V.I. Vernadsky’s work "The Beginning and Eternity of Life" (1922), as well as his other scientific works, made a significant contribution to the development of many branches of natural history. It fundamentally changed the scientific worldview of the twentieth century. This work determined the place of man and his scientific thought in the evolution of the biosphere, made it possible to take a fresh look at the surrounding nature as the environment of human existence. It posed many actual problems and outlined ways to solve them in the future. The combination of deep knowledge in various industries with the history of their development determined the formation of V. I. Vernadsky's views on science as a specific natural phenomenon inherent to the genus Homo sapiens. He considered the progress of science as the natural process of the development of human thought, aimed at the cognition of the laws of nature and the laws of its own development. V. I. Vernadsky has analyzed various mechanisms of the origin of life and came to the conclusion that life could be eternal and had no beginning. He emphasizes two geologically most important points: firstly, the planetary, geologically regular nature of life; secondly, the close connection of all geological processes in the biosphere with the activity of living matter. Consequently, the understanding of life as a planetary phenomenon led V. I. Vernadsky to an understanding of the direct dependence of the existence of the biosphere on the conditions caused by geological processes.