Primary liposarcoma of the stomach

Bostanoğlu, Akın; Yildiz, Barış Doğu; Kulaçoğlu, Sezer; Avşar, Fatih Mehmet

doi:10.4318/tjg.2013.0510

Cited by 10 publications

(8 citation statements)

References 7 publications

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“…Liposarcoma, a kind of malignant tumor of mesenchymal origin, is one of the most common soft tissue sarcomas[ 1 ]. However, liposarcoma of the stomach is extremely rare.…”

Section: Discussionmentioning

confidence: 99%

“…There is a risk of local recurrence but a low potential for metastasis[ 5 ]. Dedifferentiated liposarcomas and well-differentiated liposarcomas are related[ 1 ]. Approximately 10% of dedifferentiated liposarcomas are recurrences of well-differentiated liposarcomas[ 3 ].…”

Section: Discussionmentioning

confidence: 99%

“…The type of symptom that appears depends on the location and size of the tumor and the presence of ulcerations[ 3 ]. Space-occupying lesions of the stomach or abdominal cavity contribute to the appearance of clinical symptoms[ 1 ]. When the submucosal mass extrudes into the lumen, it can cause traumatic and inflammatory changes and result in necrosis, ulceration, and hemorrhage[ 11 ].…”

Section: Discussionmentioning

confidence: 99%

“…Liposarcoma is one of the most common mesenchymal neoplasms[ 1 ], and liposarcomas are classified histologically into five subtypes[ 2 ]. However liposarcoma of the stomach is rare, and only 37 cases have been reported in the literature.…”

Section: Introductionmentioning

confidence: 99%

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Liposarcoma of the stomach: Report of two cases and review of the literature

Kang¹,

Xue²,

Wang³

et al. 2018

WJG

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Liposarcoma of the stomach is extremely rare, and only 37 cases have been reported worldwide. We herein report two cases of liposarcoma of the stomach. The first patient was referred to our hospital with upper abdominal discomfort. The endoscopic examination revealed a tumor mass about 3 cm in diameter. The patient underwent a partial gastrectomy and had an uneventful recovery. The histopathological examination revealed a well-differentiated liposarcoma. The second patient had symptoms of upper abdominal discomfort combined with nausea and anorexia. Several palpable masses were found with endoscopy. Endoscopic submucosal dissection was the treatment used, and the postoperative course was uneventful. The histopathological diagnosis was a well-differentiated liposarcoma. The two patients did not undergo any adjuvant therapy. They are both currently in good condition without recurrence. Therefore, we believe that the outcome of liposarcoma of the stomach is positive, and surgical resection may be the first choice for treatment at present.

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“…Liposarcoma, a kind of malignant tumor of mesenchymal origin, is one of the most common soft tissue sarcomas[ 1 ]. However, liposarcoma of the stomach is extremely rare.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Liposarcoma of the stomach: Report of two cases and review of the literature

Kang¹,

Xue²,

Wang³

et al. 2018

WJG

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“…In general, liposarcomas are extremely uncommon in the gastrointestinal tract (6)(7)(8)(9)(10)(11)(12)(13), especially at the gastroesophageal junction. we describe herein the first case of DDLPS of the gastroesophageal junction.…”

Section: Introductionmentioning

confidence: 99%

Dedifferentiated liposarcoma of the gastroesophageal junction

Askan¹,

Bağcı²,

Hameed³

et al. 2015

TJPATH

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Liposarcoma is one of the most common sarcomas in adults, but very rarely presents as a primary in the upper gastrointestinal system. Herein, we present a 71-year-old male patient who underwent wedge excision biopsy twice and then fine needle aspiration and total gastrectomy for a recurrent gastroeosophageal junction mass. In microscopic sections, both well-differentiated and dedifferentiated components were seen. Tumor cells were positive for MDM2, CDK4 and negative for CD117, DOG1, CD34, SMA, Desmin, S-100, HMB45, SOX10, AE1/AE3, CAM5.2, CK18. Fluorescence in situ hybridization (FISH) was performed and MDM2 gene (12q15) amplification was detected. According to these findings, a diagnosis of dedifferentiated liposarcoma was supported. We believe this is the first reported case of dedifferentiated liposarcoma of the gastroesophageal junction.

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