Primary primitive neuroectodermal tumor of the lung.

Catalan, Robert; Murphy, Timothy P.

doi:10.2214/ajr.169.4.9308502

Cited by 19 publications

(4 citation statements)

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“…In conclusion, primary pulmonary ES/PNET is a very rare tumor, and bilateral multiple intrapulmonary metastases is an extremely rare manifestation of this disease. To date in the English literature, of twenty previously reported cases, only two had pulmonary metastases [7,8]. This is the third report of primary pulmonary ES/PNET with bilateral multiple intrapulmonary metastases without pleural or chest wall involvement.…”

Section: Discussionmentioning

confidence: 69%

Primary Pulmonary Ewing’s Sarcoma / Primitive Neuroectodermal Tumor (ES/PNET) Case

Yücel¹

2016

Ann Clin Anal Med

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ÖzetEwing Sarkomu /Primitif Nöroektodermal Tümörler (ES/PNET) çocuk ve adölesan-larda osteosarkomdan sonra görülen 2. en sık primer malign kemik tümörleridir.Genellikle ekstremitelerin uzun kemiklerinde görülürler. Primer pulmoner ES/PNET çok nadirdir ve literatürde sadece olgu sunumları şeklinde bildirilmiştir. 24 yaşın-daki erkek hastamızın bilateral multipl pulmoner kitle ve nodülü mevcuttu ve yapılan transtorasik biyopsi sonucu ES/PNET olarak değerlendirildi. Pozitron Emisyon Tomografi/Bilgisayarlı Tomografi ve tüm vücut kemik sintigrafisi ile vücudu-nun başka bir alanında primer odak saptanmayan olgumuz primer pulmoner ES/ PNET' in, bilateral multipl pulmoner metastazı olarak kabul edildi. Bugüne kadar literatürde sadece yirmi primer pulmoner ES/PNET olgusu ve iki tane pulmoner metastaz olgusu bildirilmiştir. Bu olgu primer pulmoner ES/PNET'in bilateral multipl pulmoner metastazla seyreden üçüncü olgusu olması nedeni ile sunulmuştur. Anahtar KelimelerEwing Sarkomu; Primitif Nöroektodermal Tümör; Multipl Pulmoner Nodüller AbstractEwing Sarcoma/Primitive neuroectodermal tumor (ES/PNET) is the second most common primary malignant bone tumor, following osteosarcoma, in children and adolescents, most often arising in long bones. Primary pulmonary ES/PNET is very rare and is seen only as case reports in the literature. Here, we report on a 24-year-old man who had bilateral multiple pulmonary masses and nodules on a chest X-ray. By transthoracic biopsy he was diagnosed with ES/PNET. Since no other primary focus was determined in his Positron Emission TomographyComputed Tomography and total body bone scan, the patient was accepted as primary pulmonary ES/PNET. To our knowledge only twenty cases have been described in the English literature and of them only two had intrapulmonary multiple metastases. We present this case because he will be the third reported ES/PNET case which has been seen with bilateral multiple pulmonary metastases.

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Section: Discussionmentioning

confidence: 69%

Primary Pulmonary Ewing’s Sarcoma / Primitive Neuroectodermal Tumor (ES/PNET) Case

Yücel¹

2016

Ann Clin Anal Med

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“…Catalan and Murphy reported on a 29-year-old man with PNET of the lung [8]. The chest radiographs showed a left pleural effusion and probable opacity in the left lower lobe.…”

Section: Discussionmentioning

confidence: 99%

Primary pulmonary primitive neuroectodermal tumor: CT and skeletal scintigraphic image features with pathologic correlation (2006: 6b)

et al. 2006

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We describe a rare case of a primitive neuroectodermal tumor (PNET) originating in the lung of a 28-year-old woman. A lung mass was detected incidentally on a chest radiograph taken before a Caesarian delivery. The chest P-A view showed a well-defined, lobulated mass in the right lower lobe with a small pleural effusion on the right. A thoracic CT with contrast enhancement showed a lobulated, heterogeneous, enhanced mass of approximately 9.2 x 8.4 x 6.3 cm with inner amorphous calcifications in the right lower lobe and a small right pleural effusion. A right lower lobectomy was performed 1 month after delivery. The pathology report was a primary pulmonary PNET with focal visceral pleural involvement.

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“…The thoracic region is the most common site for recurrent disease, manifested as local chest wall recurrence or pulmonary metastasis. The next most common area involves skeletal, brain, liver, and adrenal glands metastasis (Catalan and Murphy, 1997). In English literature, only eight cases of primary lung PNET have been reported, five of them with follow‐up.…”

Section: Introductionmentioning

confidence: 99%

“…In English literature, only eight cases of primary lung PNET have been reported, five of them with follow‐up. Of the five patients, only one developed widespread metastasis in the right lung, left adrenal gland and right ovary (Catalan and Murphy, 1997; Imamura et al , 2000; Kahn et al , 2001).…”

Section: Introductionmentioning

confidence: 99%

Mouth metastasis of peripheral primitive neuroectodermal tumor

et al. 2005

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We describe a case of oral metastasis of peripheral primitive neuroectodermal tumor (pPNET) in a 68-year-old man, who presented the primary lesion in the chest. Oral metastasis of pPNETs is very rare and we have not found any similar case reported in the English literature. Clinical examination showed an extensive and ulcerated fleshy mass measuring 3.0 x 3.5 cm in the right lower gingivae. Microscopic examination showed sheets of proliferating small, hyperchromatic, round cells. Tumor cells were reactive to neuron-specific enolase (NSE), vimentin and MIC-2 gene by immunohistochemistry, consistent with PNET. The patient died 3 weeks later because of respiratory insufficiency.

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Primary primitive neuroectodermal tumor of the lung.

Cited by 19 publications

References 0 publications

Primary Pulmonary Ewing’s Sarcoma / Primitive Neuroectodermal Tumor (ES/PNET) Case

Primary Pulmonary Ewing’s Sarcoma / Primitive Neuroectodermal Tumor (ES/PNET) Case

Primary pulmonary primitive neuroectodermal tumor: CT and skeletal scintigraphic image features with pathologic correlation (2006: 6b)

Mouth metastasis of peripheral primitive neuroectodermal tumor

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