Programmable black phosphorus image sensor for broadband optoelectronic edge computing

Lee, Seokhyeong; Peng, Ruoming; Wu, Changming; Li, Mo

doi:10.1038/s41467-022-29171-1

Cited by 106 publications

(101 citation statements)

References 62 publications

(90 reference statements)

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“…As innate immune lymphocytes, NKs contribute to the body’s innate immunity and adoptive immunotherapy and exert functional activity against metastatic or hematological malignancies. − In addition to utilizing NKs directly, NK-derived exosomes have been shown in recent studies to exhibit good antitumor efficacy . NK-derived exosomes can activate a variety of cell death pathways in cancer cells, including endoplasmic reticulum stress-induced apoptosis and caspase-dependent/-independent apoptosis. , Modest concentrations of NK-derived exosomes can bind to the recipient cells in a short time due to the presence of cytotoxic proteins (IFN-γ, FasL, etc. )…”

Section: Immune Cell-derived Exosomes In Cancer Therapymentioning

confidence: 99%

Immune-Cell-Derived Exosomes for Cancer Therapy

2022

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Exosomes are a type of extracellular vesicles secreted by cells in normal or pathological conditions for cell–cell communication. With immunomodulatory characteristics and potential therapeutic properties, immune-cell-derived exosomes play an important role in cancer therapy. They express various antigens on their surface, which can be employed for antigen presentation, immunological activation, and metabolic regulation, leading to the killing of cancerous cells. In addition, immune-cell-derived exosomes have received extensive attention as a drug delivery platform in effective antitumor therapy due to their excellent biocompatibility, low immunogenicity, and high loading capacity. In this review, the biological and therapeutic characteristics of immune-cell-derived exosomes are comprehensively outlined. The antitumor mechanism of exosomes secreted by immune cells, including macrophages, dendritic cells, T cells, B cells, and natural killer cells, are systematically summarized. Moreover, the applications of immune-cell-derived exosomes as nanocarriers to transport antitumor agents (chemotherapeutic drugs, genes, proteins, etc.) are discussed. More importantly, the existing challenges of immune-cell-derived exosomes are pointed out, and their antitumor potentials are also discussed.

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Section: Immune Cell-derived Exosomes In Cancer Therapymentioning

confidence: 99%

Immune-Cell-Derived Exosomes for Cancer Therapy

2022

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“…Here, the incident photon flux coming from the semiconductor optoelectronic device induces level splitting that forms electron-hole pairs. With an increase in the generated electrons, the produced J ph , R, and D values increase, and all the photoreactor efficiencies increase [ 4 , 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Development of a Highly Efficient Optoelectronic Device Based on CuFeO2/CuO/Cu Composite Nanomaterials

et al. 2022

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Herein, an optoelectronic device synthesized from a CuFeO2/CuO/Cu nanocomposite was obtained through the direct combustion of Cu foil coated with Fe2O3 nanomaterials. The chemical, morphological, and optical properties of the nanocomposite were examined via different techniques, such as XRD, XPS, TEM, SEM, and UV/Vis spectrophotometer. The optical reflectance demonstrated a great enhancement in the CuFeO2 optical properties compared to CuO nanomaterials. Such enhancements were clearly distinguished through the bandgap values, which varied between 1.35 and 1.38 eV, respectively. The XRD and XPS analyses confirmed the chemical structure of the prepared materials. The produced current density (Jph) was studied in dark and light conditions, thereby confirming the obtained optoelectronic properties. The Jph dependency to monochromatic wavelength was also investigated. The Jph value was equal to 0.033 mA·cm−2 at 390 nm, which decreased to 0.031 mA·cm−2 at 508 nm, and then increased to 0.0315 mA·cm−2 at 636 nm. The light intensity effects were similarly inspected. The Jph values rose when the light intensities were augmented from 25 to 100 mW·cm−2 to reach 0.031 and 0.05 mA·cm−2, respectively. The photoresponsivity (R) and detectivity (D) values were found at 0.33 mA·W−1 and 7.36 × 1010 Jones at 390 nm. The produced values confirm the high light sensitivity of the prepared optoelectronic device in a broad optical region covering UV, Vis, and near IR, with high efficiency. Further works are currently being designed to develop a prototype of such an optoelectronic device so that it can be applied in industry.

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“…To address this problem, much effort has been devoted to develop an in-sensor computing technology by emulating certain functions of the human retina, for example, metalsemiconductor-metal variable-sensitivity photo-memristors (VSPDs), recon gurable 2D semiconductor photodiodes, gate-tunable van der Waals heterostructures, etc. The above sensors constitute a build-in arti cial neural network that can sense and process images simultaneously [8][9][10][11][12][13][14][15][16][17] . However, challenges still exist.…”

Section: Introductionmentioning

confidence: 99%

2D materials-based photo-memristors with tunable non-volatile responsivities for neuromorphic vision processing

Fu²,

et al. 2022

Preprint

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Conventional artificial-intelligence (AI) machine vision technology, based on the von Neumann architecture, uses separate computing and storage units to process the huge amounts of vision data generated in sensory terminals. The frequent movement of redundant data between sensors, processors and memory, however, results in high-power consumption and latency. A more efficient approach is to shift some tasks of the memory and computational to sensory elements which can perceive and process optical signal simultaneously. Here, we proposed a non-volatile photo-memristor, in which reconfigurable responsivity can be modulated by charge and/or photon flux through it and further stored in the device. The non-volatile photo-memristors consist of simple two-terminal architecture, in which photoexcited carriers and oxygen-related ions are coupled, leading to a displaced and pinched hysteresis of current-voltage characteristics. The non-volatile photo-memristors sets first implemented computationally complete logic for the photoresponse-stateful logic operations, for which the same photo-memristor serves simultaneously as logic gates and memory unit that uses photoresponse instead of light, voltage and memresistance as the physical state variable. Further changing the polarity of photo-memristors demonstrate great potential for in-memory sensing and computing with feature extraction and image recognition for neuromorphic vision processing.

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Programmable black phosphorus image sensor for broadband optoelectronic edge computing

Cited by 106 publications

References 62 publications

Immune-Cell-Derived Exosomes for Cancer Therapy

Immune-Cell-Derived Exosomes for Cancer Therapy

Development of a Highly Efficient Optoelectronic Device Based on CuFeO2/CuO/Cu Composite Nanomaterials

2D materials-based photo-memristors with tunable non-volatile responsivities for neuromorphic vision processing

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