Primary Malignant Melanoma of the Penis. Two Cases and a Review of the Literature

Khezri, Abdolaziz; Dounis, A.; Roberts, Julian

doi:10.1111/j.1464-410x.1979.tb02850.x

Cited by 29 publications

(6 citation statements)

References 11 publications

(2 reference statements)

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“…6 An appreciable risk of recurrence in the penile stump after partial amputation led to the suggestion that, for lesions of the glans, total amputation with block dissection of inguinal nodes would be more justified. Of eight patients who were treated by total amputation, four were alive after five years.…”

Section: Discussionmentioning

confidence: 99%

Malignant melanoma of prepuce: case report.

Forrer¹,

Sugrue²

1986

Sexually Transmitted Infections

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Section: Discussionmentioning

confidence: 99%

Malignant melanoma of prepuce: case report.

Forrer¹,

Sugrue²

1986

Sexually Transmitted Infections

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“…As anastomoses are common in the lymphatic network of the penis, a lesion may metastasize either contralaterally or bilaterally so bilateral elective lymph node dissection is not recommended in these patients. Nevertheless, some authors suggest that there may be appreciable risk of local recurrence in the penile stump after partial amputation of the penis, so for lesions on the glans, total amputation with block dissection of inguinal nodes is justified [27,29,30,33,34]. The small series reported here would not support this radical approach.…”

Section: Penile Melanomamentioning

confidence: 67%

Rare variants of malignant melanoma

Milton

Shaw

1992

World j. surg.

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The personal experience with 5 rare types of malignant melanoma is reviewed to point out some of the practical problems in the diagnosis and management of these tumors. The rare forms discussed are conjunctival, nasal, oral, vulvar, and penile melanomas. All pigmented lesions in the oral cavity, but not the penis or vulva, should be prophylactically excised as lesions in the mouth have a higher malignant potential. Local excision of all 5 forms of primary melanomas, no matter how locally advanced they may be, is the sole treatment. Nevertheless, anatomic constraints often preclude surgery with generous margins and consequently local recurrence, particularly for conjunctival, nasal, and oral primary lesions, is usually the major first failure in treatment. Lymph node dissection is only performed if the regional nodes are palpable at the time of first presentation. Elective lymph node dissections are not performed since the patients are often elderly, the lymphatic drainage is usually ambiguous or multiple, and the disease tends to spread hematogenously rather than lymphatically. Surgery still remains the cornerstone of treatment for these rare forms of melanoma but prognosis is very poor since surgery is often a palliative rather than a curative measure. Improved survival may depend on identifying more effective chemotherapeutic and immunologic agents.

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“…So they recommended that all genital reported. The glans is involved most commonly, as in 23 of 28 cases reported by Khezei et al (9), with not infrequent extension into the meatus. Less frequently, the lesion may be found on the prepuce «10%) and 3 cases involving the skin of the shaft have been reported (10).…”

Section: Discussionmentioning

confidence: 86%