Abstract:The clot retracting activity (CRA) of frozen platelets was studied as the in vitro test best representing the functional "integrity" of platelets. Dimethylsulfoxide as an additive in the preservation by freezing of platelets acts most effectively in the presence of plasma. Freezing of the platelets in a suspending medium consisting of 50 per cent plasma in saline with 15 per cent DMS, resulted in a 10 to 15 per cent loss over the fresh control CRA values. Freezing rates ranging from 3 C. to 30 C. per minute ca… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.