Progress towards sheep and goat pox vaccines

Kitching, Paul

doi:10.1016/0264-410x(83)90004-x

Cited by 51 publications

(53 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The commercial vaccine against SP is a freeze-dried live attenuated Romanian Fanar strain adapted to the Vero cell line. Live attenuated vaccines provide long-lasting immunity and, hence, are considered the best choice for use in vaccination (14). In this paper, we report for the first time the preparation of a combination recombinant vaccine containing recombinant epsilon toxoid (rEtox) with aluminum hydroxide as an adjuvant and freezedried live attenuated SPV followed by its use as a vaccine in sheep.…”

mentioning

confidence: 99%

Development of a Recombinant Epsilon Toxoid Vaccine against Enterotoxemia and Its Use as a Combination Vaccine with Live Attenuated Sheep Pox Virus against Enterotoxemia and Sheep Pox

Chandran

Naidu

Parthasarathy

et al. 2010

Clin Vaccine Immunol

View full text Add to dashboard Cite

Sheep pox and enterotoxemia are important diseases of sheep, and these diseases cause severe economic losses to sheep farmers. The present study was undertaken to evaluate the potential of formaldehyde-inactivated recombinant epsilon toxin as a vaccine candidate. The potency of the recombinant epsilon toxoid with aluminum hydroxide as an adjuvant in sheep was determined. Vaccinated sheep were protected against enterotoxemia, with potency values of >5 IU being protective. Further, the use of this construct in a combination vaccine against sheep pox resulted in the sheep being protected against both sheep pox and enterotoxemia.

show abstract

mentioning

confidence: 99%

Development of a Recombinant Epsilon Toxoid Vaccine against Enterotoxemia and Its Use as a Combination Vaccine with Live Attenuated Sheep Pox Virus against Enterotoxemia and Sheep Pox

Chandran

Naidu

Parthasarathy

et al. 2010

Clin Vaccine Immunol

View full text Add to dashboard Cite

show abstract

“…Experimentally infected Aedes aegypti were infectious for 6 days, and transovarial and transstadial transmission were demonstrated in some species of ticks. Some lying arthropods, such as Culicoides , might introduce LSDV to new areas when they are carried by the wind [4,5].…”

Section: Resultsmentioning

confidence: 99%

“…In order to control further spreading of disease and control the situation was decided along with overall veterinary-sanitary measures (for example quarantine in Was taken account that only live attenuated vaccines against LSD are currently commercially available. Because of antigenic homology and cross-protection between sheep pox, goat pox and LSD viruses, any of these viruses can be used as a vaccine strain to protect cattle against LSD [4]. In OIE Terrestrial Manual described that all strains of Capripoxvirus examined so far, whether of bovine, ovine or caprine origin, share a major neutralizing site, so that animals recovered from infection with one strain are resistant to infection with any other strain.…”

Section: Resultsmentioning

confidence: 99%

Lumpy Skin Disease in Armenia

Markosyan¹,

Sargsyan²,

Kharatyan³

et al. 2017

J Vet Sci Technol

View full text Add to dashboard Cite

Lumpy skin disease is a poxvirus disease of economic importance. The first clinical cases of LSD in Armenia were registered in December 2015 among cattle which further was confirmed in laboratory in local and international levels. The source of LSDV was not identified and the role of vectors is not clear but there are some insects presented in country and which are known as a vector of LSDV transmission. For the control and prevention of the further spread of LSDV the vaccination with sheep pox live vaccine was conducted. During 2016 and first 9 months of 2017 in total 487518 cattle were vaccinated. In 2016 about 50% of total cattle population, which were located in risk zones, were vaccinated and in parallel with other control measures it have helped to stop further spread of LSDV in country.

show abstract

“…Endemik ülkelerde, LSD salgınlarının tek etkili kontrol yolu aşılamadır. Koyun çiçek, keçi çiçek ve LSD viruslarının antijenik homolojileri ve çapraz koruma oluşturma nedenlerinden dolayı bu virus suşlarından herhangi birisi, sığırları LSD'ye karşı korumak için kullanılabilmektedir [13,14] . Sonuç olarak, bu çalışma ile Doğu ve Güneydoğu Anadolu bölgelerinde yer alan Hakkari, Malatya, Şırnak ve Batman illerinde sığırlarda LSD hastalığının klinik teşhisi yapılmış ve uygulanan PCR yöntemi ile virus varlığının tespiti yapılarak klinik teşhis doğrulanmıştır.…”

Section: Tartişma Ve Sonuçunclassified

The Detection of Lumpy Skin Disease Virus Infection by Clinical Findings and PCR Method in Turkey

Gürçay¹,

Sait²,

Parmaksiz³

et al. 2015

Kafkas Univ Vet Fak Derg

View full text Add to dashboard Cite

Lumpy Skin Disease (LSD), sığır, bufalo ve bazı yabani türlerin derileri üzerinde nodüller ve ödem ile karakterize viral bir enfeksiyonudur. Bu çalışmada, LSD virus enfeksiyonunun, Türkiye'deki varlığının, enfekte sığırlarda gözlenen klinik bulgulara göre tanısı ve PCR yöntemi ile doğrulanması amaçlanmıştır. Bu amaçla, Eylül 2013-Haziran 2014 tarihleri arasında Türkiye'de yerleşik 8 sığır çiftliğinde klinik olarak LSD enfeksiyonu belirtileri gösteren 113 sığır incelendi. Daha sonra, bu sığırlardan 12 deri nodülü örneği alındı ve viroloji laboratuvarına getirildi. Bu örnekler OIE tarafından tanımlanan yönteme göre PCR ile test edildi. Enfeksiyonun klinik bulgularının PCR sonuçları ile uyumlu olduğu ortaya konuldu. Anahtar sözcükler: Lumpy Skin Disease, PCR, Epidemiyoloji The Detection of Lumpy Skin Disease Virus Infection by Clinical Findings and PCR Method in Turkey AbstractLumpy Skin Disease (LSD) is a viral disease of cattle, buffalo and some wild species characterized by oedema and nodules on the skin. The aim of this study was to report the presence and the clinical signs of LSD in infected cattle in Turkey, and to confirm by PCR method. For this purpose, 113 cattle showing clinical signs of LSD were examined from 8 settled farms in Turkey between September 2013 to June 2014. Then, 12 skin nodule samples from these cattle were obtained, and brought to the virology laboratory. The samples were tested by PCR according to the method described by OIE. The clinical diagnosis was well correlated with PCR results.

show abstract

Progress towards sheep and goat pox vaccines

Cited by 51 publications

References 18 publications

Development of a Recombinant Epsilon Toxoid Vaccine against Enterotoxemia and Its Use as a Combination Vaccine with Live Attenuated Sheep Pox Virus against Enterotoxemia and Sheep Pox

Development of a Recombinant Epsilon Toxoid Vaccine against Enterotoxemia and Its Use as a Combination Vaccine with Live Attenuated Sheep Pox Virus against Enterotoxemia and Sheep Pox

Lumpy Skin Disease in Armenia

The Detection of Lumpy Skin Disease Virus Infection by Clinical Findings and PCR Method in Turkey

Contact Info

Product

Resources

About