Progressive Scleroderma of the Skin With Cystic Sclerodermal Changes of the Lungs

Pulmonary Manifestations in the Diffuse Collagen Diseases

“…Macroscopically, sclerodermatous lungs were found to be firm, inelastic and reduced in size. Dostrovsky (1947) described "pulmo-sclerosis cystica" with scleroderma occurring later in the disease. Pagel, Woolf, and Asher (1949) did not think that the lung pathology was specific.…”

“…Pulmonary manifestations in diffuse collagen disorders are not uncommon and changes varying from pleural effusions, partial consolidation, widespread reticulation, miliary mottling to chronic fibrosis and sclero-cystic lung disease have been described in the rheumatic diseases (Cheadle, 1888;von Glahn and Pappenheimer, 1926;Masson, Riopelle, and Martin, 1937;Hadfield, 1938;Gouley, 1938;Harkavy, 1941Harkavy, , 1943Rakov and Taylor, 1942;Baggenstoss and Rosenberg, 1943;Gregory and Rich, 1946;Jensen, 1946;Klemperer, 1948;Ellman, 1947;Ellman and Ball, 1948; van Wijk, 1948;and Lees, 1952); in polyarteritis nodosa (Weir, 1939;Elkeles, 1944;Miller and Daley, 1946;and Bergstrand, 1946); in disseminated lupus erythematosus (Tumulty and Harvey, 1949); and in scleroderma (Finlay, 1891;Kraus, 1924;Matsui, 1924;Murphy, Krainin, and Gerson, 1941 ;Linenthal and Talkov, 1941 ;Weiss, Stead, Warren, and Bailey, 1943;Jackman, 1943;Bevans, 1945;Getzowa, 1945;Goetz, 1945;Dostrovsky, 1947;Baehr and Pollack, 1947;Lloyd and Tonkin, 1948;McMichael, 1948 ;Wigley, Edmunds, and Bradley, 1949;Church and Ellis, 1950;…”

Lung and Pleural Changes accompanying Distant and Systemic Pathology

“…Case report : An elderly woman was known to us to have been suffering from scleroderma for several years. She developed a fibrosis compacta of the entire left lung which was described for the first time by Dostrovski 24 (Fig. 9).…”

Council on Foods and Nutrition

“…This level should be obtained by careful selection and processing rather than by the addition of synthetic ascorbic acid. 4. During the processing season, daily laboratory rec¬ ords should include ascorbic acid determinations in order to demonstrate the maintenance of the recommended vitamin C level.…”