Prevalence of metabolic syndrome and its components among patients with various psychiatric diagnoses and treatments: A cross-sectional study

Alosaimi, Fahad D.; Abalhassan, Mohammed; Alhaddad, Bandar; Alzain, Nasser; Fallata, Ebtihaj O.; Alhabbad, Abdulhadi; Alassiry, Mohammed Z.

doi:10.1016/j.genhosppsych.2016.12.007

Cited by 24 publications

(22 citation statements)

References 36 publications

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“…A recent cross-sectional comparative study on the prevalence of MetS in patients maintained on AP in Qatar showed a higher level of BMI but similar measures of BP, fasting glucose, TG, and HDL (Hammoudeh et al 2018) when compared to our retrospective study. A Saudi study conducted on psychiatric patients also reported higher BMI (28.6 ± 7.7 kg/m 2 ), and fasting blood glucose (6.16 ± 2.48 mmol/L) when compared to ours (Alosaimi et al 2017). There are no other studies from the countries of the Arabic Peninsula (usually have similar ethnicity distribution) that compared the effects of various AP on the metabolic measures.…”

Section: Discussionsupporting

confidence: 42%

“…A study on patients with various psychiatric disorders from Saudi Arabia showed that the prevalence of the metabolic measures was not different when compared to those not taking AP. However, the intake of SGA was mainly associated with elevated BP (Alosaimi et al 2017). This variability in the changes of metabolic risk factors among the various studies could be attributed to several factors: genetics, ethnicity, age, gender, type of mental illness, type and dose of AP, duration of treatment, concomitant medications, family history of metabolic disorder, smoking, lifestyle, eating habits, etc.…”

Section: Discussionmentioning

confidence: 97%

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Risk Factors of Metabolic Syndrome Among Patients Receiving Antipsychotics: A Retrospective Study

Hammoudeh

Lawati

Ghuloum

et al. 2019

Community Ment Health J

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This study aimed to assess the differential effects of first-generation (FGA) and second-generation antipsychotics (SGA) on the prevalence of risk factors for metabolic syndrome among mentally ill patients in Qatar. We also wanted to check if there is proper adherence with the guidelines for prescribing antipsychotics and the monitoring of metabolic effects in this population. We collected the available retrospective data (socio-demographic, psychiatric, anthropometric, and metabolic measures) from the records of 439 patients maintained on antipsychotics. The majority were males, married, employed, having a psychotic disorder, and receiving SGA. Patients on SGA showed more obesity, higher BP, and more elevated triglycerides compared to those on FGA. The prevalence of the abnormal metabolic measures was high in this sample, but those on SGA showed a significantly higher prevalence of abnormal body mass index and BP. Obesity and hypertension were common in patients maintained on antipsychotics, especially those on SGA. Polypharmacy was common, and many metabolic measures were not monitored properly in those maintained on antipsychotics. More prospective studies with guided monitoring of the patients' clinical status and metabolic changes are needed to serve better this population of patients.

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Section: Discussionsupporting

confidence: 42%

Section: Discussionmentioning

confidence: 97%

Risk Factors of Metabolic Syndrome Among Patients Receiving Antipsychotics: A Retrospective Study

Hammoudeh

Lawati

Ghuloum

et al. 2019

Community Ment Health J

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“…By contrast, our results are consistent with to those of Alosaimi et al . () who surveyed 992 patients with serious mental illness (41.2%) in Saudi Arabia, but lower than that reported by John et al . () in 203 patients with serious mental illness (54.0%) in Australia, by Kumar et al .…”

Section: Discussionmentioning

confidence: 62%

Gender differences in metabolic syndrome risk factors among patients with serious mental illness

Tzeng

Chiang

Feng

et al. 2019

Int J Mental Health Nurs

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The prevalence of metabolic syndrome and its components continue to increase among patients with serious mental illness. This cross‐sectional study investigated whether metabolic syndrome prevalence and risk factors differ between male and female patients with serious mental illness. In total, 260 eligible patients were recruited from two hospitals. The data on demographic characteristics, lifestyle behaviour factors, biochemistry, and anthropometry were collected. Analyses were performed using multivariate logistic regression. Metabolic syndrome prevalence was 40.8% (35.1% in men and 46.8% in women). Among patients aged 40–49 years, metabolic syndrome prevalence was higher in men; however, the trend was reversed among patients aged 50 years or older. Notably, gender‐specific metabolic syndrome risk factors were observed. In men, they included low education level, high body mass index (BMI), prolonged illness, comorbid physical illness, and diagnosis of bipolar disorder, whereas they included being married, old age, and high BMI in women. Our findings suggest that mental health professionals should consider the gender‐ and age‐based metabolic syndrome prevalence trend in patients with serious mental illness when designing interventions for the study population to minimize metabolic syndrome prevalence.

