Production of biomass and bioactive compounds from adventitious roots by optimization of culturing conditions of Eurycoma longifolia in balloon-type bubble bioreactor system

Tao, Lu-Lu; Park, Soyoung; Ibrahim, Rusli; Paek, Kee-Yoeup

doi:10.1016/j.jbiosc.2014.11.010

Cited by 42 publications

(24 citation statements)

References 30 publications

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“…For instance, exogenous IAA reduces the herbivory-induced accumulation of nicotine and jasmonates (Baldwin et al, 1997;Baldwin, 1989), gene expression of jasmonate-dependent proteinase inhibitors genes (Kernan and Thornburg, 1989), and vegetative storage proteins (DeWald et al, 1994;Liu et al, 2005). Conversely, IAA promotes the production of phenolics and flavonoids in root cell cultures in a dose-dependent manner (Lulu et al, 2015;Mahdieh et al, 2015) and the auxin homolog 2,4-dichlorophenoxyacetic acid acts as a strong inducer of defense responses in rice (Oryza sativa; Xin et al, 2012;Song, 2014).…”

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confidence: 99%

Auxin Is Rapidly Induced by Herbivore Attack and Regulates a Subset of Systemic, Jasmonate-Dependent Defenses

et al. 2016

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Plant responses to herbivore attack are regulated by phytohormonal networks. To date, the role of the auxin indole-3-acetic acid (IAA) in this context is not well understood. We quantified and manipulated the spatiotemporal patterns of IAA accumulation in herbivore-attacked Nicotiana attenuata plants to unravel its role in the regulation of plant secondary metabolism. We found that IAA is strongly, rapidly, and specifically induced by herbivore attack. IAA is elicited by herbivore oral secretions and fatty acid conjugate elicitors and is accompanied by a rapid transcriptional increase of auxin biosynthetic YUCCA-like genes. IAA accumulation starts 30 to 60 s after local induction and peaks within 5 min after induction, thereby preceding the jasmonate (JA) burst. IAA accumulation does not require JA signaling and spreads rapidly from the wound site to systemic tissues. Complementation and transport inhibition experiments reveal that IAA is required for the herbivore-specific, JA-dependent accumulation of anthocyanins and phenolamides in the stems. In contrast, IAA does not affect the accumulation of nicotine or 7-hydroxygeranyllinalool diterpene glycosides in the same tissue. Taken together, our results uncover IAA as a rapid and specific signal that regulates a subset of systemic, JA-dependent secondary metabolites in herbivore-attacked plants.

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confidence: 99%

Auxin Is Rapidly Induced by Herbivore Attack and Regulates a Subset of Systemic, Jasmonate-Dependent Defenses

et al. 2016

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“…In balloontype bubble bioreactor system, the average of increasing biomass was 13.1 fold higher than initial inoculum and was almost 2 fold higher than temporary immersion system. Root biomass was also found to be higher in the bioreactor cultures than in the shake flask culture of Astragalus membranaceus (Wu et al, 2011) and Eurycoma longifolia (Lulu et al, 2015). In medium supplemented with sucrose 50 g/L adventitious roots growth rate was highest.…”

Section: Resultsmentioning

confidence: 87%

“…Liquid culture systems have significant effects on multiplication rates and morphology of shoots, somatic embryos, microtubers or bulblets produced in vitro (Hvoslef-Eide & Preil, 2005). Many researches have been developed to produced adventitious roots in liquid culture, such as production of biomass and bioactive compounds from adventitious roots of Eurycoma longifolia in ballon-type buble bioreactor system (Lulu et al, 2015), establishment of adventitious root culture of Stevia reboudiana Bertoni in a roller bottle system (Reis et al, 2011), production of biomass and bioactive compounds of Panax ginseng adventitious root in ballon-type bubble bioreactor (Wang et al, 2013), and production of biomass and metabolites accumulation in adventitious root culture of Glycyrhiza uralensis Fisch (Yin et al, 2014). In many cases, cultivation of roots in liquid culture have faster growth rate than in agar medium, such as growth rate of Justicia gendarussa hairy root (Wahyuni et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Biomass Production of Gynura procumbens Adventitious Roots in Different Type of Liquid Culture

et al. 2017

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Gynura procumbens has a potency to produce raw material for pharmaceutical industry. Liquid culture systems have significant effects on multiplication rates of organ, so the propagation technology to increase biomass of this plant or organ using the liquid culture system was necessary. This research was conducted to compare biomass production of adventitious roots of G. procumbens in different liquid culture (shake flask, temporary immersion bioreactor and balloon-type bubble bioreactor). Adventitious roots culture was maintained in Murashige and Skoog liquid medium supplemented with IBA (indole butyric acid) 5 mg/L and different concentrations of sucrose (10, 30, 50 g/L). Result showed that the highest biomass production (fresh weight) was in shake flask that was 3.9-fold higher than initial explant, while in temporary immersion system was 5.12-fold higher than initial explant, and in balloon- type bubble bioreactor was 13.1-fold higher than initial explant. The highest enhancement of adventitious roots was occurred at sucrose supplementation of 50 g/L. Based on this research we found that the best type of liquid culture to increase biomass of G. procumbens adventitious roots was balloon-type bubble bioreactor. Scaling-up of adventitious root culture are necessary to fulfill the need of raw material for pharmaceutical industry and ballon-type bubble bioreactor was the most suitable method to scale up the performance.

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“…Development of large-scale culture methods using bioreactors has opened up feasibilities of production of SMs at the industrial level [364]. The scale-up of in vitro adventitious root cultures of Morinda citrifolia, Eurycoma longifolia, Echinacea purpurea, Hypericum perforatum, and Panax ginseng by applying 20 L-10,000 L bioreactors for mass production of economically important SMs has been reported [335,348,350,361,[364][365][366][367][368][369]. In the present review, we summarize some of case studies in this field.…”

Section: Sm Production In Untransformed Root Culturesmentioning

confidence: 99%

Morphogenesis, Genetic Stability, and Secondary Metabolite Production in Untransformed and Transformed Cultures

Halder¹,

Jha²

2020

Reference Series in Phytochemistry

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In addition to the primary metabolites, plants produce a vast number of chemically diversified economically valuable secondary metabolites (SMs) in specific cell types or tissue or organ of phylogenetically related family or genus or species or even to a single chemical race under tight environmental, developmental, and genetic control. Some SMs such as morphine and codeine are only synthesized in a particular organized and differentiated tissue or organ.

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Production of biomass and bioactive compounds from adventitious roots by optimization of culturing conditions of Eurycoma longifolia in balloon-type bubble bioreactor system

Cited by 42 publications

References 30 publications

Auxin Is Rapidly Induced by Herbivore Attack and Regulates a Subset of Systemic, Jasmonate-Dependent Defenses

Auxin Is Rapidly Induced by Herbivore Attack and Regulates a Subset of Systemic, Jasmonate-Dependent Defenses

Biomass Production of Gynura procumbens Adventitious Roots in Different Type of Liquid Culture

Morphogenesis, Genetic Stability, and Secondary Metabolite Production in Untransformed and Transformed Cultures

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