Primary Malignant Fibrous Histiocytoma of the Pleura

Cho, Kyung Hwa; Park, Chul; Hwang, Ki-Eun; Hwang, Yu Ri; Seol, Chang Hwan; Choi, Keum Ha; Lee, Mi Kyung; Choi, Soon Ho; Kim, Hak Ryul; Jeong, Eun Taik

doi:10.4046/trd.2013.74.5.222

Cited by 3 publications

(4 citation statements)

References 9 publications

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“…In the present case, the patient did not complain of pain. Histologically, undifferentiated pleomorphic sarcoma is characterized by the presence of spokes of a wheel-like structure, showing spindle-shaped cells such as fibrocytes and histiocytes arranged in a storiform pattern 3 , 5 , 14 . Numerous giant cells show eosinophilic cytoplasm on staining; single or multiple irregular nuclei are observed, with inflammatory cells often mixing with the tumor cells 13 .…”

Section: Discussionmentioning

confidence: 99%

“…In the present case, spindle-shaped cells were arranged in a storiform pattern and numerous pleomorphic cells with high mitotic rates were observed. Immunohistochemical staining for vimentin and CD68 is usually positive 14 . Moreover immunohistochemical staining for calretinin, cytokeratin, TTF-1, CD56, LCA, CD34, and S-100 proteinare negative 14 .…”

Section: Discussionmentioning

confidence: 99%

“…Immunohistochemical staining for vimentin and CD68 is usually positive 14 . Moreover immunohistochemical staining for calretinin, cytokeratin, TTF-1, CD56, LCA, CD34, and S-100 proteinare negative 14 . However, there is no specific immunohistochemical stain that confirms the diagnosis 15 .…”

Section: Discussionmentioning

confidence: 99%

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Cutaneous Metastatic Undifferentiated Pleomorphic Sarcoma from a Mediastinal Sarcoma

2015

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Undifferentiated pleomorphic sarcoma, known as malignant fibrous histiocytoma, is a malignant neoplasm that arises in both soft tissue and bones. In 2002, the World Health Organization declassified malignant fibrous histocytoma as a formal diagnostic entity and renamed it 'undifferentiated pleomorphic sarcoma not otherwise specified.' It most commonly occurs in the lower extremities and rarely metastasizes cutaneously. We report a case of cutaneous metastatic undifferentiated pleomorphic sarcoma of the buttocks occurring in a 73-year-old man diagnosed with mediastinal sarcoma 4 years previously. He first noticed the mass approximately 2 months previously. Histological findings with immunomarkers led to a final diagnosis of cutaneous metastatic sarcoma from mediastinal undifferentiated pleomorphic sarcoma.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Cutaneous Metastatic Undifferentiated Pleomorphic Sarcoma from a Mediastinal Sarcoma

2015

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“…The most frequent site of UPS is the extremities, followed by the trunk and retroperitoneum, and only a few cases of UPS at other sites have been reported. [1][2][3][4][5][6][7][8] UPS originating in the abdomen is rare, and primary UPS in the porta hepatis is extremely rare. Cases of primary UPS in the liver and gallbladder have been reported in the English literature [1][2][3]5 but not cases of UPS in the porta hepatis.…”

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confidence: 99%

Undifferentiated Pleomorphic Sarcoma Originating in the Porta Hepatis: Report of a Rare Case

Okimoto

Kobayashi

Kuroda

et al. 2018

International Surgery

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Undifferentiated pleomorphic sarcoma (UPS) is a soft tissue sarcoma in adults. Although it can occur in any part of the body, its most common site is the extremities, followed by the trunk and retroperitoneum. Here, we describe a rare case of UPS originating in the porta hepatis of an 83-year-old man that was incidentally detected via contrast-enhanced computed tomography. Because malignancy was suspected, we performed a tumor resection with cholecystectomy. Consistent with a diagnosis of UPS, histopathology revealed highly cellular lesions with scattered pleomorphic spindle cell fascicles arranged in a storiform pattern; further, results of tests for all immunohistochemical markers were negative. One year after surgery, the patient is currently doing well without any evidence of tumor recurrence. To our knowledge, this is the first report of UPS originating in the porta hepatis.

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Endobronchial Malignant Fibrous Histiocytoma: Case Report of an Unusual Presentation and Palliative Flexible Bronchoscopic Resection

et al. 2012

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Primary malignant fibrous histiocytoma (MFH) of the lung is a very rare neoplasm that usually presents as a parenchymal mass. Here we report an unusual case of primary MFH of the bronchus, showing relatively benign clinical features. We performed a palliative resection via flexible bronchoscopy, using a polypectomy snare. The patient has survived for over 2 years after being diagnosed with an endobronchial mass, later found to be MFH, and 14 months post-debulking. There is a possibility that endobronchial MFH has a more favorable prognosis than MFH of other origins. If this is true, interventional bronchoscopy can be a reasonable option for non-operable cases of MFH.

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Primary Malignant Fibrous Histiocytoma of the Pleura

Cited by 3 publications

References 9 publications

Cutaneous Metastatic Undifferentiated Pleomorphic Sarcoma from a Mediastinal Sarcoma

Cutaneous Metastatic Undifferentiated Pleomorphic Sarcoma from a Mediastinal Sarcoma

Undifferentiated Pleomorphic Sarcoma Originating in the Porta Hepatis: Report of a Rare Case

Endobronchial Malignant Fibrous Histiocytoma: Case Report of an Unusual Presentation and Palliative Flexible Bronchoscopic Resection

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