Primary T-cell Immunoblastic Lymphoma of the Orbit in a Pediatric Patient

Non-Hodgkins lymphoma presenting with proptosis in an infant

“…Although malignant lymphomas frequently cause orbital tumors in adults, there are only individual case reports of childhood orbital involvement by B, 2 T, 3 and null cell 4 lymphomas. Although non-Hodgkin's lymphoma accounts for 3% of cancers in patients younger than 5 years old, 5 orbital lymphoma as part of systemic nodal disease in children is generally rare 6 and in infants hitherto unreported as a cause of proptosis.…”

Ocular and Adnexal Lymphoma

“…Ferry et al studied 353 cases of ocular adnexal lymphoma and found only two cases of T-cell origin . In addition to this case, only a few other cases of primary adnexal T-cell lymphoma have been reported (Hirasaka et al 1992 ;Leidenix et al 1993 ;Lee et al 2006 ;Janatpour et al 2007 ;Chen et al 2009 ;Amit et al 2012 ), with two of the cases being diagnosed in young children (Leidenix et al 1993 ;Amit et al 2012 ). Although rare, T-cell neoplasm can affect all the ocular and adnexal tissues that B-cell lymphoma does, including intraocular tissues and ocular adnexa (the eyelids, conjunctiva, orbit, extraocular muscles, or lacrimal gland).…”

Primary orbital non-Hodgkin's lymphoma

“…This paper describes a case of primary orbital peripheral T-cell lymphoma in a 6-year-old girl, a very unusual occurrence at this age. Leidenix et al 12 reported a case of primary T-cell lymphoma confined to the orbit in a paediatric patient. The patient received surgical excision, systemic chemotherapy and local radiation and died of dissemination of disease.…”