Prevalence of multiple micronutrient deficiencies amongst pregnant women in a rural area of Haryana

Pathak, Praveen; Kapil, Umesh; Kapoor, Sorabh; Saxena, Renu; Kumar, Anand; Gupta, Nidhi; Dwivedi, Sada Nand; Singh, Rajvir; Singh, Preeti

doi:10.1007/bf02828117

Cited by 127 publications

(106 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In this study, unlike zinc, no pregnant women were found deficient in serum copper levels. In line with our observation, a very low prevalence (2.7 %) of copper deficiency was reported from pregnant women in India [16] and in China [35].…”

Section: Discussionsupporting

confidence: 90%

“…Zinc is required for cellular division and differentiation, and is an essential nutrient for normal embryogenesis. Zinc is a cofactor for the synthesis of a number of enzymes, DNA, and RNA [16]. Zinc deficiency has been associated with complications of pregnancy and delivery, as well as with growth retardation and congenital abnormalities in the fetus [4].…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence of iron deficiency in pregnant women in the studies conducted in UK [32]; in China [33]; and in India [16] was 34, 42.6 and 73.4 % respectively. The high prevalent of iron deficiency amongst pregnant women found in the present study was possibly due to the inadequate iron consumption or the bread eaten by Iranian is made from flour of high extraction and without added leaven.…”

Section: Discussionmentioning

confidence: 99%

“…However, this prevalence of magnesium deficiency is \43.6 % showed in a study in India [16], and 51.5 % in China [35]. Low serum magnesium status during pregnancy could be due to an active transport of the element across the placenta into the fetus estrogen domination to which these women are exposed [40].…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Serum Level of Some Minerals during Three Trimesters of Pregnancy in Iranian Women and Their Newborns: A Longitudinal Study

Tabrizi

Pakdel

2013

Ind J Clin Biochem

View full text Add to dashboard Cite

Concentrations of various trace elements are altered during pregnancy with changes in the mother's physiology and the requirements of growing fetus. The aim of the present longitudinal study was to learn the changes of micronutrients Iron (Fe), Calcium (Ca), zinc (Zn) Magnesium (Mg) and copper (Cu) of pregnant woman and their relations with newborns levels. Serum levels of iron, calcium, zinc, magnesium and copper of 162 pregnant women and their newborns were determined by an inductively couple plasma mass spectrometer (ICP/MS). The results showed that majority (41 %) of pregnant women were in age group 26-36 years 55 % had high school and diploma levels of education and the total income ranged between 3 and 5 Rials million per month There was significant difference in iron levels during first, second and third trimesters, 76.0 ± 17.8, 63.5 ± 15.2 and 70.1 ± 14.4 lg/dl respectively. Significant difference was shown in zinc levels 79.5 ± 15, 74.5 ± 16.1, and 65.3 ± 14.9 lg/dl during three trimesters. Copper levels during pregnancy were significantly different (130.9 ± 43.5, 172.0 ± 38.94, 193.2 ± 28.5 lg/dl. The serum levels of calcium and magnesium during pregnancy were constant (Ca: 8.96 ± 0.48, 8.86 ± 0.47, 8.91 ± 0.42 mg/dl and Mg: 2.10 ± 0.21, 2.08 ± 0.28, 2.09 ± 0.29 mg/dl). Results showed that 13 % of pregnant women had hypocalcaemia and hypomagnesaemia. Thirty eight percent and 42 % of pregnant women had iron and zinc deficiency respectively. In this study, unlike zinc, no pregnant women were found deficient in serum copper levels. Calcium, iron, zinc, copper and magnesium levels in the newborn's cord blood were 8.93 ± 0.43, 106.0 ± 26.1, 85.35 ± 16.6, 57.04 ± 13.8 and 1.99 ± 0.27 mg/dl respectively. In the present study the levels of iron and zinc in cord blood were higher than the levels of iron and zinc in maternal serum. The mean level of copper in cord blood serum in the current study was lower than maternal values. The mean serum calcium and magnesium in the serum cord blood and in the serum of the pregnant women were similar.

