Primary Ewing''s Sarcoma of the Occipital Bone —Case Report—

Zenke, Kiichiro; Hatakeyama, Tetsuhiro; Hashimoto, Hisaki; Sakaki, Saburo; Manabe, Kouji

doi:10.2176/nmc.34.246

Cited by 21 publications

(16 citation statements)

References 12 publications

(2 reference statements)

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“…1,8,27) The location is frequently the frontal and parietal convexities, 19,27) and less often the squama and the mastoid process of the temporal bone, 5,6,11,30) the ethmoid bone, 12) the orbit, 1,26,31) the petrous bone, 6,8,17,22,27) and the occipital bone. 6,9,32) Central nervous system involvement by secondary deposits from primary extracranial Ewing's sarcoma occurs in 10% to 33% of cases. 4,6,19) Early diagnosis is extremely important to obtain long-term survival because metastasis to the lungs and/or to other bones may occur in the very early stages of tumor development.…”

Section: Discussionmentioning

confidence: 99%

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Primary Ewing's Sarcoma of the Occipital Bone. Case Report.

Erol

Özveren

Özercan

et al. 2001

Neurol. Med. Chir.(Tokyo)

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A 17-year-old female presented with a very rare case of primary Ewing's sarcoma of the skull involving the occipitotemporal region. Systemic examination found no evidence of metastasis. The tumor was surgically removed, and the patient underwent radiotherapy and chemotherapy. Fourteen months after surgery there has been no recurrence of the tumor. Cranial primary Ewing's tumor has a good prognosis after radical surgery and adjuvant therapy.

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Section: Discussionmentioning

confidence: 99%

“…Only 22 cases of primary cranial Ewing's sarcomas have been reported [1][2][3]5,[8][9][10][11][12]14,[16][17][18][19]21,22,[31][32][33] in addition to a series of 14 patients with primary cranial Ewing's sarcoma. 6) Ewing's sarcoma usually occurs in the long bones of the lower limbs, generally in patients less than 15 years of age.…”

Section: Introductionmentioning

confidence: 99%

Primary Ewing's Sarcoma of the Occipital Bone. Case Report.

Erol

Özveren

Özercan

et al. 2001

Neurol. Med. Chir.(Tokyo)

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“…Ewing [49] mentioned cranial lesions in his original report. Cases of EFT are reported in the calvarium [19,49 -54], the frontotemporal bone [37], the temporal bone [55][56][57][58][59][60], the zygoma [61], the temporal-parietal region [62,63], the occipital bone [6,64], the frontoorbital bone [4], the orbit [65], the orbit and paranasal sinuses [66], the ethmoid bone [67], the nasal cavity and nasopharynx [68 -71], the maxilla [18], the mandible [48,72], the skull base [62,73], the petrous bone [58,74], the mastoid [75,76], the sphenoid ridge [48], the clivus [77], and the floor of the middle cranial fossa [78].…”

Section: Skullmentioning

confidence: 99%

Ewing's Family of Tumors Involving Structures Related to the Central Nervous System: A Review

et al. 2000

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This review consolidates information gleaned from several case reports and larger series on Ewing's sarcoma family of tumors (EFT) involving structures related to and found in the central nervous system (CNS). These tumors involve the skull, the spinal column, adjacent soft tissues, the meninges, and the brain. We have separated the cases by skull region and spinal column level, and we discuss the attendant differences in prognosis following treatment by neurosurgery, radiation, and chemotherapy. Light and electron microscopic features can be used to differentiate EFT from other small round blue cell tumors that involve the CNS (central primitive neuroectodermal tumor, lymphoma, etc.). Recent molecular and genetic findings in EFT provide new diagnostic methods. We conclude that EFT involving the CNS and adjacent structures is not so rare as previously stated and that the prognosis is more favorable, as a rule, than for the more common examples arising in the long bones and pelvis.

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“…Radical surger y can , howeve r, play an im por tant role in achievin g local con tro l in cer tain areas (e.g. m and ible and skull), especially in tum or s < 5 cm in d iam eter w here the tr e at m e n t r e la te d m o r b id i ty w o u ld n o t b e increase d. 5,10,11 The local control rate in the present study was 71% .This ® gure is lower than the 90% ® gure reported in o th er ser ies. 12 T h ere a re tw o m ain facto r s affecting the local control rate, these are the initial tum or size an d the total rad iation dose delivered .…”

Section: Discussionmentioning

confidence: 99%

A Case of Primary Ewing Sarcoma of the Strap Muscle

Ahn¹,

Sohn²,

Jeong³

2017

Korean J Otorhinolaryngol-Head Neck Surg

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A bstractIntroduction and pur pose. Primary Ewing's sarcoma arising from the bones of the head and neck region is extremely rare representing only 1± 4% of all Ewing's sarcoma cases. Previous reports suggest a better prognosis for that particular anatomic site. The purpose of this study was to analyze the clinico-epidemiologic characteristics of that rare clinical presentation, as well as its patterns of failure and prognosis following treatment. M ater ials and methods. This study included a retrospective review of the medical records of patients with the diagnosis of Ewing's sarcoma of the head and neck region treated at King Faisal Specialist Hospital and Research Center between 1975 and Results . Out of a total number of 24 cases analyzed, there were 17 males and 7 fem ales with a ratio of 2.4:1. The m edian age at diagnosis was 16.5 years. A painful swelling was the m ost comm on clinical presentation. The m axilla was the m ost common site of presentation (9/24 cases). There were 3/24 cases who presented with metastatic disease at diagnosis. The m ajority of patients (16/24 cases) had a tum or size >10 cm . M ost patients were treated with systemic chem otherapy plus localized irradiation following an initial biopsy. W ith a m ean follow up of 3.4 years, the 5-year actuarial overall survival (OS) for the whole group was 53% , while the 5-year actuarial disease-free survival (DFS) was 30% . These ® gures were higher than those reported from our institution for young patients (£ 14 years treated for Ewing' s sarcom a in other anatom ic locations (30 % v 15% ). The response to chem otherapy was the only prognostic factor that affected both the OS and DFS. C onclusio n. The prognosis of Ewing's sarcoma of the head and neck region is slightly better than that of other anatomic sites. The response to systemic chem otherapy is one of the m ost important prognostic factors affecting both DFS and OS of Ewing's sarcoma of the head and neck. M ultimodality therapy consisting of an initial biopsy, aggressive combination chem otherapy and localized radiotherapy is the treatment of choice for Ewing's sarcoma of the head and neck region and m ay result in long-term survival.

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Primary Ewing''s Sarcoma of the Occipital Bone —Case Report—

Cited by 21 publications

References 12 publications

Primary Ewing's Sarcoma of the Occipital Bone. Case Report.

Primary Ewing's Sarcoma of the Occipital Bone. Case Report.

Ewing's Family of Tumors Involving Structures Related to the Central Nervous System: A Review

A Case of Primary Ewing Sarcoma of the Strap Muscle

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