Malignant melanoma of prepuce: case report.

Forrer, Ja; Sugrue, D L

doi:10.1136/sti.62.6.399

Cited by 4 publications

(5 citation statements)

References 5 publications

(1 reference statement)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The median age of the SMU patients with glans penis melanoma correlates well with other previous reports 5 , 7 , 10 , 36 and all six lesions arose de novo on the glans as in other series 5 , 7 , 10 , 35 –39 . Unlike other reports, however, no patient stated that the lesion had started as a long‐standing pigmented naevus 5 , 7 , 37 , 39 . Several studies have suggested possible reasons for the delay in diagnosis 5 , 35 , 36 .…”

Section: Discussionsupporting

confidence: 91%

“…Sometimes the patient is reticent about seeking medical advice through fear of possible malignancy. As the clinical presentation of this rare lesion can be misleading and its benign or malignant nature may not be determined accurately on the basis of clinical findings alone, 7 the lesion may be misdiagnosed as inflammatory or infectious.…”

Section: Discussionmentioning

confidence: 99%

“…Reports of mucosal melanomas are sporadic and small in terms of patient numbers. This dearth of clinical information is partially responsible for the fact that insights into their epidemiology, pathogenesis, natural history and treatment have not kept pace with advances in knowledge about cutaneous melanomas 1 –11 . The present study was undertaken to document the overall experience of the Sydney Melanoma Unit (SMU) in treating patients with mucosal and glans penis melanomas.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Primary Mucosal and Glans Penis Melanomas: The Sydney Melanoma Unit Experience

Larsson

Shaw

Thompson

et al. 1999

Aust. N.Z. J. Surg.

View full text Add to dashboard Cite

Possible reasons for poor survival include: (i) non-specific symptoms resulting in late presentation; (ii) locally advanced disease not being recognized by a clinician as a rare form of melanoma, resulting in a delay in treatment; (iii) anatomical constraints precluding surgery with generous margins and consequently resulting in a high incidence of local recurrence. Also, rich vascularity and multiple lymphatic drainage pathways may mean a predisposition to early dissemination. Prompt diagnosis and referral to a specialist unit for treatment and follow up are essential. Adequate surgery remains the cornerstone of treatment for these types of melanoma until more effective systemic therapies become available.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Primary Mucosal and Glans Penis Melanomas: The Sydney Melanoma Unit Experience

Larsson

Shaw

Thompson

et al. 1999

Aust. N.Z. J. Surg.

View full text Add to dashboard Cite

show abstract

“…As anastomoses are common in the lymphatic network of the penis, a lesion may metastasize either contralaterally or bilaterally so bilateral elective lymph node dissection is not recommended in these patients. Nevertheless, some authors suggest that there may be appreciable risk of local recurrence in the penile stump after partial amputation of the penis, so for lesions on the glans, total amputation with block dissection of inguinal nodes is justified [27,29,30,33,34]. The small series reported here would not support this radical approach.…”

Section: Penile Melanomamentioning

confidence: 67%

Rare variants of malignant melanoma

Milton

Shaw

1992

World j. surg.

View full text Add to dashboard Cite

The personal experience with 5 rare types of malignant melanoma is reviewed to point out some of the practical problems in the diagnosis and management of these tumors. The rare forms discussed are conjunctival, nasal, oral, vulvar, and penile melanomas. All pigmented lesions in the oral cavity, but not the penis or vulva, should be prophylactically excised as lesions in the mouth have a higher malignant potential. Local excision of all 5 forms of primary melanomas, no matter how locally advanced they may be, is the sole treatment. Nevertheless, anatomic constraints often preclude surgery with generous margins and consequently local recurrence, particularly for conjunctival, nasal, and oral primary lesions, is usually the major first failure in treatment. Lymph node dissection is only performed if the regional nodes are palpable at the time of first presentation. Elective lymph node dissections are not performed since the patients are often elderly, the lymphatic drainage is usually ambiguous or multiple, and the disease tends to spread hematogenously rather than lymphatically. Surgery still remains the cornerstone of treatment for these rare forms of melanoma but prognosis is very poor since surgery is often a palliative rather than a curative measure. Improved survival may depend on identifying more effective chemotherapeutic and immunologic agents.

show abstract

“…Patients are sometimes reticent about seeking medical advice due to fear of malignancy. Since the clinical presentation of this rare lesion can be misleading and its benign versus malignant nature may not be determined accurately on the basis of clinical findings alone 16 , the lesion can be misdiagnosed as inflammatory or infectious.…”

Section: Case Reportmentioning

confidence: 99%

Melanoma de Pênis Tratado Conservadoramente: Relato de Caso e Revisão da Literatura

Ornellas¹,

Quirino²,

Wisnescky³

et al. 2007

Rev. Bras. Cancerol.

View full text Add to dashboard Cite

Melanomas do pênis são tumores malignos muito agressivos. Descrevemos o caso de um paciente com uma lesão confinada ao prepúcio e com linfonodos inguinais clinicamente negativos, tratados conservadoramente. O paciente submeteu-se à ressecção alargada da lesão para tratamento e diagnóstico. O tratamento das regiões inguinais em pacientes com melanoma de pênis permanece controvertido, uma vez que a incidência de doença metastática é significativamente mais baixa nos pacientes com estádios patológicos iniciais. Como nesse paciente o estádio patológico do melanoma de pênis era T2a (profundidade 1,9 mm, sem ulceração), decidimos usar linfocintigrafia pré-operatória, mapeamento intra-operatório dos linfonodos e biópsia do linfonodo sentinela para avaliar o comprometimento metastático inguinal. Cortes de congelação do linfonodo sentinela direito retirado foram negativos para malignidade e nenhum tratamento adjuvante foi realizado. A ressecção alargada da lesão permitiu efetivo controle local do tumor peniano e o paciente é mantido em acompanhamento clínico pós-operatório.

show abstract

Malignant melanoma of prepuce: case report.

Abstract: SUMMARY A 58 year old man presented with what seemed to be a simple penile lesion, but which on subsequent histological examination proved to be a malignant melanoma. The lesion was excised by circumcision. No further treatment was considered to be necessary.

Cited by 4 publications

References 5 publications

Primary Mucosal and Glans Penis Melanomas: The Sydney Melanoma Unit Experience

Primary Mucosal and Glans Penis Melanomas: The Sydney Melanoma Unit Experience

Rare variants of malignant melanoma

Melanoma de Pênis Tratado Conservadoramente: Relato de Caso e Revisão da Literatura

Contact Info

Product

Resources

About