Prevalence and Treatment of Psoriasis in the United Kingdom

Abstract

Setting: Outpatient practices of general practitioners. Patients: We included in the analysis all patients who were registered with a general practitioner in the General Practice Research Database from 1987 to 2002. Main Outcome Measures: The prevalence and treatment of psoriasis. Results: We identified 114 521 patients with psoriasis of a total population of 7 533 475 patients, yielding a prevalence of 1.5%. The prevalence of psoriasis increases more rapidly in young female patients compared with young male patients and declines significantly in patients 70 years and older, regardless of sex. Overall, 91.8% of patients with a diagnosis of psoriasis received a prescription for psoriasis treatment on or after the date of their first diagnostic code of psoriasis in the General Practice Research Database. Most of the patients (55.2%) received only 1 or 2 prescriptions for psoriasis in the first year after psoriasis was documented in the General Practice Research Database. Conclusions: The epidemiology of psoriasis in the General Practice Research Database population is similar to that of other epidemiologic studies of psoriasis performed in the United Kingdom, the United States, and other Western countries. Psoriasis carries a substantial burden given its high prevalence and its associated need for prescription therapy. Additional studies are necessary to determine why the prevalence of psoriasis increases more rapidly in female patients and to determine why the prevalence decreases in patients 70 years and older.

Incidence, prevalence and mortality of patients with psoriasis: a U.K. population-based cohort study

“…In early‐onset psoriasis, females have a higher incidence of psoriasis and the peak of early‐onset psoriasis occurs in their late teens and early twenties. This pattern reflects previously reported more rapid increase in psoriasis prevalence in women 27. The corresponding peak of early‐onset psoriasis in men appeared later – in their thirties.…”

Retrospective Analysis of Clinical and Sociodemographic Features of Patients with Psoriasis

“…Danimarka'da sıklık oranı erkeklerde %3,2, kadınlarda %2,5 olarak bulunmuştur (7) . Diğer ülkelerdeki oranlar sırası ile İsveç'te %1,4, İngiltere'de %1,5 ila 2,8, Almanya'da %6,5 ve İspanya'da %3,7'dir (7,8) . Ülkemizdeki prevalans ise %0,7 ila %1,88 arasında bildirilmiştir (9,10,11) .…”

Investigação de infecção tuberculosa latente em pacientes com psoríase candidatos ao uso de drogas imunobiológicas

“…The incidence of depression in psoriasis patients is around 24%, with improvement of the lesions being usually accompanied by relief of this condition. 2,3 Based on the similarity of the immunological factors responsible for the formation of atheromatous plaques and those involved in the installation and progression of chronic inflammatory diseases such as psoriasis, it was possible to establish a relationship with the incidence of cardiovascular diseases. Corroborating these findings, patients with severe psoriasis present a high incidence of psoriatic arthritis, cardiovascular disease, hypertension, obesity, diabetes and increased risk of acute myocardial infarction.…”