Prevention of CCl4-induced nephrotoxicity with Sonchus asper in rat

Ameliorative Effects of Pomegranate Peel Extract on Hepatotoxicity Induced by Carbon Tetrachloride in Mice

“…The hepatotoxic effect of CCl4 detected in the present study might be due to oxidative stress of CCl4 which induces reactive oxygen species (ROS) and depletes antioxidant defenses, including antioxidant enzymes and their substrates causing oxidative stress in multiple tissues [32]. The same authors reported that the mechanism of CCl 4 injury involves oxidative damage by metabolism of CCl 4 to trichloromethyl radical (CCl 3 ) which is subsequently changed into more destructive trichloromethyl peroxy radical (CCl 3 OO) in hepatocytes.…”

Alteration of renal function by potassium bromate (KBrO3): Protective effects of Launaea procumbens

“…L. procumbens is generally classified as Kingdom (Plantae), Order (Asterales), Family (Asteraceae), Tribe (Cichorieae), Genus (Launaea), and Species (procumbens). Chemical characterization showed that L. procumbens are composed of salicylic acid, vanllic acid, synergic acid, 2-methyl-resercinol, gallic acid and used against plant pathogenic fungi, nematocides and as allelopathic for inhibition of plant growth (Shaukat et al, 2003;Khan et al, 2010aKhan et al, , 2010b. Present study is designed to check the protective effect of L. procumben on urine function of kidney damaged …”

Ameliorative Effect of the Flavonoid Rich Fraction of Monodora myristica (Gaertn) Dunel Seed Extract against Carbon Tetrachloride-Induced Hepatotoxicity and Oxidative Stress in Rats

“…Environmental sources of oxidative stress include xenobiotics, organic solvents, pesticides, tobacco smoke, anaesthetics, drugs and radiation [5]. Crude extracts of some medicinal plants, their fractions and bioactive compounds are known to play essential role in detoxification of such toxins and mop up free radicals [6,7].…”