Preparation of CeO2 Loaded Chitosan-Based Nanofibrous Membranes for Antibacterial Applications

Ma, Tengfei; Wu, Jianzhuo; Zhai, Xinyun; Du, Yaping

doi:10.21127/yaoyigc20190016

2020

DOI: 10.21127/yaoyigc20190016

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Preparation of CeO2 Loaded Chitosan-Based Nanofibrous Membranes for Antibacterial Applications

Tengfei Ma¹,

Jianzhuo Wu²,

Xinyun Zhai³

et al.

Abstract: CeO2 nanospheres with different diameters were successfully prepared and embedded in one-dimensional chitosan/polyvinyl alcohol (CS/PVA) composite nanofibers by electrospinning technique for further antibacterial evaluation. The obtained composites exhibited different antibacterial activities to Gram-positive bacteria (Staphylococcus aureus) and Gram-negative bacteria (Escherichia coli). We propose that CeO2-CS/PVA nanofibrous membranes with attractive antibacterial activities witness the practical use for tis… Show more

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Recent Advances on Cerium Oxide‐Based Biomaterials: Toward the Next Generation of Intelligent Theranostics Platforms

Huang

Zhang

Jin

et al. 2023

Adv Healthcare Materials

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Disease or organ damage due to unhealthy living habits, or accidents, is inevitable. Discovering an efficient strategy to address these problems is urgently needed in the clinic. In recent years, the biological applications of nanotechnology have received extensive attention. Among them, as a widely used rare earth oxide, cerium oxide (CeO2) has shown good application prospects in biomedical fields due to its attractive physical and chemical properties. Here, the enzyme‐like mechanism of CeO2 is elucidated, and the latest research progress in the biomedical field is reviewed. At the nanoscale, Ce ions in CeO2 can be reversibly converted between +3 and +4. The conversion process is accompanied by the generation and elimination of oxygen vacancies, which give CeO2 the performance of dual redox properties. This property facilitates nano‐CeO2 to catalyze the scavenging of excess free radicals in organisms, hence providing a possibility for the treatment of oxidative stress diseases such as diabetic foot, arthritis, degenerative neurological diseases, and cancer. In addition, relying on its excellent catalytic properties, customizable life‐signaling factor detectors based on electrochemical techniques are developed. At the end of this review, an outlook on the opportunities and challenges of CeO2 in various fields is provided.

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Recent Advances on Cerium Oxide‐Based Biomaterials: Toward the Next Generation of Intelligent Theranostics Platforms

Huang

Zhang

Jin

et al. 2023

Adv Healthcare Materials

Self Cite

View full text Add to dashboard Cite

show abstract

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Preparation of CeO2 Loaded Chitosan-Based Nanofibrous Membranes for Antibacterial Applications

Cited by 1 publication

References 22 publications

Recent Advances on Cerium Oxide‐Based Biomaterials: Toward the Next Generation of Intelligent Theranostics Platforms

Recent Advances on Cerium Oxide‐Based Biomaterials: Toward the Next Generation of Intelligent Theranostics Platforms

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