Prevalence of depression and its associated factors among patients with diabetes mellitus at Tirunesh-Beijing general hospital, Addis Ababa, Ethiopia

Engidaw, Nigus Alemnew; Wubetu, Abate Dargie; Basha, Elyas Admasu

doi:10.1186/s12889-020-8360-2

Cited by 30 publications

(52 citation statements)

References 24 publications

(24 reference statements)

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“…Our study showed that glycaemic control was not a significant risk for developing depression among patients with T2DM. This is a similar outcome to the non-significant association of depression and glycaemic control using fasting blood sugar as reference in patients with T2DM found in Ethiopia [ 31 , 45 ] and subjects with DM in Nigeria [ 43 ]. In contrast, a significant difference between depression and poor glycaemic control (HbA1c > 7%) among patients with DM was documented in Sudan [ 23 ], Guinea [ 39 ], Ghana [ 19 ] and South Africa [ 40 ].…”

Section: Discussionsupporting

confidence: 82%

Prevalence of depression and associated factors among patients with type 2 diabetes mellitus in eastern Sudan

et al. 2021

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Background Diabetes mellitus (DM) represents a global health threat and burden. It is associated with medical and psychological complications, especially depression. Depression among patients with DM may affect the general prognosis. Hence, we conducted a cross-sectional study in Gadarif, eastern Sudan to evaluate the prevalence of depression and its associated factors among patients with type 2 DM (T2DM). Methods We performed a cross-sectional study. Data on anthropometric parameters, demographic characteristics and blood glucose levels were collected via questionnaire. Depression was assessed using the Patient Health Questionnaire (PHQ-9). Results Three hundred and fifty patients with T2DM were enrolled in the study and 205 (58.6%) were women. The median (interquartile range) age and duration of diabetes were 56.0 (14.0) years and 8 (8) years, respectively. The prevalence of depression in patients with T2DM was 35.6%. Logistic regression analysis showed significant associations between depression and rural residence (adjusted odds ratio [AOR] = 2.11, 95% confidence interval [CI] = 1.20–3.72), non-employee (AOR = 2.32, 95% CI = 1.34–4.00), co-morbidity (AOR = 2.35, 95% CI = 1.43–3.86) and obesity AOR = 2.19, 95% CI = 1.48–4.18). Conclusion The prevalence of depression is high among Sudanese patients with T2DM. Rural residence, unemployment, co-morbidity and obesity are significant risk factors for developing depression among patients with T2DM.

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Section: Discussionsupporting

confidence: 82%

Prevalence of depression and associated factors among patients with type 2 diabetes mellitus in eastern Sudan

et al. 2021

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“…Such a problem negatively impacts communities' health status, resulting in a destructive consequence on mental health status. This doubles the problem for patients and people around them, resulting in irrevocable consequences on countries' health systems (Engidaw et al, 2020). However, diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia that causes carbohydrate, protein, and fat metabolism disorders (WHO, 2016;Lebovitz, 2000;Anderson et al, 2001).…”

Section: Introductionmentioning

confidence: 99%

Meta-analysis of studies on depression prevalence among diabetes mellitus patients in Africa

Ogunsakin

Olugbara²,

Moyo³

et al. 2021

Heliyon

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Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion or insulin action. It can be caused by the consumption of carbohydrate meals or medication side effects. Depression as a comorbid condition in an individual with diabetes is accountable for increased disability, mortality, and significant health problem in patients. As a continent, Africa does not have an overall estimation of depression prevalence among diabetes mellitus patients at a regional level. Consequently, this study's purpose was to use the meta-analysis method to summarize estimates of extant studies that have reported depression prevalence among patients with diabetes mellitus in Africa. The literature search method was executed to classify studies with reported depression prevalence with evidently designed inclusion and exclusion criteria. In total, 20 studies from sundry screened articles were appropriate for ultimate inclusion in the meta-analysis. Since substantial heterogeneity was expected, a random-effects meta-analysis was carried out using the number of cases with a total sample size to estimate the prevalence of diabetes mellitus at a regional level. The residual amount of heterogeneity was found to be high according to the statistics of τ 2 ¼ 0.06; I 2 ¼ 99.10%, chi-square ¼ 2184.85, degree of freedom ¼ 19 and P ¼< 0.001. The pooled depression prevalence was 40% within a 95% confidence interval of 29%-51%. The meta-regression analysis result showed that none of the included moderators contributed to the heterogeneity of studies. The result of effect size estimates against its standard error showed publication bias with a P-value of 0.001. The meta-analysis findings of this study have indicated that depression prevalence in Africa is still high. Reporting on numerous risk factors like socio-demographic characteristics were not possible in this study because of a lack of completeness in the included articles. Consequently, screening diabetes patients for comorbid depression with its associated risk factors is highly recommended.

