Primary angiosarcoma of breast: A case report

Bhosale, Suresh; Kshirsagar, Ashok Y; Patil, Mandar Vilas; Wader, Jyotsna; Nangare, Nitin; Patil, Pranita P.

doi:10.1016/j.ijscr.2013.01.016

Cited by 24 publications

(43 citation statements)

References 15 publications

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“…Some patients are diagnosed during pregnancy or shortly after delivery (7); it is believed that there is a hormonal effect on the development of this disease. However, there are several cases of bilateral tumors diagnosed in postmenopausal period (8).…”

Section: Discussionmentioning

confidence: 99%

“…Rarely, the tumor may show a soap bubble appearance. They rarely manifest coarse, nonbranching microcalcifications (8). PBA could be seen as having focal asymmetry, an oval or lobular mass feature, and rarely there may be skin thickening (1).…”

Section: Discussionmentioning

confidence: 99%

“…Sonography usually shows a solid mass that may have well-defined or lobulated margins and with either hypoechoic or hyperechoic appearance. There is often no posterior shadowing (8). PBA can be seen as a complex mass with both cystic and solid regions (10) which can show adjacent tubular structures consistent with vessels (9).…”

Section: Discussionmentioning

confidence: 99%

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Primary Angiosarcoma of the Breast: MRI Findings

Lee

Seo

Whang

2018

Investig Magn Reson Imaging

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Primary Angiosarcoma of the Breast: MRI Findings

Lee

Seo

Whang

2018

Investig Magn Reson Imaging

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“…Há poucos relatos na literatura a respeito dos achados de imagem do angiossarcoma de mama na RM 7,11 . A apresentação mais comum é de um nódulo heterogêneo com baixa intensidade de sinal nas imagens ponderadas em T1 e alta intensidade de sinal nas imagens ponderadas em T2, com áreas de ausência de sinal em razão de vasos no interior da lesão 5,7,9,11,12 . A presença de cinética do tipo washout e de áreas de hemorragia favorecem tumores de alto grau 6,13 .…”

Section: Relato Do Casounclassified

Angiossarcoma primário de mama: desafio diagnóstico

Freire¹,

Barra²,

Camelo³

et al. 2017

Rev. Bras. Mastol. (Impr.)

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RESUMOOs autores expõem um caso de uma mulher de 57 anos que apresentou uma massa palpável na mama direita. Na mamografia, foi identificada uma assimetria focal com gordura de permeio, sem achado suspeito à ultrassonografia. A ressonância magnética das mamas, com meio de contraste, demonstrou um nódulo irregular e mal definido, com baixo sinal em T1 sem supressão de gordura e alto sinal em T2 com supressão de gordura. Apresentou também realce heterogêneo irregular com septos espessos realçantes medindo 5,3 cm, cinética inicial rápida e curva do tipo persistente. Uma nova ultrassonografia dirigida foi realizada, sendo observado um nódulo hipoecoico de 1,2 cm, associado à alteração da ecogenicidade do parênquima mamário adjacente. Realizou-se biópsia a vácuo do nódulo hipoecoico e do parênquima adjacente, guiada por ultrassom. O estudo histopatológico demonstrou angiossarcoma primário da mama de baixo grau. O PET-CT, realizado 6 meses após a cirurgia, não evidenciou recidiva ou metástases. ABSTRACT

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“…In addition, the role of adjuvant chemotherapy and/or RT has also been elucidated, which suggested that patients with high risk of recurrence might benefit from adjuvant therapy. 10 , 11…”

Section: Introductionmentioning

confidence: 99%

Management experiences of primary angiosarcoma of breast: a retrospective study from single institute in the People’s Republic of China

Hu¹,

Xin²,

Yan³

et al. 2015

OTT

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BackgroundPrimary angiosarcoma of breast (PAOB) is a rare and highly aggressive malignancy. There is no general agreement on optimal treatments or prognostic factors for this orphan disease. The objective of this study was to investigate the clinicopathologic features and management experiences of PAOB.MethodsWe performed a retrospective review of medical and pathologic records of 17 consecutive patients diagnosed with PAOB between January 2000 and February 2014 at FuDan University Shanghai Cancer Center. We evaluated the clinical characteristics, multimodality treatments, and associated clinical outcomes.ResultsA total of 16 patients were included in this retrospective study (median age at PAOB presentation 33.5 years, range: 19–56 years). Palpable tumor with or without breast skin ecchymosis presented as the most common initial symptom. All patients underwent surgery with curative intent. Median disease-free survival and overall survival (OS) were 9 months and 13.6 months, respectively. One-year and 3-year disease-free survival rates were 43.8% and 6.3%, with OS rates of 93.8% and 78.1%, respectively. High histologic grade indicated poorer OS by univariate analysis (P=0.01). However, neither adjuvant chemotherapy nor radiotherapy contributed to clinical outcomes in our series.ConclusionPAOB is considered as an infrequent breast neoplasm with aggressive characteristics. Histologic grade and early metastasis (within 12 months after diagnosis) are associated with poor prognosis. Regardless of grade, additional benefit was not observed with adjuvant therapy.

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Primary angiosarcoma of breast: A case report

Abstract: Primary angiosarcoma of the breast is a rare malignancy with a poor prognosis, even after complete resection. Surgery is the mainstay of treatment with a limited role for chemotherapy and radiotherapy.

Cited by 24 publications

References 15 publications

Primary Angiosarcoma of the Breast: MRI Findings

Primary Angiosarcoma of the Breast: MRI Findings

Angiossarcoma primário de mama: desafio diagnóstico

Management experiences of primary angiosarcoma of breast: a retrospective study from single institute in the People’s Republic of China

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Primary angiosarcoma of breast: A case report

Abstract: Primary angiosarcoma of the breast is a rare malignancy with a poor prognosis, even after complete resection. Surgery is the mainstay of treatment with a limited role for chemotherapy and radiotherapy.

Cited by 24 publications

References 15 publications

Primary Angiosarcoma of the Breast: MRI Findings

Primary Angiosarcoma of the Breast: MRI Findings

Angiossarcoma primário de mama: desafio diagnóstico

Management experiences of primary angiosarcoma of breast: a retrospective study from single institute in the People&rsquo;s Republic of China

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Management experiences of primary angiosarcoma of breast: a retrospective study from single institute in the People’s Republic of China