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Serum Level of Some Minerals during Three Trimesters of Pregnancy in Iranian Women and Their Newborns: A Longitudinal Study

Tabrizi

Pakdel

2013

Ind J Clin Biochem

View full text Add to dashboard Cite

show abstract

“…Evidence for synergistic effects of these micronutrients on Fe and folic acid supplementation for the treatment of anaemia is inconsistent (15)(16)(17)(18)(19) , although it is known that Cu has a role in haematopoiesis (20) and vitamin A and b-carotene have been shown to improve Fe absorption, possibly by preventing the inhibitory effects of phytates and polyphenols (21,22) . Regardless of these possible synergies, it is indisputable that girls approaching childbearing age would benefit from the correction of other prevalent nutritional deficiencies, particularly of vitamin A (23)(24)(25)(26)(27) and Ca (28) .…”

Section: Discussionmentioning

confidence: 99%

Leaf concentrate as an alternative to iron and folic acid supplements for anaemic adolescent girls: a randomised controlled trial in India

Vyas

Collin

Bertin

et al. 2009

Public Health Nutr.

View full text Add to dashboard Cite

Objective: Despite public health campaigns based on Fe and folic acid supplements, Fe-deficiency anaemia remains highly prevalent among women in India. We investigated leaf concentrate as an alternative to Fe and folic acid supplements for treating anaemia in adolescent girls. Design: Randomised controlled two-arm trial over 3 months: one group received daily Fe and folic acid (IFA; 60 mg Fe, 500 mg folic acid); the other daily leaf concentrate (LC; 5 mg Fe, 13 mg folic acid). Hb concentration, mean cell volume, serum Fe, serum ferritin and total Fe-binding capacity were measured pre-and post-intervention. Setting: Jaipur, India. Subjects: One hundred and two adolescent girls aged 14-18 years. Results: Of the 102 girls randomized to the two arms of the trial, four (3?9 %) were severely anaemic (Hb , 7 g/dl), twenty-eight (27?5 %) were moderately anaemic (Hb $ 7 g/dl, ,10 g/dl) and seventy (68?6 %) were mildly anaemic (Hb $ 10 g/dl, ,12 g/dl). In the IFA group, eleven girls (20?4 %) withdrew due to side-effects, compared with one girl (2?1 %) in the LC group (P 5 0?005). Total losses to followup were 14/54 in the IFA group and 2/48 in the LC group. At the end of the trial, none of the eighty-six remaining girls were severely anaemic, nine (10?5 %) were moderately anaemic and twenty-six (30?2 %) were mildly anaemic; fifty-one (59?3 %) had normal Hb levels ($12 g/dl). After adjustment for baseline values, LC was as effective as IFA in improving serum Fe parameters and treating anaemia. Conclusions: Leaf concentrate is an effective, and more palatable, alternative to Fe and folic acid supplements for treating anaemia in adolescent girls.

show abstract

Effect of Maternal Multiple Micronutrient vs Iron–Folic Acid Supplementation on Infant Mortality and Adverse Birth Outcomes in Rural Bangladesh

West

Shamim²,

Mehra

et al. 2014

JAMA

124

173

View full text Add to dashboard Cite

show abstract

Prevalence of multiple micronutrient deficiencies amongst pregnant women in a rural area of Haryana

Cited by 127 publications

References 35 publications

Serum Level of Some Minerals during Three Trimesters of Pregnancy in Iranian Women and Their Newborns: A Longitudinal Study

Serum Level of Some Minerals during Three Trimesters of Pregnancy in Iranian Women and Their Newborns: A Longitudinal Study

Leaf concentrate as an alternative to iron and folic acid supplements for anaemic adolescent girls: a randomised controlled trial in India

Effect of Maternal Multiple Micronutrient vs Iron–Folic Acid Supplementation on Infant Mortality and Adverse Birth Outcomes in Rural Bangladesh

Contact Info

Product

Resources

About