“…The distribution of these ⌬V, which correspond to avalanches reaching the alveoli, should follow a power law (32,33). Additionally, because airway opening is also associated with crackle sound generation (2,6,8,23,25,27), we expect that the density of crackles is highest near the lower knee of the P-V curve. To test these predictions, we measured P-V loops in normal isolated dog lung lobes during inflation from the collapsed state to total lobe capacity.…”