Preparation of well-controlled three-dimensional skeletal hybrid monoliths via thiol–epoxy click polymerization for highly efficient separation of small molecules in capillary liquid chromatography

Thermogravimetric characterization of ex situ polymethacrylate (EDMA‐co‐GMA) monoliths

“…This can be determined through the kinetic triplet E a , A, and . In addition, predictions made based on these analyses are critical in estimating the lifespan and compositions outside the current experimental analysis . The equations employed for kinetic study are fundamentally hinged on a single step equation: where β is the heating rate, α is the extent of conversion, T is absolute temperature in K, and is the reaction model.…”

“…It was observed that the degradation of the acrylamide copolymers were dependent on the type of monomers and their moiety. Likewise, various characteristic temperatures have been observed as the thermally stable point beyond which depolymerization occurs leading to the loss of chemical signature for the following types of monoliths: HMA‐co‐EDMA methacrylate monolith, 210 °C; poly(divinylbenzene) monolith, 380 °C; poly(g‐glutamic acid) monolith, ∼230 °C; and POSS‐epoxy‐TPTM hybrid monolith, 300 °C …”

Advances in the development and applications of organic–silica hybrid monoliths

“…Further surface modification with stearyl or benzyl methacrylate by thiol‐ene click chemistry afforded even more hydrophobic columns for reversed‐phase separations and columns modified with [2‐(methacryloyloxy)ethyl]‐dimethyl‐(3‐sulfopropyl)‐ammonium hydroxide for HILIC . A one‐pot approach based on alkaline‐catalyzed thiol‐epoxy click reaction of POSS‐epoxy and multi‐thiols led to formation of monoliths with bicontinuous morphology exhibiting high column efficiency (182 700 plates/m for butylbenzene in CLC). Large through‐pore to skeleton ratio, and narrow skeleton were reported to be similar to silica‐based monoliths.…”

Recyclable cross-linked hydroxythioether particles with tunable structures via robust and efficient thiol-epoxy dispersion polymerizations

“…This addition is catalyzed by a base, which generates a thiolate anion that opens the epoxide ring via an S N 2-type mechanism. 39,40 Although the thiol-epoxy reaction has been extensively studied and many reports discuss the broad applicability in polymer science, [41][42][43][44][45][46][47][48][49][50][51][52][53][54] the use of this reaction in heterogeneous system has not drawn attention of academia or industry yet. Nevertheless, multiple reasons suggest that the thiol-epoxy reactions is an excellent candidate for particle preparation in heterogeneous system.…”