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“…17 A multicentric research in the Kingdom of Saudi Arabia including 992 cases with various psychiatric illnesses concluded a 41.2% prevalence of metabolic syndrome, according to the IDF diagnostic criteria. 18 Prevalence of specific metabolic abnormalities was evaluated in the Saudi sample, including central obesity (42.2%), raised blood pressure (42.5%), raised fasting blood glucose (47.8%), and low HDL cholesterol levels (52.5%). 18 A Palestinian study focused on 250 cases with schizophrenia and determined a 43.6% prevalence rate of metabolic syndrome.…”

Section: Discussionmentioning

confidence: 99%

“…18 Prevalence of specific metabolic abnormalities was evaluated in the Saudi sample, including central obesity (42.2%), raised blood pressure (42.5%), raised fasting blood glucose (47.8%), and low HDL cholesterol levels (52.5%). 18 A Palestinian study focused on 250 cases with schizophrenia and determined a 43.6% prevalence rate of metabolic syndrome. 19 It is therefore evident that there is a notable variation in the research methodology such as sample size and sampling techniques, as well as the difference in the diagnostic criteria used among published research; the finding from the current research consistently shows higher rates in comparison with the international and regional literature.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Metabolic Syndrome among Bahraini Patients with Schizophrenia

Jahrami¹,

Ali²

2018

J Bah Med Soc

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Background and objectives: Metabolic syndrome comprise of a few cardiovascular risk factors that increase morbidity and mortality. To evaluate the prevalence of metabolic syndrome among Bahraini schizophrenia patients. Methods: Using a case-control design, 50 patients with schizophrenia (cases) were compared to 50 age-and sex-matched healthy controls for the prevalence of metabolic syndrome. The workout included: anthropometric measurements, such as weight, height, and waist and hip circumferences, fasting blood glucose, lipid profile, blood pressure, and past medical history. Descriptive statistics such as mean and standard deviations for continuous variables and frequency counts and proportions for categorical variables were used to summarize the demographic characteristics and the different variables of the metabolic syndrome. Odds ratio (OR) was computed to measure the levels of association between exposure (schizophrenia) and outcomes (metabolic syndrome). Results: Based on the International Diabetes Federation criteria, 48% cases had metabolic syndrome in comparison to 34% controls. A statistical difference was observed among the cases and controls with respect to three metabolic abnormalities i.e., central obesity (OR, 4.5; 95% confidence interval (CI), 1.6-13.1), raised triglyceride level (OR, 2.5; 95% CI, 0.9-7.3), and reduced level of high-density lipoprotein cholesterol (OR, 0.4; 95% CI, 0.2-1.1). Conclusion: The prevalence of metabolic syndrome is extremely high among the Bahraini patients with schizophrenia. Clinicians are encouraged to monitor the physical health and physical components in patients with schizophrenia to detect metabolic syndrome and reverse it. Further, studies need to merit racial variability in metabolic syndrome among patients with schizophrenia due to the difference in the predisposing factors.

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Prevalence of metabolic syndrome and its components among patients with various psychiatric diagnoses and treatments: A cross-sectional study

Abstract: The prevalence of MetS and its components among patients with psychiatric disorders is alarming irrespective of their diagnoses. Thus, metabolic screening especially among high risk groups is critical.

Cited by 24 publications

References 36 publications

Risk Factors of Metabolic Syndrome Among Patients Receiving Antipsychotics: A Retrospective Study

Risk Factors of Metabolic Syndrome Among Patients Receiving Antipsychotics: A Retrospective Study

Gender differences in metabolic syndrome risk factors among patients with serious mental illness

Prevalence of Metabolic Syndrome among Bahraini Patients with Schizophrenia

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