Preparation of molecularly imprinted electrochemical sensor for l-phenylalanine detection and its application

Corrosion protection mechanism of Ce4+/organic inhibitor for AA2024 in 3.5% NaCl

“…59 Another study showed that L-phenylalanine/Ce 4+ improved the corrosion prevention of copper in HCl solution. 36 The authors also related the corrosion inhibition to the formation of a complex; nevertheless, the ease of oxidation of L-phenylalanine in aqueous solution 60 was not taken in consideration.…”

A Review of Sensors and Biosensors Modified with Conducting Polymers and Molecularly Imprinted Polymers Used in Electrochemical Detection of Amino Acids: Phenylalanine, Tyrosine, and Tryptophan

“…The devices obtained demonstrated good sensitivity and selectivity in detecting L-Tyr, having the following detection limits: 8.2 × 10 −8 M for PPy/FeCN-SPCE, 4.3 × 10 −7 M for PPy/NP-SPCE, and 3.51 × 10 −7 M for PPy/SDS-SPCE (as shown in Figure 4) [27]. On the other hand, other polymers involved in numerous studies are MIPs in monomer solutions with template molecules, reticulation agents, or solvents, this being a versatile preparation method that can frequently be used to configure various biomimetic receivers (as shown in Figures 5 and 6) [43,118]. Initially, these MIPs were synthesized by thermal heating, but because of the disadvantages of the long synthesis time and excess internal energy of the system, other methods for the synthesis of MIPs were developed, On the other hand, other polymers involved in numerous studies are MIPs in monomer solutions with template molecules, reticulation agents, or solvents, this being a versatile preparation method that can frequently be used to configure various biomimetic receivers (as shown in Figures 5 and 6) [43,118].…”

“…The unique physical and chemical properties of CPs and MIPs, such as versatility, adaptability, sensitivity, and adjustable architecture, have led many researchers, including our group, to apply and use these new materials to develop novel chemically modified sensors and biosensors [42]. The polymers that were used in sensors were conductor polymers (CPs)-polypyrrole (PPy) [27,28,43,44], poly(3,4ethylenedioxythiophene) (PEDOT) [45,46], polyalanine (PANI) [47], and polythiophene (PT)-and molecularly imprinted polymers (MIPs) [48,49].…”

Surface Plasmon Resonance Based on Molecularly Imprinted Polymeric Film for l-Phenylalanine Detection

“…Although the safe PKU range in plasma is 120–360 µM, doctors trying for the lower portion of this range. For that reason, the desired PKU levels in the plasma is 21–137 μM for infants and children and 35–85 μM for adults [ 11 , 12 ]. For the diagnosis of PKU disease, phenylalanine, known as an indicator substance in the diagnosis of PKU disease, has different methods, including the amount of plasma determining Guthrie test, microbial inhibition, fluorimetric, chromatography and mass spectrometry [ 13 , 14 , 15 , 16 ].…”