Extraordinarily aggressive cutaneous sarcomatoid squamous cell carcinoma of the face: a case report

Abstract

Sarcomatoid squamous cell carcinoma (SSCC), a biphasic malignant tumor consisting of atypical squamous epithelial and mesenchymal elements mixed with epithelioid and spindle cells, is a variant of squamous cell carcinoma. Cutaneous SSCC is very rare and aggressive and has a poor prognosis. Here, we report a case of cutaneous SSCC with satellites and in-transit metastases. A 79-year-old woman presented with a protruding mass on the left temporal area sized 1.2× 1.0 cm. The punch biopsy report indicated keratoacanthoma or well-differentiated squamous cell carcinoma. The size of the tumor increased to 2.7× 2.0 cm after 8 days. An excisional biopsy was performed with a 2 mm safety margin. The tumor was identified as SSCC with a clear resection margin. Reoperation was performed thrice with an increased safety margin of 10 mm; however, the cancer recurred along with satellites and in-transit metastases. Chemoradiotherapy was administered; however, the size of the tumor increased along with satellites and in-transit metastases. The patient expired 162 days after the initial excision. Complete excision and immediate multidisciplinary approach should be combined during the early stages due to the aggressiveness and poor prognosis of cutaneous SSCC with satellites and in-transit metastasis.

Simultaneous diagnosis and resection of orofacial rhabdomyosarcoma with frozen section biopsy: a case report

“…Once rhabdomyosarcoma is highly suspected, although biopsy for confirmation of histology is required when complete surgical excision is not available, primary surgical resection with reconstruction should be executed if the site and size of the tumor permit removal of the entire gross tumor without anatomical or functional defects [ 7 - 9 ]. Additionally, all rhabdomyosarcoma patients need chemotherapy with a backbone of vincristine, dactinomycin and cyclophosphamide, and radiotherapy is applied in almost all patients to enhance the outcome [ 1 ].…”

Malignant melanoma associated with a plaque-type blue nevus of the cheek: a case report

“…Wide excision with supraomohyoid neck dissection and superficial parotidectomy were performed. The invasion depth was 11 mm and the safety margin was set to 2 cm [ 3 , 4 ]. The lymph node biopsies were negative for metastasis.…”