bach, Jan-Philipp; Ziegler, Uta; Deuschl, Günther; Dodel, Richard; Doblhammer-Reiter, Gabriele

doi:10.1002/mds.23878

Cited by 139 publications

(95 citation statements)

References 16 publications

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“…Compared to the other studies, our higher incidence rates may be explained by1 the inclusion of the institutionalized population, which is missing in most other studies. In our study, 20% of all patients with PD were living in nursing homes, allowing us to analyze PD up to the highest ages;2 the over‐representation of less educated and chronically ill persons in the AOK 22. To quantify this overrepresentation of sick persons, we calculated death rates as an indicator of morbidity and compared them with death rates of the German population.…”

Section: Discussionmentioning

confidence: 99%

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Parkinson's disease in Germany: prevalence and incidence based on health claims data

2016

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BackgroundIn Germany, epidemiological information on Parkinson's disease (PD) is rare and outdated. Considering aging populations, current prevalences and incidence rates about this age‐related disease would be important for adequate public health planning.MethodsWe used newly available health claims data sets from the largest German health insurer dating 2004‐2007 and 2007‐2010 with an analysis population in the base years of 491 038 persons aged 50 and older. Quarter‐specific information about ICD‐10 diagnoses and PD drug prescriptions from the inpatient and outpatient sectors was used to validate PD cases. Estimations were presented for two validation strategies relying on repeated PD diagnoses (SIa) and on one PD diagnosis followed by at least one PD drug prescription (SIb).ResultsThe standardized prevalence was 797 (SIb) to 961/100 000 persons (SIa), showing an age‐specific increase up to category 85‐89 and a decline thereafter. The standardized incidence rate was 192 to 229/100 000 person‐years with a similar age‐specific shape. Prevalences and incidences rates were higher for men compared to women in regard to age.ConclusionsHealth claims data are found to be suitable for PD assessment using the repeated diagnoses or PD drug prescriptions as necessary criteria.

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Section: Discussionmentioning

confidence: 99%

“…With aging populations, the number of individuals affected by this incurable disease will almost double in Europe, USA, and Canada combined by 2050 2. Generally, PD is rare before age 60 (0.13%‐1.6%), increases with age, and can reach a maximum of 9% among people aged 80‐84.…”

Section: Introductionmentioning

confidence: 99%

Parkinson's disease in Germany: prevalence and incidence based on health claims data

2016

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“…No Brasil, a prevalência para pessoas acima de 64 anos é estimada em 3,3% 5 . Com o aumento da expectativa de vida, em 2030, aproximadamente, nove milhões de pessoas serão portadoras da DP nos dez países mais populosos do mundo 2,4,6 .…”

Section: Impacto Na Qualidade De Vida De Portadores De Doença De Parkunclassified

“…É caracterizada por manifestações motoras como tremores, acinesia ou bradicinesia; rigidez e instabilidade postural 2,4,6,7 . Aparecem também disfunções autonômicas, sintomas sensoriais, distúrbios mentais que alteram a cognição e pode afetar o temperamento destes indivíduos [6][7][8] . Muito comumente pode ocorrer disfunção olfatória, cãibras, dores, parestesias, incontinência urinária e constipação intestinal 6,8 .…”

Section: Impacto Na Qualidade De Vida De Portadores De Doença De Parkunclassified

Impact on the quality of life of patients whit Parkinson’s Disease with risk of dysphagia

Freire

Rieder

Schuh

et al. 2015

RNC

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RESUMOObjetivo. Avaliar o impacto na qualidade de vida de portadores da Doença de Parkinson (DP) com risco para disfagia. Método. Participaram pacientes com DP do ambulatório de Distúrbios do Movimento de um hospital de Porto Alegre; com classificação da doença pela escala Hoehn & Yahr; que responderam questionário fonoaudiológico, questionário EAT-10 e questionário SWAL-QOL. Resultados. A amostra foi composta de 25 sujeitos: 16 (64%) do sexo masculino. A média de idade foi de 64,5 anos e do tempo de doença de 11 anos. 18 (72%) participantes possuem H&Y entre 2 e 3. Houve correlação do questionário SWAL-QOL com o questionário fonoaudiológico, no domínio fadiga com queixa de emagrecimento recente (p=0,01), com mudança na consistência alimentar (p=0,015), com a atual consistência ingerida pelo paciente (p=0,02) e com alteração na fase oral (p=0,04); o domínio duração da alimentação com presença de escape anterior de saliva (p=0,01) e com a consistência referida na queixa (p=0,045); o domínio comunicação com alteração na fase oral (p=0,04) e com alimentação atual (p=0,036) e o domínio frequência dos sintomas com alteração na mastigação (p=0,038). Conclusão. Verificou-se que os portadores de DP com risco para disfagia sofrem impacto na qualidade de vida, principalmente, no domínio da comunicação oral. ABSTRACTObjective. To evaluate the impact on the quality of life of patients whit parkinson's disease with risk of dysphagia. Method. This study included patients with DP with risk of dysphagia who attended at the movement disorders clinic from a hospital in Porto Alegre. With disease staging according to the Hoehn & Yahr scale for disease severity; answered a Speech Therapy questionnaire, EAT-10 questionnaire and SWAL-QOL questionnaire. Results. The sample consisted in 25 patients: 16 (64%) male. The average age was 64.5 and the average disease duration was 11 years. 18 (72%) participants had H&Y between 2 and 3. The correlation between the SWAL-QOL and the Speech Therapy questionnaire were correlated with tiredness area and recent weight loss (p=0.01), change in the food consistency (p=0.015), current consistency ingested (p=0.02) and oral phase alteration (p=0,04); nutrition length area and saliva releasing (p=0.01) and consistency about dysphagia complaint (p=0.045); communication area (p=0.04) and oral phase alteration (p=0.036) as well as current nutrition and the area frequency of the symptoms and chewing alterations (p=0.038). Conclusion. It has been found that patients with Parkinson's disease with risk of dysphagia sufferers impact on quality of life, especially in the field of oral communication.

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“…Tremor is the most common movement disorder, and its prevalence is expected to increase in the next decades [1]. It appears due to a number of etiologically different disorders [2], none of which is fully understood [3].…”

Section: Introductionmentioning

confidence: 99%

Closed-Loop Modulation of a Notch-Filter Stimulation Strategy for Tremor Management with a Neuroprosthesis

et al. 2014

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Abstract-Tremor is the most common movement disorder, and one of the major causes of functional disability. In spite of the existence of various treatments, tremor is not managed effectively in a large number of patients, which make it a major cause of loss of quality of life. Here we present a novel strategy for tremor suppression through neurostimulation that replicates an adaptive notch-filter at the frequency of the tremor. The controller, which adapts the neurostimulation to the ongoing amplitude, frequency and phase of the tremor, is implemented in a wearable neuroprosthesis for tremor management. Experimental results in one patient with severe essential tremor illustrate the interest of the approach.

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Projected numbers of people with movement disorders in the years 2030 and 2050

Abstract: There will be a strong increase in the number of people affected by most movement disorders between 2010 and 2050. This increase will mostly depend on the future aging of populations in terms of their age structure and future life expectancy.

Cited by 139 publications

References 16 publications

Parkinson's disease in Germany: prevalence and incidence based on health claims data

Parkinson's disease in Germany: prevalence and incidence based on health claims data

Impact on the quality of life of patients whit Parkinson’s Disease with risk of dysphagia

Closed-Loop Modulation of a Notch-Filter Stimulation Strategy for Tremor Management with a Neuroprosthesis

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