2005
DOI: 10.1111/j.1601-0825.2004.01027.x
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Mouth metastasis of peripheral primitive neuroectodermal tumor

Abstract: We describe a case of oral metastasis of peripheral primitive neuroectodermal tumor (pPNET) in a 68-year-old man, who presented the primary lesion in the chest. Oral metastasis of pPNETs is very rare and we have not found any similar case reported in the English literature. Clinical examination showed an extensive and ulcerated fleshy mass measuring 3.0 x 3.5 cm in the right lower gingivae. Microscopic examination showed sheets of proliferating small, hyperchromatic, round cells. Tumor cells were reactive to n… Show more

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Cited by 8 publications
(3 citation statements)
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“…Central PNET such as medulloblastoma originates in the brain and spinal cord, whereas pe ripheral PNETs include adrenal and extra-adrenal neuroblastomas of soft tissues, nerve, and bone. The peripheral Primitive Neuroectodermal Tu mor was first recognized by Arthur Purdy Stout in 1918 as a member of the family of "small roundcell tu mors" which was subsequently designated as PNET [8].…”
Section: Discussionmentioning
confidence: 99%
“…Central PNET such as medulloblastoma originates in the brain and spinal cord, whereas pe ripheral PNETs include adrenal and extra-adrenal neuroblastomas of soft tissues, nerve, and bone. The peripheral Primitive Neuroectodermal Tu mor was first recognized by Arthur Purdy Stout in 1918 as a member of the family of "small roundcell tu mors" which was subsequently designated as PNET [8].…”
Section: Discussionmentioning
confidence: 99%
“…The term was first used to describe a group of embryonal tumours located in the central nervous system (cPNET), which were also described as medulloblastomas and medulloepitheliomas. More recently, the PNET concept has been expanded to include histologically similar, but peripherally located, tumours, referred to as peripheral primitive neuroectodermal tumours (pPNETs) (Pereira et al, 2005). The tumours have been described at various sites in children and adults, but only one case has been reported previously in the hand in an adult (Harder et al, 2003).…”
Section: Discussionmentioning
confidence: 99%
“…The peripheral Primitive Neuroectodermal Tumor first recognized by Arthur Purdy Stout 9 in 1918, is a member of the family of "small round-cell tumors" this was subsequently designated as PNET. It is seen involving any bone, however it predominately involves central and axial skeleton as well as the diaphysis of long bones.…”
Section: Discussionmentioning
confidence: 99%