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“…4 Despite this, a systematic review on prevalence and related acute and chronic complications shows insufficient priority given to diabetes and interventions to prevent acute and long-term complications are lacking in Ethiopia at a national level with the major focus of the country on combating infectious disease. 5,6 Depression is a state of depressed mood, low energy and poor concentration, feelings of guilt or low self-worth, loss of interest or pleasure, disturbed sleep or appetite, and aversion to activity affecting a person's behavior and feelings, thoughts, and sense of wellbeing. 7,8 It is the second leading cause of burden of disease, with around 340 million people of all ages suffering from depression globally.…”

Section: Introductionmentioning

confidence: 99%

“…20 In general, a number of studies showed that the presence of untreated depression in patients with DM is associated with the burden of complications, financial stress, poor overall health status, poor glycemic control, decreased the quality of life and increases mortality. 6 Given one of the top five countries with the highest number of people affected by DM in sub-Saharan Africa (SSA) and depression, contributing the highest share of burden compared to other forms of mental disorders, 9 there is limited information regarding the status of depression specifically among T2DM patients in Ethiopia. Hence, the purpose of this study was to determine the magnitude of untreated depression and associated factors among people living with T2DM at an outpatient diabetic clinic in Halaba Kulito General Hospital, Southern Ethiopia.…”

Section: Introductionmentioning

confidence: 99%

<p>Factors Associated with Untreated Depression Among Type 2 Diabetic Patients at Halaba Kulito Hospital, South Ethiopia: A Cross-Sectional Study</p>

Azeze¹,

Adema²,

Adella³

et al. 2020

DMSO

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Background: Depressed type 2 diabetes mellitus patients (T2DM) show poorer compliance with treatment and self-care recommendations than non-depressed T2DM patients. This contributes to poor prognosis and accelerates diabetic-related complications including poor glucose regulation, diabetic retinopathy, neuropathy, nephropathy, and escalated healthcare expenditure. Objective: This study aimed to determine the magnitude of untreated depression and associated factors among people living with T2DM at outpatient diabetic clinic in Halaba Kulito General Hospital, Southern Ethiopia. Methods: Institution-based cross-sectional study was conducted from November 1 to December 15, 2019 at Halaba Kulito Hospital, Southern Ethiopia. We collected data by faceto-face interview with patient record review. A total of 418 type 2 diabetic patients were systematically selected and interviewed using a pretested structured questionnaire. We used a composite score of nine-items Patient Health Questionnaire (PHQ-9) to assess depression status. Descriptive statistics was used to summarize respondents' background characteristics. Logistic regression analysis was done to identify associated factors with the outcome variable. Levels of significance were set at 5% (P<0.05). Results: The finding depicted that 120 (29.3% with 95% Confidence interval (CI) = 25.0%, 34.0%) study participants satisfied diagnostic criteria for depression disorder. After controlling for confounding effect, we identified being hypertensive (Adjusted Odds Ratio (AOR) = 5.66; 95% CI: 3.24, 9.86), having no child (AOR = 3.32; 95% CI: 1.88, 5.86), and poor glycemic control (AOR = 6.23; 95% CI: 3.65, 10.54) as risk factors for untreated depression among people with type 2 diabetes. Conclusion: Findings of this study indicate that untreated depression among type 2 diabetic patients is high. Poor glycemic control, not having a child and having hypertension were among significantly associated factors with depression. These results suggest much need for interventions, including strong medication adherence and self-care activities such as exercise or healthful diet for optimal glycemic control.

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Prevalence of depression and its associated factors among patients with diabetes mellitus at Tirunesh-Beijing general hospital, Addis Ababa, Ethiopia

Abstract: Background: Depression is one of the common and overwhelming mental disorder in diabetic patients. A little is known about the prevalence and associated factors of depression among diabetic patients at general hospitals.

Cited by 30 publications

References 24 publications

Prevalence of depression and associated factors among patients with type 2 diabetes mellitus in eastern Sudan

Prevalence of depression and associated factors among patients with type 2 diabetes mellitus in eastern Sudan

Meta-analysis of studies on depression prevalence among diabetes mellitus patients in Africa

<p>Factors Associated with Untreated Depression Among Type 2 Diabetic Patients at Halaba Kulito Hospital, South Ethiopia: A Cross-Sectional Study</p>

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