Prevalence and relevance of allergic reactions in patients patch tested in North America—1984 to 1985

Storrs, Frances J.; Rosenthal, Lawrence E.; Adams, Robert M.; Clendenning, William E.; Emmett, Edward A.; Fisher, Alexander A.; Larsen, Walter G.; Maibach, Howard I.; Rietschel, Robert L.; Schorr, William F.; Taylor, James S.

doi:10.1016/s0190-9622(89)70129-8

Cited by 127 publications

(35 citation statements)

References 8 publications

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“…1,10,19 When the occupations of dermatitis patients were questioned in our study, the first place was taken by the housewives.…”

Section: Discussionmentioning

confidence: 99%

“…15 Zug et al detected positivity in ratios of 28,3% nickel sulfate, 17,9% cobalt chloride, 15,3% thimerosal in their test on 391 contact dermatitis patients. 16 Demirgüneş et 19 Storrs et al reported sensitivities against nickel, parefenilendiamin quaternium-15 and neomycin as a result of the patch test on contact dermatitis patients. 20 Rui et al detected positivity in the ratios of 24,6% for nickel sulfate, 10,2% for cobalt chloride and 8,7% for potassium dicromat.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

•Evaluation of patch test results in patients with contact dermatitis

Yeşilova¹

2011

Dicle Med J

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ÖZETAmaç: Yama testi, allerjik kontakt dermatit tanısını doğ-rulayan ve kontakt allerjinin sebebini bulmamızı sağlayan en önemli tanısal yöntemdir Retrospektif olarak yapılan çalışmamızda, bölgemizde kontakt dermatitli hastaların yama testi sonuçlarının değerlendirilmesi amaçlanmıştır. Gereç ve yöntem:Kontakt dermatit tanısı alan hastaların 84'ü (%56) kadın, 66'sı (%44) erkek, toplam 150 hastaya Avrupa standart test serisi ile yama testi yapıldı. Test, Uluslararası Kontakt Dermatitis Araştırma Grubu tarafın-dan standardize edilmiştir. Bulgular:Lezyonların en sık ellerde (%36) yerleştiği gö-rüldü. 31''i kadın (%58,4), 21'i erkek (%41,6) olmak üzere toplam 72 hastada (%48) bir veya birden fazla maddeye karşı pozitif allerjik reaksiyon elde edildi. En sık reaksiyon saptanan allerjenler ise nikel sülfat (%13,3), potasyum dikromat (%11,3) ve kobalt klorid (%8,6) idi.Sonuç: Kontak dermatite nikel hassasiyetinin daha fazla olduğu bulundu. Sağlıklı kontrollerle karşılaştırıldığında kontakt dermatiti hastalarda deri yama testini daha sık görülmüştür. Anahtar kelimeler: Kontakt dermatit, yama testi, nikel sülfat ABSTRACTObjectives: Patch test is the most reliable method to diagnose allergic contact dermatitis and to find out the responsible contact allergen. The aim of this retrospective study was to evaluate the patch test results of patients with contact dermatitis in our region. Materials and methods:One Hundred fifty patients (84 female and 66 male) with contact dermatitis were patch tested with European standard test series. The testing has been standardized by the international Contact Dermatitis Research Group (ICDRG).Results: A majority of the lesions (36%) were localized on the hands. In 31 female (58,4%) and 21 male (4,6%) patients (a total of 72 patients) there were positive allergic reactions to at least one chemical. Nickel sulphate (13,3%), potassium dichromate (11,3%) and cobalt chloride (8,6%) were the most often allergens reacted. Conclusion:Nickel sensitivity is more common. Comparing with healthy controls contact sensitization may be more prevalent in patients with contact dermatitis.

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“…1,10,19 When the occupations of dermatitis patients were questioned in our study, the first place was taken by the housewives.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

•Evaluation of patch test results in patients with contact dermatitis

Yeşilova¹

2011

Dicle Med J

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“…Thus, the DGEBA epoxy resin, because it is one of the top 20 contact allergens, was induded in the European standard patch-test series in 1966 (Jolanki 1991). In the 1970S and 1980s, the North American Contact Dermatitis Group (NACDG) patch tested approximately 9000 patients for allergic contact dermatitis and found that 2-3% were allergic to the standard epoxy resin (Rudner 1977;Lynde et al 1982;Storrs et al 1989); in the beginning of the 1990S, the positive response was 1.8% among 3500 patients studied (Marks et al 1995). Edman (1988) found a lower frequency, namely 1%, among 3562 patients patch tested during 1982-1987 at the Malmö General Hospital, Sweden.…”

Section: Diglycidyl Ether Of Bisphenol a (Dgebaj Epoxy Resinsmentioning

confidence: 99%

Epoxy Resins

Jolanki¹,

Kanerva²,

Estlander³

2000

Handbook of Occupational Dermatology

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“…Among the aromatic compounds with ortho or para substituents, however, there are differences in the per centages of positive reactions observed [1- 3,10]. Such differences may be related to the rate of oxidation of the compounds and, therefore, to the amount of quinone generated in the same period [11], To evaluate if the patch test responses correlate to the chemical structure of the aromatic compounds, in patients positive to at least one hapten of the para group, the number of positive reactions to freshly prepared PPD and to structurally related haptens was compared with the rate of auto-oxidation.…”

Section: Introductionmentioning

confidence: 99%

Study on Cross-Reactivity to the Para Group

et al. 1990

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In 80 patients, positive to at least one hapten of the para group (para-phenylenediamine, diaminodiphenylmethane, benzocaine, PPD mix), patch tests were carried out with freshly prepared solutions of para-phenylenediamine (PPD) and of 3 selected aromatic compounds related structurally to PPD (para-aminophenol, ortho-aminophenol, hydroquinone). The number of positive reactions correlated with the rate of decomposition of the substances as evaluated by high-pressure liquid chromatography. PPD, which was almost decomposed after 24 h, gave the highest number of positive reactions, followed by ortho-aminophenol and by para-aminophenol, while hydroquinone, which was oxidized to the extent of 35% did not give any reactions. To evaluate if a different rate of oxidation can modify the patch test response in the same patients and in 10 normal volunteers tests were carried out with PPD solutions containing the oxidizing agent silver oxide (0.1%). By this procedure a significant increase in the number of positive responses was observed. The results suggest that the rate of decomposition and therefore the amount of quinone(s) generated, might be the key to eliciting patch test responses to oxidizable aromatic haptens.

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Prevalence and relevance of allergic reactions in patients patch tested in North America—1984 to 1985

Cited by 127 publications

References 8 publications

•Evaluation of patch test results in patients with contact dermatitis

•Evaluation of patch test results in patients with contact dermatitis

Epoxy Resins

Study on Cross-Reactivity to the Para Group

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