Prevalence and Antimicrobial Susceptibility of Pathogens in Urinary Tract Infections

Abstract

This study was done to assess the bacterial profile and antibiotic susceptibility pattern of urinary tract infections (UTIs) pathogens. For proper identification of causative microbial agents, mid stream urine samples from 459 patients with clinical symptoms suspected to be UTI were collected, cultured and subjected to appropriate biochemical tests. These samples were collected from Teaching Laboratories Center in Baghdad during the study period (1 st January 2009-1 st July 2009). The antimicrobial sensitivity test was carried out by disc diffusion technique using Muller-Hinton agar. 100 urine samples were cultured positive with a colony count equal or more than 10 5 /ml while 359 cases were excluded as they were culture negative or exhibited mixed infections. Overall males to females ratio was 1:3.2. The most prevalence isolates were Escherichia coli with frequency rate of 50% followed by Enterobacter spp.(12%). Whereas, Klebsiella spp., Pseudomonas aeruginosa and Enterococcus faecalis showed frequency rate of 9% for each. Howevere, Proteus spp., Staphylococcus aureus, Staphylococcus epidermidis and Acinetobacter spp.showed frequency rate less than 5%. The majority of isolates were sensitive to imipenem (96%) followed by amikacin(89%) and nitrofurantion(69%) whereas, high level resistance was seen to cotrimoxazole, ampicillin and trimethoprim followed by cefoxitin, nalidixic acid, gentamicin and cefotaxime in decreasing order of frequency.

Antibiotic Susceptibility of Pathogens in Urinary Tract Infections in Community

“…The overall males to females ratio were (1:14). This fi nding was consistent with other reported studies from many parts of the world showing a statistically predominance of females [16][17][18][19]. This is usually related to the anatomical and pathogenic factors of females [20].…”

Antimicrobial Susceptibility Pattern of Pathogenic Bacteria Causing Urinary Tract Infections at Azadi Hospital In Duhok City\Kurdistan Region of Iraq

“…in the study. Whereas, a studies showed that the second most common uropathogen in Baghdad and Tikrit were Enterobacter spp and Proteus mirabilis respectively (Mahmood, 2011;Al-Jebouri and Mdish, 2013). In this study, the predominance incidence of infection was in females (73.3%).…”

“…A major worldwide problem nowadays is the resistance of the invading microorganisms to the treatment; resistant organisms have emerged due to several factors related to the genetic nature of the organisms and selective antimicrobial pressure in humans (Saffar et al, 2008;Habeeb et al, 2014;Hussein et al, 2017). Globally UTIs area serious health problem which affects millions of peoples every year (Mahmood, 2011).Worldwide, UTI is identified in about 150 million people annually (Gupta et al, 2001). About 40% of all hospital acquired infections are due to UTIs which are catheter associated (Ruden et al, 1997).About 25% of patients who subjected to urinary catheter for one week or more developed bacteriuria with a daily risk of 5-7% (Maki and Tambyah, 2001).…”

Relationship among Some Immunoglobulins, Complement Protein C3 and Urinary Tract Infection of Women Caused by Gram Negative Bacilli in Kirkuk, Iraq

“…About 10.8 million patients in United States visited an emergency development for treatment of UTI (Sammon et al, 2014). Bacterial organisms which cause UTI may involve Escherichia coli, Klepsiella, Pseudomonas, Proteus mirabilis and Enterococcus fecalis (Mahmood, 2011;Dromigny, 2005).…”