Primary cutaneous carcinosarcoma: review and presentation of a case with emphasis on clinical characteristics and management

Extraordinarily aggressive cutaneous sarcomatoid squamous cell carcinoma of the face: a case report

“…Sarcomatoid (spindle cell) carcinomas are unusual variants of SCC, accounting for 3% of all squamous carcinomas in the head and neck region [ 10 ]. They predominantly arise in visceral organs (breast, lung, gastrointestinal tract, kidney, urinary bladder, thyroid, and others) and rarely occur as primary cutaneous tumors [ 11 ].…”

“…Therefore, the standard local treatment for cutaneous SSCC is complete excision of all the affected areas rather than wide excision of the primary lesion and each metastasis [ 4 ]. Surgical treatment with a 10 mm free circumferential margin, including deep excision to the fascia, is recommended [ 11 ].…”

“…There is no high-level evidence for the benefits of adjuvant chemo- or radiotherapeutic treatment on the sarcomatous part of the cutaneous SSCC [ 11 ]. However, there are arguments that chemotherapy [ 17 ] or radiotherapy [ 18 ] may be necessary [ 19 ].…”

“…Cutaneous SSCC is a very rare type of cancer with unknown causes, ambiguous clinical manifestation, and a poor prognosis, and its accompaniment with in-transit metastasis or satellites is even rarer [ 11 ]. In this case, it was not ideal that the intervals between the surgeries were long.…”

Primary cutaneous sarcomatoid carcinoma presenting as a rapidly‐growing and ulcerative tumor of the skin

“…Wide surgical excision is the treatment of choice for cutaneous SC. Excision with a 10-mm free circumferential margin including a deep excision to the fascia is recommended [5]. Adjuvant chemotherapy or radiotherapy has not been shown to be beneficial for treating the SC.…”