Prevalence of genital Chlamydia trachomatis infection in the general population: a meta-analysis

Huai, Pengcheng; Li, Furong; Chu, Tongsheng; Liu, Dianchang; Liu, Jian; Zhang, Furen

doi:10.1186/s12879-020-05307-w

Cited by 49 publications

(33 citation statements)

References 48 publications

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“…It is well described that Chlamydia trachomatis is one of the most relevant pathogens impacting global health. Here, the data demonstrated a similar prevalence shown in Latin America [22]. This fact reveals the importance of epidemiological surveillance at the regional level.…”

Section: Discussionsupporting

confidence: 86%

Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women

Hernández‐Rosas

Rey-Barrera²,

Conejo-Saucedo³

et al. 2021

Pathogens

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Background. Globally, Sexually Transmitted Infections (STIs) are a major cause of morbidity in sexually active individuals, having complications in reproduction health and quality of life. In concordance with the Sustainable Development Goals (SDG), the study aimed to investigate the prevalence of Candida spp., Ureaplasma spp., Trichomonas vaginalis, Neisseria gonorrhoeae, Chlamydia trachomatis, HSV, and Mycoplasma spp. from cervicovaginal samples and to correlate them with the gynecological history of the patients. Methods. Our analytical, prospective, and cross-sectional study included 377 women who participated in a reproductive health campaign during 2015–2016. Anthropometric and gynecological variables were obtained. Cervicovaginal specimens were collected and analyzed with a multiplex in-house PCR to detect Candida spp., Ureaplasma spp., Trichomonas vaginalis, Neisseria gonorrhoeae, HSV, Mycoplasma spp., and Chlamydia trachomatis. Results. The positive cases were 175/377 (46.4%) to at least one of the microorganisms. The most frequent pathogen detected in this population was Ureaplasma spp. (n = 111, 29.4%), followed by Mycoplasma spp. (n = 56, 14.9%) and Candida spp. (n = 47, 12.5%); 33.7% of the positive cases were single infections, whereas 12.7% had coinfection. The multiplex PCR assay was designed targeting nucleotide sequences. Conclusions. Our data demonstrated that monitoring STIs among asymptomatic patients will encourage target programs to be more precisely and effectively implemented, as well as make these programs more affordable, to benefit society by decreasing the prevalence of STIs.

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Section: Discussionsupporting

confidence: 86%

Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women

Hernández‐Rosas

Rey-Barrera²,

Conejo-Saucedo³

et al. 2021

Pathogens

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“…However, many industrialised countries including Australia, Canada, France, Malta, UK, and USA follow the CDC guidelines of opportunistically screening for chlamydia in sexually active women or both genders in the high-risk age group, or encouraging extensive testing such as Sweden. The worldwide prevalence of chlamydia at population level has been estimated at 2.9% (95% CI: 2.4–3.5) and specifically for Europe at 2.7% (95% CI: 1.9–3.6) [ 34 ]. In high-income countries such as Europe, chlamydia infections are most prevalent among young heterosexual adults with estimates of 3.6% (95% CI: 2.4–4.8) in women and 3.4% (95% CI: 1.9–5.2) in men aged 26 years or less at population level, and among MSM attending sexual health clinics [ 8 , 29 ].…”

Section: Discussionmentioning

confidence: 99%

Who Is Best to Test? A Systematic Review of Chlamydia Infections in Switzerland

Haag

Zemp

Hersberger

et al. 2020

IJERPH

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In many countries, community pharmacies provide sexual-health-related services to limit the spread of sexually transmitted infections (STIs), including chlamydia testing. To identify suitable target groups for pharmacy-based chlamydia testing in Switzerland, we aimed to assess chlamydia prevalence, identify risk groups, and delineate screening strategies. We conducted a systematic literature search up to December 2019 in PubMed, EMBASE, and Web of Science, according to the PRISMA guidelines, using as keywords “chlamydia”, “screening”, and “Switzerland”. Two researchers screened the title, abstract, and full-text article and assessed the methodological quality. The literature search generated 108 hits, and nine studies were included. Chlamydia prevalence ranged between 0.8 and 12.8%. Most frequently affected were undocumented women undergoing voluntary termination of pregnancy (12.8%, 95% CI: 8.4–18.9), HIV-positive men who have sex with men (10.9%, 95% CI: 9.2–17.6), and adult offenders (6.5%, 95% CI: 3.2–9.0). Systematic screening was suggested for the first two risk groups and women suffering a miscarriage. To conclude, chlamydia infections are prevalent in Switzerland, but the identified risk groups are difficult to reach for a pharmacy-based testing service. More studies are needed to identify suitable target groups, including customers seeking sexual health services, particularly emergency contraception users who already receive counselling for STIs at community pharmacies.

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“…Серед жінок вона була розповсюджена більше -3,1%, серед чоловіків -2,6%. Територіально найчастіше ця інфекція зустрічалася на американському континенті (4,5%), особливо в Латинській Америці (6,7%) [32].…”

Section: хламідійна інфекція сучасні дані про патогенезunclassified

Epidemiological and clinical trends of sexually transmitted infections. Literature review

Тутченко¹,

Бурка

Boyarchuk

et al. 2021

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This article presents modern data on epidemiological trends, pathogenesis, and mechanisms of persistence and acquisition of antibiotic resistance of the most common sexually transmitted infections (STIs): chlamydial infection, gonorrhea, trichomoniasis. Data on the frequency of chlamydial infection, gonorrhea, trichomoniasis detection in the DILA medical laboratory in the period from 2018–2020 are also presented.Analysis of epidemiological and microbiological studies indicates a significant increase in the STIs incidence in countries with high economic development and the need for constant revision of diagnostic and treatment approaches, based on new data on the pathogens physiology, mechanisms and levels of antibiotic resistance, possibilities of laboratory diagnostics. Analysis of the DILA data on the chlamydial infection, gonorrhea, trichomoniasis detection is coinciding with the world trends in the increase of their prevalence. At the same time, the analysis of the DILA data demonstrated an interesting clinical phenomenon as a presence of 2 STIs peaks in women: the first at 21–25 years and the second at 51–55 years old.Clinical manifestations of STIs are increasingly losing their typical features today. This indicates the need for a laboratory search for all common STIs in the region. Knowledge of the etiological factor of the inflammatory process allows choosing the correct antibiotic therapy and preventing the further development of antibiotic resistance. This article presents data on the various methods of STIs laboratory tests. Regular visits of women for cervical cancer screening are a good opportunity to screen for STIs. The ability to detect STIs in biomaterial in liquid cytology makes this option more accessible.Thus, since vaccines against common bacterial and protozoa STIs pathogens have not yet been developed, the promotion of hygiene of sexual behavior and timely detection of infected persons during examination or screening with subsequent etiopathogenetic treatment are the basis of the STIs control systems and their consequences prevention.

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Prevalence of genital Chlamydia trachomatis infection in the general population: a meta-analysis

Cited by 49 publications

References 48 publications

Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women

Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women

Who Is Best to Test? A Systematic Review of Chlamydia Infections in Switzerland

Epidemiological and clinical trends of sexually transmitted infections. Literature review

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