Primary retroperitoneal liposarcoma with extensive ossification

Abstract

Rationale: Primary retroperitoneal liposarcoma, which originates from mesenchymal tissues, can rarely present with extensive ossification. Patient concerns: A 41-year-old male patient presented with a chief complaint of discomfort around the waist for 2 months. Diagnoses: Computerized tomography (CT) and magnetic resonance imaging suggested a lesion of approximately 5.6 × 5.1 × 8.7 cm in front of the psoas major muscle, which was considered to be a mesenchymal or neurogenic tumor. Interventions: The hard mass was removed by laparotomy, and the pathological investigation revealed that this was an atypical lipomatous tumor/well-differentiated liposarcoma, with extensive ossification. Outcomes: The patient was discharged from the hospital after surgery. There was no sign of reoccurrence after 1 year of follow-up. Lessons: Retroperitoneal liposarcomas with extensive ossification are rare tumors that can present with nonspecific symptoms, and are difficult to diagnose. CT is the most common imaging technique, and surgical resection has been considered to be the most effective treatment. This rare case can be challenging for diagnosis and treatment.

A Case of a Giant Liposarcoma at Binh Dan Hospital

“…These giant liposarcomas most frequently manifest between the ages of 60 and 70. The incidence rate of RLSs is roughly equal among genders [ 3 ]. The definitive diagnostic tools for all cases are CT or magnetic resonance imaging (MRI) [ 3 ].…”

“…The incidence rate of RLSs is roughly equal among genders [ 3 ]. The definitive diagnostic tools for all cases are CT or magnetic resonance imaging (MRI) [ 3 ].…”

“…Liposarcomas, accounting for 25%, are the most prevalent type of sarcoma found in the retroperitoneum, succeeded by leiomyosarcomas and undifferentiated pleomorphic sarcomas [ 2 ]. These tumors can develop at any age, but they most commonly occur during the sixth and seventh decades of life and show no significant preference for gender or race [ 3 ]. The vast potential space in the retroperitoneum allows liposarcomas to reach considerable sizes before compressing nearby structures and causing symptoms [ 4 ].…”

Primary retroperitoneal liposarcoma: a rare case report

“…5 Primary retroperitoneal liposarcoma (PRPLS) occurs mainly in patients aged 60 to 70 years, with no sex predominance. 6 In the present study, we report a 34-year-old female patient with PRPLS who successfully underwent surgical resection. In addition, the clinical and pathological characteristics, diagnosis, and treatment methods of PRPLS were summarized.…”