•Evaluation of patch test results in patients with contact dermatitis

Yeşilova, Yavuz

doi:10.5798/diclemedj.0921.2011.04.0068

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…Similar results have been described by several authors (7,9,17). In addition, face was more affected in first group and feet were more affected in the second.…”

Section: Discussionsupporting

confidence: 91%

Influence of Age on Patch Tests Results

Mahfoudh¹,

Elmaleel²,

Kalboussi³

et al. 2017

tdd

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Amaç: Yama test sonuçları üzerinde yaşın etkisini incelemek ve yaş gruplarına göre deri duyarlaştırıcılarının profillerini karşılaştırmaktır. Yöntemler: Bu sekiz yıllık retrospektif çalışma, Tunus, Sousse Üniversite Hastanesi, Meslek Hekimliği Bölümü, Dermatoloji ve Alergoloji Ünitesi'nde alerjik kontakt dermatit hastalarının tüm tıbbi kayıtlarını içermektedir. Çalışma popülasyonu iki yaş grubuna ayrıldı (grup 1: <40 yaş hastalar; grup 2: >40 yaş hastalar). İstatistiksel anlamlılık derecesi p<0,05 olarak kabul edildi. Bulgular: Beş yüz altmış sekiz hasta en az bir yama testine pozitif reaksiyon vermiştir. Yaşlı bireylerin en az bir yama testine pozitif yanıt vermeleri gençlere göre 1,1 kat daha muhtemeldir. İki grupta da görülen en yaygın alerjenler: potasyum dikromat (%34,2, %38), tiuram karışımı (%6, %11), kobalt klorür (%27, %28,8), Peru balsamı (%6, %11,3) ve nikel sülfattır (%41, %27,3). Potasyum dikromat ile deri reaksiyonlarının intansitelerinde belirgin bir varyasyon not edildi (p=0,00). Sonuç: Yama test sonuçları üzerinde yaş etkisinin fizyolojik mekanizmasının aydınlığa kavuşturulması ve European Standard Battery'yi alerji tipi ve uygun konsantrasyonlar açısından her yaş grubuna uyarlamak için daha fazla çalışmaya gereksinim vardır. Anahtar kelimeler: Yama testleri, alerjen, dermatit, yaş, deri reaksiyonları, deri Öz AbstractObjective: To assess the influence of age on the patch-test results and to compare the profiles of skin sensitizers according to the age groups. Methods: It is an 8-year retrospective study involving entire medical records of the patients with allergic contact dermatitis at the Unity of Dermatology and Allergology in the Department of Occupational Medicine, University Hospital of Sousse in Tunisia. Study population was divided into two age groups (group 1: patients <40 years; group 2: patients >40 years). The statistical significance level was taken as p<0.05. Results: Among the patients, 586 have had at least one positive reaction to the patchtest. Older individuals were 1.1 times more likely to have at least one positive reaction to the patch-test than younger ones. The most common allergens in both groups are potassium dichromate (34.2% vs. 38%), thiuram mix (6% vs. 11%), cobalt chloride (27% vs. 28.8%), balsam of Peru (6% vs. 11.3%) and nickel sulphate (41% vs. 27.3%). A significant variation was noted for potassium dichromate in terms of intensity of skin reaction (p=0.00). Conclusion: More research is needed to elucidate the physiologic mechanisms of age on the patch-test results and to adapt the European Standard Battery to each age group in term of allergen type and their appropriate concentration.

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“…Similar results have been described by several authors (7,9,17). In addition, face was more affected in first group and feet were more affected in the second.…”

Section: Discussionsupporting

confidence: 91%

Influence of Age on Patch Tests Results

Mahfoudh¹,

Elmaleel²,

Kalboussi³

et al. 2017

tdd

View full text Add to dashboard Cite

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Screening for Allergic Contact Dermatitis Based on Pattern of Patch Test Results: A Retrospective Study

Alshamrani,

Alhothali,

Alyemani

et al. 2023

Journal of Dermatology and Dermatologic Surgery

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Background: Contact allergies are associated with morbidity worldwide. Purpose: To investigate the patterns of sensitization to contact allergens in a local population. Methods: A retrospective study investigated patch test reactivity among patients with a clinical diagnosis of contact dermatitis referred to the dermatology clinic at King Fahad Armed Forces Hospital, Jeddah, between January 2021 and January 2023. Pregnant women, immunosuppressed patients, and those receiving immunosuppressive therapy were excluded. Only 92 of 101 referred patients underwent patch testing after fulfilling requirements. The patch test was performed using a Thin-layer Rapid-Use Epicutaneous patch test containing 35 contact allergenic elements and one control (total = 36). Results: Among 92 patients, 35 (38%) were males, and 57 (62%) were females. Of these, 62 (67.4%) patients had a positive patch test and reacted to one or more allergens. The most common sensitizing allergens were p-phenylenediamine (PPD), gold sodium thiosulfate, and disperse blue 106, with equal positive reactions in 16 (25.8%) patients, followed by nickel sulfate in 13 (21%), p-tert-butylphenol formaldehyde resin in eight (13%), fragrance mix in 7 (10.8%), and epoxy resin in six (9.2%) patients. No significant sex differences were found among patients with contact dermatitis where notable patch test allergen reactivity was observed. Conclusion: Patch test reactivity to PPD, gold sodium thiosulfate, and disperse blue 106 was high. The pattern of contact allergy observed here highlights the need for large-scale investigations to identify local allergens for contact allergy and formulate policies for avoiding exposure.

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•Evaluation of patch test results in patients with contact dermatitis

Cited by 2 publications

References 11 publications

Influence of Age on Patch Tests Results

Influence of Age on Patch Tests Results

Screening for Allergic Contact Dermatitis Based on Pattern of Patch Test Results: A Retrospective Study

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