Production of parathyroid hormone by metastatic parathyroid carcinoma

Zisman, Elias; Buckle, Richard M.; Deftos, Leonard J.; Aurbach, G. D.; Morton, Donald L.; Bartter, Frederic C.; Potts, John T.

doi:10.1016/0002-9343(68)90176-9

Cited by 27 publications

(2 citation statements)

References 9 publications

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“…Transplanted parathyroid tissue in animals is capable of maintaining the serum calcium at normal levels. Moreover, in man secondary metastases in the lung from a parathyroid carcinoma (which would be without any special nervous innervation) have been shown directly to secrete parathyroid hormone by the demonstration of a veno-arterial difference in the concentration of hormone across the tumnour (Zisman et al 1968).…”

Section: _^1mentioning

confidence: 99%

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The Regulation of Calcium Metabolism [Abridged]

Buckle

1970

Proceedings of the Royal Society of Medicine

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Section: _^1mentioning

confidence: 99%

“…In man the concentration of hormone (expressed as its bovine equivalent) has been found to vary between 43-57 ,ug/g wet weight of adenoma (Buckle 1969b) and as little as 13 ,ug/g wet weight of parathooid carcinoma (Zisman et al 1968).…”

Section: _^1mentioning

confidence: 99%

The Regulation of Calcium Metabolism [Abridged]

Buckle

1970

Proceedings of the Royal Society of Medicine

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Carcinoma of the Parathyroid

Gittler¹

1972

Arch Intern Med

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Parathyroid carcinoma: A clinical study of seven cases of functioning and two cases of nonfunctioning parathyroid cancer

Aldinger

Hickey

Ibañez

et al. 1982

Cancer

100

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Seven cases of functioning and two cases of nonfunctioning parathyroid carcinoma are presented together with a general discussion of this disease. Functioning parathyroid carcinoma may be associated with prolonged survival. The morbidity and mortality from this disease are generally related to the prolonged hypercalcemia that occurs. The hypercalcemia is best treated with excision of local recurrences; however, this surgery is most often palliative and seldom curative. The best operative results were obtained when the disease could be localized preoperatively. Neck and mediastinal exploration in the absence of physical or radiographic evidence of recurrence failed to affect serum calcium levels. Two patients with nonfunctioning parathyroid cancer did poorly compared with those with functioning parathyroid carcinoma. The few cases reported in the literature are also suggestive of a more aggressive disease. The failure of this tumor to produce parathyroid hormone may allow it to escape clinical attention until it has achieved an advanced state.

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Production of parathyroid hormone by metastatic parathyroid carcinoma

Cited by 27 publications

References 9 publications

The Regulation of Calcium Metabolism [Abridged]

The Regulation of Calcium Metabolism [Abridged]

Carcinoma of the Parathyroid

Parathyroid carcinoma: A clinical study of seven cases of functioning and two cases of nonfunctioning parathyroid cancer

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