2002
DOI: 10.1590/s0102-311x2002000600036
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Abstract: Screening programs for hemoglobinopathies target different population groups such as neonates, students, pregnant women, military personnel, recruits, and blood donors. The feasibility and efficiency of these programs basically depend on the population's receptivity, which in turn is related to highly complex economic, psychological, and sociocultural factors. The purpose of this study was to evaluate the population of Bragança Paulista, São Paulo, based on results from the blood donors' group and to compare t… Show more

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Cited by 4 publications
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“…12 In Bragança Paulista (São Paulo, Brazil) a prevalence of 1.68% of hemoglobinopathies and 1.13% of the SCT was found among 1846 blood donors. 13 …”
Section: Discussionmentioning
confidence: 99%
“…12 In Bragança Paulista (São Paulo, Brazil) a prevalence of 1.68% of hemoglobinopathies and 1.13% of the SCT was found among 1846 blood donors. 13 …”
Section: Discussionmentioning
confidence: 99%
“…A maior proporção de crianças com níveis de hemoglobina abaixo de 11,5 g/dL que possuem níveis normais de ferritina também pode ser explicada pela presença de outras anemias comuns na infância como a anemia megaloblástica, onde ocorre a deficiência de ácido fólico e vitamina B12, que são essenciais para o amadurecimento celular, sendo um tipo de anemia carencial, ou as anemias hereditárias que estão entre as doenças mais comuns determinadas geneticamente e possuem frequência comum na população brasileira, com consequente dispersão de genes anormais, que resultam em doenças como hemoglobinopatias e talassemias. (21) Crianças com hemoglobinopatias ou talassemias foram excluídas do presente estudo por meio de questionário preenchido pelos pais. Contudo, é possível que algumas crianças apresentassem traço talassêmico ou falcêmico, o qual é assintomático e pode não ter sido diagnosticado.…”
Section: Discussionunclassified
“…In countries with a high prevalence of the sickle cell trait (SCT), which is often determined by neonatal screening programs, a significant proportion of blood donors may be SCT carriers [1]. In Brazil, for example, where SCT prevalence ranges from 1.1% to 9.8% in the overall population [2], the trait is found in up to 2.48% of blood donors [3][4][5][6][7]. Because individuals with SCT are usually asymptomatic, many of them are unaware of their condition at the time of donation [1].…”
Section: Introductionmentioning
confidence: 99%