2017
DOI: 10.1148/radiol.2017161228
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Prevalence of Fatty Liver Disease and Hepatic Iron Overload in a Northeastern German Population by Using Quantitative MR Imaging

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Cited by 98 publications
(111 citation statements)
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References 45 publications
(52 reference statements)
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“…However, the sample size was calculated based on a power analysis to detect clinically valid correlation, which was successfully established in our study. Second, although we recruited patients clinically diagnosed with NAFLD, ~25% (five patients) of these participants showed PDFF generally regarded as none to minimally steatotic (≤5%) . However, with the given purpose to evaluate linearity, bias, and precision of QIB, it is beneficial to include the entire range of measurement.…”
Section: Discussionmentioning
confidence: 99%
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“…However, the sample size was calculated based on a power analysis to detect clinically valid correlation, which was successfully established in our study. Second, although we recruited patients clinically diagnosed with NAFLD, ~25% (five patients) of these participants showed PDFF generally regarded as none to minimally steatotic (≤5%) . However, with the given purpose to evaluate linearity, bias, and precision of QIB, it is beneficial to include the entire range of measurement.…”
Section: Discussionmentioning
confidence: 99%
“…Second, although we recruited patients clinically diagnosed with NAFLD,~25% (five patients) of these participants showed PDFF generally regarded as none to minimally steatotic (≤5%). 8,39 However, with the given purpose to evaluate linearity, bias, and precision of QIB, it is beneficial to include the entire range of measurement. We were also able to elaborate on a higher CV among patients with a lower range of PDFF.…”
Section: Discussionmentioning
confidence: 99%
“…There have been some studies focused on simultaneous R Ã 2 and fat evaluation. 9,14,[35][36][37] The major advantage of GRE-based sequences, especially those using a 3D acquisition, over SVS is that simultaneous fat and iron quantification can be performed for the whole liver in one breathhold, in a clinical setting. However, separating the fat and water signal contributions may be challenging with iron overload.…”
Section: Discussionmentioning
confidence: 99%
“…Die NAFLD ist mit Insulinresistenz assoziiert und tritt meist zusammen mit Adipositas auf; sie wird daher auch als hepatische Manifestation des metabolischen Syndroms bezeichnet [2]. Durch die hohe Adipositas-Prävalenz weltweit ist das Vorkommen der NAFLD in den letzten Jahrzehnten erheblich angestiegen und liegt in der deutschen Bevölkerung aktuell bei 42,2 % [3,4].…”
Section: Introductionunclassified