Primary Ewing's Sarcoma of the Occipital Bone. Case Report.

Erol, Fatih Serhat; Özveren, Mehmet Faik; Özercan, İbrahim; Topsakal, Cahide; Akdemir, Ismail

doi:10.2176/nmc.41.206

Cited by 10 publications

(16 citation statements)

References 23 publications

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“…Rarely, EWS may diffusely affect the anterior skull base in carpeting fashion, clinically leading to multiple cranial nerve involvement. 1,2,4 In our series, we present primary calvarial EWS at different locations, including frontal and temporoparietal bones, anterior skull base, sphenoid bone, and at rarely described locations such as the posterior fossa. EWS is known for its rapid extradural spread, though there are isolated reports of intradural involvement.…”

Section: Discussionmentioning

confidence: 99%

Primary Calvarial Ewing Sarcoma: A Case Series

Mohindra

Tripathi

Batish

et al. 2021

J Neurol Surg B Skull Base

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Background Calvarial Ewing tumor is a relatively rare differential among bony neoplasms. We present our experience of managing primary calvarial Ewing sarcoma (EWS), highlighting their clinical and radiological findings. Method In a retrospective analysis, we evaluated our 12-year database for pathologically proven EWS. A literature search was conducted for the comparative presentation and update on the management and outcome. Result From January 2008 to December 2020, we managed eight patients (male:female = 5:3; age range 6 months to 19 years, mean 11.5 years) harboring primary calvarial EWS. All cases underwent wide local excision; two patients required intradural tumor resection, while one required rotation flap for scalp reconstruction. Mean hospital stay was 8 days. All patients received adjuvant chemo- and radiotherapy. Three patients remained asymptomatic at 5 years of follow-up, while two patients died. Conclusion Primary calvarial EWS is a rare entity. It usually affects patients in the first two decades of life. These tumors can be purely intracranial, causing raised intracranial pressure symptoms, which may exhibit rapidly enlarging subgaleal tumors with only cosmetic deformities or symptoms of both. Radical excision followed by adjuvant therapy may offer a favorable long-term outcome.

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Section: Discussionmentioning

confidence: 99%

Primary Calvarial Ewing Sarcoma: A Case Series

Mohindra

Tripathi

Batish

et al. 2021

J Neurol Surg B Skull Base

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“…Primary Ewing's sarcoma of the skull may be located not only in the calvarial bones, but also in the orbita and the orbital roof, the ethmoid, sphenoid, or petrous bones. [11][12][13][14][15][16] The most common symptom is local swelling enlarging during the course of a few weeks to a few months. 17 MRI of primary Ewing's sarcoma of the skull usually shows low intensity on T1-weighted images, mixed intensity on T2weighted images, and marked and inhomogeneous enhancement by gadolinium diethylenetriamine pentaacetic acid.…”

Section: Discussionmentioning

confidence: 99%

Entrapment of the Greater Occipital Nerve with Chronic Migraine and Severe Facial Pain: A Case Report

Son

2021

J Neurol Surg A Cent Eur Neurosurg

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Background and Objective Primary Ewing's sarcoma of the skull is a very rare malignant neoplasm, predominantly occurring in children and adolescents. We describe here the clinical, neuroradiologic, and histopathologic features of a patient with primary Ewing's sarcoma of the skull and discuss the standards of therapy for this type of tumor. Clinical Presentation This 18-year-old male patient presented with a primary Ewing's sarcoma of the skull, involving the dura of the frontal and parietal lobes of the left cerebral hemisphere. He was treated with gross total surgical excision of tumor, skull reconstruction, chemotherapy, and irradiation. Twelve years after the surgery, the patient has no evidence of local recurrence or distant metastases. Radical surgical excision of the primary tumor with safety margins is thought to play a role in the favorable clinical course. Conclusion The presented case is the longest surviving patient after treatment of primary Ewing's sarcoma of the skull bone. This rare type of tumor may allow better survival rates under adequate management than sarcoma elsewhere in the body.

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“…Sphenoid and ethmoid bones are less commonly involved. [2,3,4] Clinically tumour may mimic osteomyelitis because of pain, fever and leucocytosis. [5] Ill-defined destructive intramedullary lesions involving diaphysis of the long tubular bones are seen in ES.…”

Section: Discussionmentioning

confidence: 99%

Cytodiagnosis of Primary Ewing Sarcoma of the Skull: Diagnostic Clues and Difficulties

Saxena¹,

Nayak²

2021

Ann of Pathol and Lab Med

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Ewing sarcoma is a rare primary neoplasm of bone representing approximately 6-8% of all malignant bone tumours. Because of its aggressive clinical behaviour and rapid dissemination to other sites, an early accurate diagnosis is of utmost importance. It shares morphological features with other round cell tumors. Common differentials include lymphoblastic lymphoma, neuroblastoma, rhabdomyosarcoma and neuroendocrine tumours. Due to the morphological overlap, critical evaluation of the cellular details is essential. Fine needle aspiration cytology becomes a successful diagnostic tool when the subtle diagnostic clues and difficulties are considered during diagnosis. Judicious use of ancillary techniques will also aid in arriving at an accurate diagnosis. We present the case of a seven-year-old boy who presented with painful swelling of the scalp. Aspiration smears were cellular and showed atypical small round cells. Evaluation of morphological details along with special stains and immunohistochemistry in cell block preparation aided in rendering a diagnosis of Ewing sarcoma. The awareness of overlapping features in clinical presentation, morphology and immunohistochemical findings will help to arrive in the proper diagnosis. Early diagnosis on cytology samples can help in timely initiation of treatment, thus improve prognosis.

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Primary Ewing's Sarcoma of the Occipital Bone. Case Report.

Cited by 10 publications

References 23 publications

Primary Calvarial Ewing Sarcoma: A Case Series

Primary Calvarial Ewing Sarcoma: A Case Series

Entrapment of the Greater Occipital Nerve with Chronic Migraine and Severe Facial Pain: A Case Report

Cytodiagnosis of Primary Ewing Sarcoma of the Skull: Diagnostic Clues and Difficulties

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