Preparation of PCL/PVP/Ag Nanofiber Membranes by Electrospinning Method

Abstract

The composite nanofiber membranes of poly (ε-caprolactone)/poly(vinyl pyrrolidone) (PCL/PVP) containing silver nanoparticles were prepared by electrospinning method. The morphology of composite nanofibers was characterized by scanning electron microscopy (SEM). The silver nanoparticles on the electrospun fibers were characterized by X-Ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The contact angle and water uptake of PCL/PVP/Ag nanofiber membranes were measured. The SEM photos indicated that the average diameter of the fibers was significantly decreased with the addition of silver nanoparticles. The X-Ray images showed that Ag nanoparticles were distributed on the surface of nanofiber membranes. When the PVP mole ratio was higher than 15%, the nanofiber membranes showed good hydrophilic property. The PCL/PVP/Ag nanofiber membranes could be applied to prepare wound dressing.

Sabina chinensis leaf extracted and in situ incorporated polycaprolactone/polyvinylpyrrolidone electrospun microfibers for antibacterial application

“…30,31 The hydrophilicity and biodegradability of electrospun PCL micro-and nanobers are improved by incorporating PVP into PCL organic solution. 28,29,[32][33][34][35][36][37] In this study, the solution extracted from fresh leaves of Sabina chinensis by organic solvent at room temperature was directly used as the spinning solvent. PCL and PVP were directly added to the spinning solvent to prepare the spinning solution.…”

Enhanced properties of poly(ε‐caprolactone)/polyvinylpyrrolidone electrospun scaffolds fabricated using 1,1,1,3,3,3‐hexafluoro‐2‐propanol

“…The fabricated materials demonstrated antibacterial activity against Pseudomonas aeruginosa , Staphylococcus aureus , and Escherichia coli . Also, Jia et al obtained PCL/PVP scaffolds containing silver nanoparticles with polymer ratios of 90/10, 85/15, 80/20, and 70/30 from the solution in dichloromethane 26 . Other researchers used dimethylformamide/chloroform (1/4, w/w) mixture for the preparation of PCL/PVP scaffolds doped with silver nanoparticles 27 …”

“…Also, Jia et al obtained PCL/PVP scaffolds containing silver nanoparticles with polymer ratios of 90/10, 85/15, 80/20, and 70/30 from the solution in dichloromethane. 26 Other researchers used dimethylformamide/chloroform (1/4, w/w) mixture for the preparation of PCL/PVP scaffolds doped with silver nanoparticles. 27 Thus, PCL/PVP materials show high potential to be successfully applied in the area of regenerative medicine and drug delivery.…”

Preparation of Lutein-Loaded PVA/Sodium Alginate Nanofibers and Investigation of Its Release Behavior

“…Nanofibers produced by electrospinning exhibit several interesting properties, including high surface area to volume ratio, and void fraction [8], which make electrospinning nanofibers an appropriate candidate as a drug delivery system. Polymeric matrices such as polyvinyl alcohol (PVA), fibrinogen, chitosan, polycaprolactone, and polyvinylpyrrolidone provide an excellent source for electrospinning based on their biocompatibility [9,10]. PVA nanofibers have been widely utilized as potential biomaterials owing to its extraordinary hydrophilicity, biocompatibility and mechanical properties [11,12,13,14].…”