Primary Neoplasms of the Salivary Glands in Animals Compared to Similar Tumors in Man

Koestner, A.; Buerger, Leopold

doi:10.1177/030098586500200301

Cited by 34 publications

(38 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The neoplasm was determined to have arisen from a minor or accessory salivary gland. These tumours have been occasionally described in the cat (KOESTNER and BUERGER, 1965;SPANGLER and CULBERTSON, 1991). Metastasis has not been described, to our knowledge, in association with a neoplasm derived from a minor salivary gland in the cat.…”

Section: Discussionmentioning

confidence: 73%

Metastatic Adenocarcinoma of a Minor Salivary Gland in a Cat

Burek¹,

Munn²,

Madewell³

1994

Journal of Veterinary Medicine Series A

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 73%

Metastatic Adenocarcinoma of a Minor Salivary Gland in a Cat

Burek¹,

Munn²,

Madewell³

1994

Journal of Veterinary Medicine Series A

View full text Add to dashboard Cite

show abstract

“…There is a report [9] of three benign mixed salivary tumors and one malignant salivary tumor in the dog that appeared to have the potential to produce cartilage and bone. Tables I and I1 show the distribution of cases in the first year of the registry.…”

Section: Resultsmentioning

confidence: 99%

Classification of Epithelial Canine Mammary Tumors in a Defined Population

et al. 1977

View full text Add to dashboard Cite

Abstract. Ductal carcinomas accounted for nearly all metastases seen in epithelial canine mammary tumors submitted to the Tulsa Registry of Canine and Feline Neoplasms in a 4-year period from a defined canine population. Lobular and squamous cell carcinomas were the only other metastatic carcinomas seen. Early ductal carcinoma was used to indicate nonmetastatic ductal carcinoma with a favorable post-surgical prognosis. Benign epithelial tumors were categorized as adenoma, ductal papilloma and squamous cell papilloma. Progressive transformation of well defined adenomas and papillomas to carcinoma was not evident in histologic preparations.Squamous metaplasia was seen in many ductal papillomas and ductal carcinomas. Inclusion of pseudocartilage and pseudoosteoid and osteoid, cartilage and bone with ductal carcinomas, adenomas and ductal papillomas seemed related to secretions escaping from neoplastic epithelial cells into stroma or between proliferating tumor cells. There was proliferation and perhaps even neoplastic transformation of myoepithelial cells in some of these tumors. Changes in myoepithelium, however, appeared to be secondary to neoplastic transformation of epithelium. Bone and cartilage in these tumors were considered heterotopic with no neoplastic potential.

show abstract

“…9 Numerous types of salivary-gland tumors have been reported, as have various classification schemes. 3,5,8,10 One recent review classified tumors as adenocarcinoma, carcinoma, squamous-cell carcinoma, mixed, primary fibrosarcoma, mast-cell tumor, adenoma, and unspecified. 3 Other studies have included mucoepidermoid, acinic cell, malignant mixed, true malignant mixed, malignant melanoma, secondary fibrosarcoma, and secondary lymphosarcoma.…”

mentioning

confidence: 99%

Extraskeletal Osteosarcoma of the Mandibular Salivary Gland in a Dog

Thomsen¹,

Myers²

1999

Vet Pathol

View full text Add to dashboard Cite

Abstract. A 14-year-old spayed female shepherd/collie crossbred dog had a 6 ϫ 4-cm mass excised from below the right ear. The partially encapsulated, neoplastic mass had a necrotic core and was embedded in the mandibular salivary gland. Histologically, the mass was composed of numerous multinucleate giant cells and large, oval, pleomorphic cells that produced osteoid. Neoplastic cells were immunoreactive for vimentin and actin but not for keratin, desmin, or S-100 protein. At postmortem examination 1 month later, an 11-cm spherical mass had recurred at the surgical site, and there were metastatic nodules in the lungs, ipsilateral mandibular lymph nodes, and kidney. The tumor was diagnosed as an osteosarcoma of the mandibular salivary gland with pulmonary, lymphatic, and renal metastasis. In addition, a 17-year survey of canine salivary-gland neoplasms revealed that most were adenocarcinomas or carcinomas.Key words: Dogs; immunohistochemistry; osteosarcoma; salivary gland neoplasms.Salivary-gland neoplasms and extraskeletal osteosarcomas are both rare in dogs. 3,9,10 Salivary neoplasms make up 0.09% of all canine surgical biopsies in one report. 3 Extraskeletal osteosarcomas have been reported to make up approximately 1% of all canine osteosarcomas. 9 Numerous types of salivary-gland tumors have been reported, as have various classification schemes. 3,5,8,10 One recent review classified tumors as adenocarcinoma, carcinoma, squamous-cell carcinoma, mixed, primary fibrosarcoma, mast-cell tumor, adenoma, and unspecified. 3 Other studies have included mucoepidermoid, acinic cell, malignant mixed, true malignant mixed, malignant melanoma, secondary fibrosarcoma, and secondary lymphosarcoma. 5,8,10,13 Bone has been reported in mixed tumors (pleomorphic adenomas), malignant mixed tumors (carcinoma in pleomorphic adenomas), and true malignant mixed tumors (carcinosarcomas). 2,4,6,13 The vast majority of salivary-gland tumors are adenocarcinomas and carcinomas according to our study and others. 3,10 Extraskeletal osteosarcomas have been reported as primary tumors in a variety of soft tissues, but not in salivary glands. 9 In this paper, we present histopathologic and immunohistochemical evidence of a malignant mandibular salivary-gland tumor that consisted only of an osteosarcoma, and we briefly summarize 43 cases of additional canine salivary-gland tumors.An excisional biopsy was submitted in 10% neutral buffered formalin to the Iowa State University College of Veterinary Medicine, Department of Veterinary Pathology, from a 14-year-old spayed female shepherd/collie crossbred dog. The rapidly growing mass had been known to be present for approximately 2 weeks before being surgically removed. It was described as hard, fixed, encapsulated, vascular, and originating ventral to the right ear and extending under the mandible. Grossly, the surface of the oval mass was light gray, rough, and fibrous, measuring 6 cm long and 4 cm in diameter. A tan, lobulated, glandular structure (mandibular salivary gland) was embedded in the ne...

show abstract

Primary Neoplasms of the Salivary Glands in Animals Compared to Similar Tumors in Man

Cited by 34 publications

References 7 publications

Metastatic Adenocarcinoma of a Minor Salivary Gland in a Cat

Metastatic Adenocarcinoma of a Minor Salivary Gland in a Cat

Classification of Epithelial Canine Mammary Tumors in a Defined Population

Extraskeletal Osteosarcoma of the Mandibular Salivary Gland in a Dog

Contact Info

Product

Resources

About