Prevalence of Age-Related Macular Degeneration in Portugal: The Coimbra Eye Study - Report 1

Abstract

Purpose: To evaluate the age- and gender-specific prevalence of early and late age-related macular degeneration (AMD) in a Portuguese population-based sample. Methods: All patients aged ≥55 years of a Portuguese primary health-care unit were recruited for a cross-sectional population-based study. Responders underwent complete ophthalmological examination and digital fundus imaging. Early and late AMD was defined according to the International Age-Related Macular Epidemiological Study Group Classification, and the adopted staging for AMD was the same as that used in the Rotterdam study. The age- and gender-adjusted prevalence of early and late forms of AMD was calculated. Results: Of the 4,370 eligible subjects, 3,000 underwent study procedures (68.6% response rate) and 2,975 were included in the analysis; they had a mean age of 68.9 ± 8.6 years. The overall prevalence of early and late AMD was 15.53% (95% CI 14.25-16.88) and 0.67% (95% CI 0.41-1.04), respectively. Neovascular AMD (NV-AMD) and geographic atrophy (GA) accounted for 0.44% (95% CI 0.23-0.75) and 0.27% (95% CI 0.12-0.53) of individuals, respectively. The highest prevalence of advanced AMD was among those aged ≥75 years (1.13% for NV-AMD; 0.63% for GA). Conclusions: To our knowledge, this is the first AMD epidemiological study in a Portuguese population. The early forms of the disease had a similar prevalence to that of other large-scale population-based cohorts, but late AMD was less frequent than previously reported.

Burden and predictors of age-related macular degeneration among old age patients with diabetes attending comprehensive specialised hospitals in Northwest Ethiopia: a multicentre cross-sectional prospective study

“…The burden of AMD in this study was 15.4% (95% CI 13.0% to 18.0%). This study result was in line with previous studies from Portugal at 16.2% 19 and China 17.3%. 20 Similarity in population type (diabetic population), in the Chinese study and the current study, could explain the comparability of results.…”

Burden and predictors of age-related macular degeneration among old age patients with diabetes attending comprehensive specialised hospitals in Northwest Ethiopia: a multicentre cross-sectional prospective study

“…The burden of AMD in this study was 15.4% (95% CI 13.0% to 18.0%). This study result was in line with previous studies from Portugal at 16.2% 19 and China 17.3%. 20 Similarity in population type (diabetic population), in the Chinese study and the current study, could explain the comparability of results.…”

Cross-sectional study investigating the prevalence and causes of vision impairment in Northwest Portugal using capture–recapture

“…Our results for the older population are also in line with the estimates from a recent meta-analysis estimating the prevalence of VI in people 55 years or older in European countries. The study that included data from Portugal, estimated an overall prevalence of VI for those above 55 years close to 2.75% 49 50. For age under 25 years, the prevalence of VI in our study was low and in line with several other studies 51–53.…”

A cross-sectional study investigating the prevalence and causes of vision impairment in Northwest Portugal using capture-recapture

“…Our results for the older population are also in line with the estimates from a recent meta-analysis estimating the prevalence of VI in people 55 years or older in European countries. The study that included data from Portugal, estimated an overall prevalence of VI for those above 55 years close to 2.75% [47,48]. For age under 25 years, prevalence of VI in our study was low and in line with several other studies [49][50][51].…”

Burden and predictors of age-related macular degeneration among old age patients with diabetes attending comprehensive specialised hospitals in Northwest Ethiopia: a multicentre cross-sectional prospective study

“…The burden of AMD in this study was 15.4% (95% CI 13.0% to 18.0%). This study result was in line with previous studies from Portugal at 16.2% 19 and China 17.3%. 20 Similarity in population type (diabetic population), in the Chinese study and the current study, could explain the comparability of results.…”

Cross-sectional study investigating the prevalence and causes of vision impairment in Northwest Portugal using capture–recapture

“…Our results for the older population are also in line with the estimates from a recent meta-analysis estimating the prevalence of VI in people 55 years or older in European countries. The study that included data from Portugal, estimated an overall prevalence of VI for those above 55 years close to 2.75% 49 50. For age under 25 years, the prevalence of VI in our study was low and in line with several other studies 51–53.…”

A cross-sectional study investigating the prevalence and causes of vision impairment in Northwest Portugal using capture-recapture

“…Our results for the older population are also in line with the estimates from a recent meta-analysis estimating the prevalence of VI in people 55 years or older in European countries. The study that included data from Portugal, estimated an overall prevalence of VI for those above 55 years close to 2.75% [47,48]. For age under 25 years, prevalence of VI in our study was low and in line with several other studies [49][50][51].…”

Burden and predictors of age-related macular degeneration among old age patients with diabetes attending comprehensive specialised hospitals in Northwest Ethiopia: a multicentre cross-sectional prospective study

“…The burden of AMD in this study was 15.4% (95% CI 13.0% to 18.0%). This study result was in line with previous studies from Portugal at 16.2% 19 and China 17.3%. 20 Similarity in population type (diabetic population), in the Chinese study and the current study, could explain the comparability of results.…”

Cross-sectional study investigating the prevalence and causes of vision impairment in Northwest Portugal using capture–recapture

“…Our results for the older population are also in line with the estimates from a recent meta-analysis estimating the prevalence of VI in people 55 years or older in European countries. The study that included data from Portugal, estimated an overall prevalence of VI for those above 55 years close to 2.75% 49 50. For age under 25 years, the prevalence of VI in our study was low and in line with several other studies 51–53.…”

A cross-sectional study investigating the prevalence and causes of vision impairment in Northwest Portugal using capture-recapture

“…Our results for the older population are also in line with the estimates from a recent meta-analysis estimating the prevalence of VI in people 55 years or older in European countries. The study that included data from Portugal, estimated an overall prevalence of VI for those above 55 years close to 2.75% [47,48]. For age under 25 years, prevalence of VI in our study was low and in line with several other studies [49][50][51].…”