Prevalence and pattern of thyroid malignancy in thyroid nodule in Aseer Central Hospital in KSA

Abstract

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Thyroid nodules are common in the general population, especially in women. Non palpable nodules are often found when patients undergo diagnostic imaging such as ultrasonogra­phy and computed tomography of the chest and neck. This retrospective study to assess the Prevalence of thyroid malignancy in thyroid nodule related to gender, age, and pathology, in Aseer Central Hospital KSA. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">During a 5-year period (2011–2016), the medical records of 319 patients with thyroid nodules were collected from the department of pathology at Aseer Central Hospital KSA. The cases were reviewed for data on gender, age, and the pathological result. All patients underwent hemi or total thyroidectomy. Comparisons between genders, age groups, and tissue origins were performed. All statistical tests were performed with SPSS software. </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Over a period of 5 years, a total of 319 patients: male 17.2% and female 82.8% Underwent for hemi or total thyroidectomy. The age of presentation was ranging from 14 to 80 years. Among the 319 cases of thyroid nodules 73.7% were benign nodules and 26.3% malignant nodules. Papillary thyroid carcinoma in 72.6%, follicular thyroid carcinoma 10.6%, Hurthle cell carcinoma 4.8%, anaplastic carcinoma 4.8%, thyroid lymphoma 4.8% and medullary thyroid carcinoma in 2.4%. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Thyroid nodule is a common clinical problem and the proportion of such nodules that prove to be malignant is not small, investigations are of immense help to corroborate with the clinical and morphological finding. Papillary thyroid carcinoma most common malignant thyroid carcinoma followed by follicular thyroid carcinoma, hurthel cell carcinoma, anaplastic thyroid carcinoma, lymphoma and finally medullary thyroid Carcinoma. No significant different between male and female as risk factors for malignancy.</span></p>

Thyroid Swellings Undergoing Thyroidectomy in a Tertiary Hospital of Nepal: A Retrospective Study of Distribution and Prevalence of Malignancy

“…There was notable female predilection in this study which was seemingly following existing literature. 7,11,12 In contrast to earlier findings of colloid goiter as the most common pre-operative FNAC finding, we did not replicate similar observations. Current study found out that majority of lesion were preoperatively diagnosed as papillary carcinoma (42%), however, this doesn't imply that majority of lesion pre-operatively were malignant in nature.…”

“…9,10 The mean age of patients recruited in this study was similar to Pradhan et al 9 Most subjects recruited in the current study presenting with thyroid nodules were in the fifth decade, which did not corroborate previous studies. 5,7,11 Only patients with multinodular goiter were included in similar studies conducted in Nepal. 5,7 Majority of females in the current study fell into the age group 21-30 years and did not follow the finding of Shrestha et al 4 We observed similar discordance in the distribution of males according to age group.…”

Histopathological Spectrum of Thyroid Lesions- A Two Years Study

“…3 Most of the thyroid disorders are benign in nature and thyroid enlargements are seen more common in females than in males. 4 Thyroid gland disorders usually manifests as enlargement of the thyroid gland (goiters) or as variations in hormone levels or as both. Around 4%-5% of the population present with clinically as externally visible nodules of the thyroid.…”