“…37 Environment-Related Factors: A full description of therapeutic options and their efficacy is beyond our intended scope in this article. Medical decision making must consider at least two conditional prognoses (eg, the prognosis with one treatment and the prognosis with an alternative treatment), hence, the prognostic significance of a therapeutic intervention 10,80 "N" factor 46,[80][81][82] Weight loss 51,52 Hypercalcemia 54 Performance status 55 Additional factors Anatomic Sex 52 "T" factor 46,[83][84][85][86][87] Tumor size [88][89][90] Age 91,92 Nodal level 86,93 Pleural cytology 63,94,95 Intrapulmonary metastasis 96…”