Processing, properties, and in vitro bioactivity of polysulfone‐bioactive glass composites

Abstract

The mismatch between the mechanical properties of bioceramics and natural tissue has restricted in several cases a wider application of ceramics in medical and dental fields. To overcome this problem, polymer matrix composites can be designed to combine bioactive properties of some bioceramics with the superior mechanical properties of some engineering plastics. In this work, polymer particulate composites composed of a high mechanical-property polymer and bioactive glass particles were produced and both the in vitro bioactivity and properties of the system were investigated. Composites with different volume fraction and particle size were prepared. In vitro tests showed that hydroxy-carbonate-apatite can be deposited on the surface of a composite as early as 20 h in a simulated body fluid. Ionic evolution from a composite with 40% volume fraction of particles was demonstrated to be similar to bulk bioactive glasses. The mechanical properties of some of the obtained composites had values comparable with the ones reported for bone. Moreover, a physical model based on dynamical mechanical tests showed evidences that the interface of the composite was aiding in the stress transfer process.

Evaluation of the interactions between collagen and the surface of a bioactive glass during in vitro test

“…Raw materials were introduced into a platinum crucible and melted at 13008C for 12 h. The glass melt was then cast into optically polished graphite molds to yield discs. An in vitro test in SBF (Simulated Body fluid that has ionic composition similar to blood 22 ) was performed by suspending different disks in the solution (surface area of the sample/volume of solution 5 0.1 cm 21 ) for the desired period of time. The solutions with the suspending samples were kept in a temperature controlled water bath at 378C.…”

Nanocomposite and Nanostructured Carbon-based Films as Growth Substrates for Bone Cells

“…For example, PTFE/PVDF/PP has been tested as a material for septal nasal reconstruction (Scierski et al, 2007). PSU was used for the creation of composites with bioactive glass particles for potential bone and cartilage tissue engineering (Zhang et al, 2002;Orefice et al, 2007) or for fabrication of bone joint screws (Jan & Grzegorz 2005).…”

In Vitro Bioactivity Study of Pure Wollastonite Prepared from Local Raw Materials

“…The formation mechanism of apatite was proposed by Hench et al [32]. The exchange of calcium ions in pseudowollastonite with H + in SBF solution gives rise to the formation of silanol (Si-OH) in the surface layer, an increase in pH value at the pseudowollastonite-SBF, and eventually, to the production of a negatively charged surface with the functional group (Si-O − ).…”